Q. I am on Tramadol and Priligy for premature ejaculation. Is there risk of serotonin syndrome?

Answered by
Dr. Anshul Varshney
and medically reviewed by iCliniq medical review team.
Published on Nov 16, 2019

Hello doctor,

I am taking 100 mg Tramadol and 60 mg Priligy (Dapoxetin) for the treatment of premature ejaculation before having sexual intercourse. The result is my intercourse time has increased from two minutes up to 45 minutes without having ejaculation. With Priligy or Tramadol alone it is around a maximum of five minutes. My question is, can this dosage combined cause serotonin syndrome or is the dosage still at a moderate level? Would it help to reduce the risk if I reduce Tramadol to 5mg and Priligy to 30mg?

Dr. Anshul Varshney

Critical Care Physician Diabetology General Medicine Internal Medicine Medical Gastroenterology Nephrology Pulmonology (Asthma Doctors) Rheumatology
#

Hello,

Welcome to icliniq.com.

Serotonin syndrome will not occur when you consume high doses of SSRI (selective serotonin reuptake inhibitors) and then stop abruptly. My advice to you would be a safer way out. You should continue with Dapoxetine 60 mg and avoid Tramadol. If you do not get adequate time, then add up anesthetic jelly. You need to apply it on your penis 20 minutes prior to intercourse and wear a condom. You would get a wonderful time I am sure of that.

I hope this helps.

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