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Why is my neutrophil number dropping?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I recently had my blood tests done for unexplained bruising, mouth sores, muscle pain, and headaches. The neutrophil number came back as low as 1.2. I looked back at my past laboratory results and the neutrophil number has been dropping as follows. First, it was 3.4, then 3.2, 2.9, 2.7, 2.1, and now 1.2. Could this be a sign of something more serious? I take Enbrel for psoriatic arthritis and also, my immune system is low.

Answered by Dr. Prakash. H. M.

Education:

MBBS

Professional Bio:

Dr. Prakash H. M. is an experienced Pathologist with expertise in clinical pathology, hematology, histopathology, and cytology. He plays a crucial role in accurate disease diagnosis through laboratory testing and microscopic analysis. With a strong foundation in medical diagnostics, Dr. Prakash ensures reliable and timely reports that support effective treatment decisions. His precision and commitment to quality make him a trusted expert in the field of pathology.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

Based on your query, my opinion is as follows:

  1. If the immune system were being affected, then I would like to look at the whole picture of WBC count (white blood cell) and decide.
  2. Psoriatic arthritis is a chronic disease and in chronic diseases, the lymphocytes increase. When the counts are being done, the count is usually done for 100 cells.
  3. If lymphocytes increase, the neutrophils will reduce and if the neutrophils increase, the lymphocytes will reduce. As you have psoriatic arthritis, other WBC would have increased and hence neutrophils is appearing low.
  4. Unexplained bruising is probably related to platelet count. If the platelet count is normal, then it could be a complication of psoriatic arthritis on blood vessels.
  5. The muscle pain and headaches could be due to psoriatic arthritis. The mouth sores could be due to side effects of Etanercept.
  6. If the immune system were to be affected, both lymphocytes and neutrophils would be reduced or the whole WBC count and if there was bone marrow suppression, all cells including RBC and platelets would be affected.
  7. At present, as the lymphocytes are increased, the neutrophils appear to be reduced. The symptoms are more of a side effect of psoriatic arthritis and its treatment. Nothing serious related to neutrophils. Not to be worried.
Medically reviewed by Dr. Hemalatha
Published At July 10, 2016
Reviewed At February 7, 2024

Education:

MBBS

Professional Bio:

Dr. Prakash H. M. is an experienced Pathologist with expertise in clinical pathology, hematology, histopathology, and cytology. He plays a crucial role in accurate disease diagnosis through laboratory testing and microscopic analysis. With a strong foundation in medical diagnostics, Dr. Prakash ensures reliable and timely reports that support effective treatment decisions. His precision and commitment to quality make him a trusted expert in the field of pathology.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. Hemalatha is a dedicated Dental Surgeon with expertise in preventive, restorative, and cosmetic dental care. She is passionate about promoting oral health and creating personalized treatment plans to suit each patient’s needs. Her clinical approach emphasizes patient comfort, precision, and long-term dental wellness, ensuring a positive and reassuring experience for every individual under her care.

This doctor is not available for online consultations on the platform anymore.

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Education:

MBBS

Professional Bio:

Dr. Prakash H. M. is an experienced Pathologist with expertise in clinical pathology, hematology, histopathology, and cytology. He plays a crucial role in accurate disease diagnosis through laboratory testing and microscopic analysis. With a strong foundation in medical diagnostics, Dr. Prakash ensures reliable and timely reports that support effective treatment decisions. His precision and commitment to quality make him a trusted expert in the field of pathology.

This doctor is not available for online consultations on the platform anymore.

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