HomeAnswersMedical Gastroenterologyulcerative colitisMy daughter has ulcerative colitis. Is it normal to get white mucus in her stools?

Can the treatment for ulcerative colitis cause white mucus in the stools?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At April 28, 2022
Reviewed AtAugust 30, 2023

Patient's Query

Hello doctor,

My daughter is your old patient. Just to recall, she had ulcerative colitis. She was taking tablet 6-MP 25 mg every other day along with folic acid. After the colonoscopy, you suggested 25 mg tablet 6-MP each day with 2 gm Pentasa and 5 mg folic Acid. We did a couple of blood tests after a few months. The other doctor felt her liver markers were elevated and reduced the dose of the 6-MP tablet. We were not sure how to contact you, So we followed her. After that, we did one more blood test. There was no increase in WBC or RBC. But now, nearly after a month and a half, she is taking 25 mg every other day, and we are seeing white mucus in her stools on and off. She has no belly pain or other symptoms. Frequency is mostly one time a day, and for the last couple of days, it has been twice a day with formed stool. We will be doing one more blood test tomorrow. I am uploading the first two blood test reports now. I will send the next one when it is available. Her current medication is tablet 6-MP 25 mg every other day, Rowasa 2 gm per day, and folic acid 5 mg per day. In the last six months, we have done three calprotectin stool tests. The values were 363, 70 (after four months), and 33 (after two months), respectively. Please advice. Thank you.

Hello,

Welcome to icliniq.com.

I read your query and understand your concern.

After reviewing the history, it looks like an overdose of 6-MP (Mercaptopurine). I suggest you continue the 6-MP tablet on alternate days. LFT (liver function tests) report was normal. Occasional mucus in stool can be ignored.

I suggest you to repeat the calprotectin stool test and LFT. Please send me the reports and watch for blood in her stools.

HB (hemoglobin) is normal.

Need not worry, as she is in remission. I suggest you to continue Pentasa (Mesalazine) 2 gm daily and folic acid.

I also suggest you to kindly give her a vitamin B12 injection and take advice from your gastroenterologist.

Thank you.

Patient's Query

Thanks a lot, doctor,

I am attaching her latest blood reports. We will soon take a calprotectin stool test and will forward the reports for the same.

Thanks.

Hi,

Welcome back to icliniq.com.

I understand your concern.

Reports were noted (attachments removed to protect the patient's identity). I can see that-

1. CRP (C-reactive protein test) is normal.

2. Vitamin levels are low, so I suggest you give her some supplementation.

3. High 6-MP metabolites are present, so I suggest you continue the lower dose.

I will review with fecal calprotectin report.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Murugesh Mallaiyappan
Dr. Murugesh Mallaiyappan

Medical Gastroenterology

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