Can I have lymphoma, kidney diseases, and eye problems due to secondary Sjogren's syndrome?

Q. Is it true that primary Sjogren's syndrome is less severe than Secondary Sjogren's syndrome?

Answered by
Dr. Mohamad Ali Rida
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Jun 12, 2022 and last reviewed on: Aug 17, 2023

Hello doctor,

I have had dermatomyositis for three years and was asked to take tablet Cellcept. Before being diagnosed with dermatomyositis, I developed dry eye disease due to meibomian gland dysfunction. After taking the medicines, I had dryness in my mouth. I tested negative for anti-SSA Ro and anti-La/SSB antibodies for Sjögren's syndrome a few years ago. Recently I developed Demodex rosacea. My rheumatologist suggested I might have secondary Sjögren's syndrome. Is secondary Sjögren's syndrome serious? I read that Sjögren's syndrome can cause dryness of the eyes and ears, kidney problems, and lymphoma. Can secondary Sjögren's syndrome cause lymphoma and other serious issues? Is primary Sjogren's syndrome the same as secondary Sjogren's syndrome?

Thank you.



Welcome to

Do not worry, as you are receiving the best treatment for dermatomyositis. Secondary Sjogren's syndrome is a very common autoimmune disease. Being on tablet Cellcept (Mycophenolate mofetil 500 mg) is more than enough to prevent complications of Sjogren's syndrome. You must follow-up regularly with your doctor for any swollen lymph nodes.

Thank you doctor for the reply,

Is it better to have secondary Sjögren’s syndrome than primary? Is there less risk of organ damage or lymphoma in primary Sjogren's syndrome?



Welcome back to

Primary Sjogren's syndrome is less severe than secondary. However, there are no studies available to compare both. Therefore, I am answering your query based on my clinical observation. The risk of lymphoma is present in all rheumatic diseases, including dermatomyositis. Therefore I do not think you should be worried about Sjogren's syndrome. You just need a regular check-up and careful examination.

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
What is the ayurveda treatment for eye pain?

This is called dry eye syndrome ...   Read full

The biopsy of my skin rash showed interface dermatitis with mucin. Do I have lupus?

Is a biopsy conclusive for these diseases ... The rashes that you are describing along with the biopsy findings can go in favor of a connective tissue disease ...   Read full

Is there any difference between Sjogren's syndrome and SLE?

Because of these, the patient has a gritty feeling in the eyes most of the day and difficulty in chewing and deglutition of food ...   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

PCOS and Liver Problems
The hormonal imbalances in polycystic ovary syndrome could cause liver diseases. Read the article to know the relationship between these medical conditions.  Read more»
Inferior Alveolar Nerve Lateralization Technique
The inferior alveolar nerve lateralization technique is a surgical lateralization technique to reposition the nerve. Read the article to know more about this.  Read more»
COVID-19 and Ebola: Similarities and Differences
This article gives a comparison and broader overview of the outbreak of the two deadliest diseases that showed a greater incidence over the last two decades.  Read more»

Ask your health query to a doctor online?

Ask a Rheumatologist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.