Q. Please suggest medicine for my laughing problem.

Answered by
Dr. Aida Abaz Quka
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Mar 29, 2017 and last reviewed on: Aug 05, 2021

Hello doctor,

I have a problem with laughing. I laugh without any reason, and I cannot control the laugh. I laugh while speaking to others or on the phone without reason. It is a problem to me and my career. I cannot do a job with this laughing problem. I have seen on the internet that laughing without any reason is PBA. Please suggest me medicine to cure the problem.



Welcome to

  • I carefully read your question and would explain that your symptoms seem to be related to pseudobulbar affect. For this reason, I would first recommend performing a brain MRI to investigate the possible causes underlying your symptoms.
  • An electromyography is also necessary to exclude possible ALS (amyotrophic lateral sclerosis).
  • Regarding medication, I suggest trying Nuedexta (Dextromethorphan and Quinidine). It is the only specific drug for this condition. But, it should be given under medical prescription.
  • Other drugs to consider would be antidepressants like Sertraline or Paroxetine.

The Probable causes:

Stroke, dementia and ALS.

Investigations to be done:

Brain MRI.

Treatment plan:


Regarding follow up:

For further information consult a neurologist online.--->

Hi doctor,

I searched for Nuedexta tablets, but I did not find anywhere. Can you please suggest me any other name with same formula and dosage?



Welcome back to

  • It contains Dextromethorphan and Quinidine. If you do not find it, then I would suggest Sertraline 50 mg daily.
  • You should start with half a tablet for a week and then increase the dose to 50 mg daily. Consult your specialist doctor, discuss with him or her and take medicine with consent.

The Probable causes:

Dementia and ALS.

Investigations to be done:

Brain MRI.

Differential diagnosis:


Regarding follow up:

For further information consult a neurologist online.--->

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
What is the chance of getting ALS if someone in the family had it?

fasciculations (muscle twitches) in the arm, leg, shoulder, or tongue ...   Read full

My left ear is blocked when I get cough and sore throat. What should I do?

We usually prescribe tablet Azee (Azithromycin) 500 mg once a day for three days along with tablet Pantoprazole 40 mg before breakfast for three days ...   Read full

In ALS, are symptoms present on both sides of the body?

.. your query and understand your concerns. I can state with 100 % confidence that no ALS (amyotrophic lateral sclerosis) presents over the 18 years. It is a progressive illness and once started, there is gradual deterioration. As symptoms experience...   Read full


Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

JAK Inhibitors in Treating Rheumatoid Arthritis
Doctors mainly suggest JAK or Janus kinase inhibitors for patients with rheumatoid arthritis to ease their symptoms. Rea...  Read more»
Importance of Sex Hormones - Types, Functions, Normal Ranges, and Roles
Sex hormones are steroids produced in the body that control sexual development, pregnancy, and overall health. Read belo...  Read more»
Fallopian Tubes - Anatomy, Function, and Diseases Affecting It
Fallopian tubes are important structures of the female reproductive tract. This article discusses the same below.  Read more»

Ask your health query to a doctor online?

Ask a Neurologist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.