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What causes elevated PSA during testosterone therapy?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

My prostate-specific antigen (PSA) value has got increased by 30 % from 0.8 ng/mL to 1.1 ng/mL. I am in testosterone replacement therapy also. Please advice.

Hi,

Welcome to icliniq.com.

The absolute PSA (prostate-specific antigen) level is in the range where it is not of much concern. But the rise in PSA is bothersome if it rises more than 0.75 ng/mL per year. For a young patient like you, even this rise in rate needs to be assessed. Testosterone replacement can also be a cause of this rise. Please mention about the reason for taking testosterone replacement therapy.

Patient's Query

Thank you doctor,

I was diagnosed with low testosterone before five years, and I am taking testosterone injection 3.3 fl oz per week.

Hi,

Welcome back to icliniq.com.

I have gone through the attachment (attachment removed to protect patient identity). You have to repeat PSA after three months. Also, it is not necessary to take continuous testosterone replacement for a low borderline level. At present, it is not of much concern. Repeat it after three months. You can do pranayama or yoga along with other exercises to improve the general wellbeing.

Medically reviewed byiCliniq medical review team

Published At September 28, 2017
Reviewed AtMay 29, 2024

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