Why do rashes occur on the body after hip replacement?

Question

Hello doctor,

I had a total hip replacement a few days back. Yesterday, I started developing a rash on my torso, back, buttocks, and legs. The palms of my hands and soles of my feet are red and painful. I had an epidural and sedation for my hip surgery. I had two rounds of intravenous (IV) antibiotics after surgery. I do not know what kind.

For pain, I have been given Oxycodone, Tylenol, and Toradol for inflammation. I have also been given Colace, Pepcid, Ranitidine, Aspirin, and Celebrex. The doctors here at the hospital are stumped as to what is going on with this rash. It is not terribly itchy, mainly when I get a bit overheated. I have had this happen to me before, 15 years ago, after undergoing a D and C (dilation and curettage). It did resolve in about four weeks, but the skin on my palms and soles blistered and peeled before it all went away. If you have any idea what this could be and what I could do to lessen the effects, I would greatly appreciate it.

Kindly help.

Answer 1

Hello,

Welcome to icliniq.com.

I read your query and can understand your concern.

I have seen the attached photograph (the attachment was removed to protect the patient's identity). As per the details, it seems that you are having a condition called drug rash. Drug rash may manifest as redness of the skin, blisters, red raised rash, peeling of the skin, urticaria, etc.

Mostly the rash is itchy but the presentation may vary. As per history, you got the rash post-surgery or any intervention both times although the presentation was different. So, in my opinion, you have developed a rash in response to some medication. It may be due to antibiotics or painkillers you must have received both times.

The best treatment for this is the prevention of further rash or aggravation by avoiding the offending drug. Antihistamines and topical emollients give symptomatic relief and decrease allergic reactions.

Kindly consult a specialist doctor, discuss with them, and take medications with their consent.

I hope this helps.

Thank you.