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Digital Pathology - The Great Solution From Past to Future

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Digital pathology revolutionizes the analysis of tissues and enhances efficiency, accuracy, and collaboration in the medical world. Read to know more.

Written by

Dr. Suhaila

Medically reviewed by

Dr. Mona Kamal Farid Zaki

Published At April 26, 2024
Reviewed AtApril 26, 2024

Introduction

Pathology is the study concerned with the examination of the samples of tissues, generally using glass slides and microscopes. It can also be explained as a field of medicine that has its abscess in interpreting cell biology with the help of images. Digital pathology has gained significance in recent years due to the emergence of digitalization in imaging. This demarks a milestone in revolutionizing the field of medical diagnosis and treatment. It has transformed the way the samples are analyzed and interpreted. Its technological advancement has also opened new doors for good quality research and education. This article explores the world of digital pathology, its applications, and future considerations to make diagnostics more advanced and perfectly accurate.

How Is Digital Pathology Different From Traditional Pathology?

  • Sample Processing: In traditional methods, glass slides are used and generally have to be delivered to the laboratory after procurement for processing. The glass slides have the tissue prepared, staining with dyes is done, and the slides are analyzed using a microscope. Meanwhile, in the digital system, tissue samples are scanned, which results in the creation of images. Special digital scanners are used to procure images. These images can further be analyzed and modified using software.

  • Image Analysis: Most digital systems come with specialized tools for analyzing and annotating images. This helps automate tasks and makes the entire diagnostic process efficient. The systems also have the option of creative viewing and checking multiple section levels. Stain views can also be viewed simultaneously, giving a clearer view and better analysis.

  • Storage of Data: The digital slides can be archived and easily retrieved when required. In comparison with traditional methods, there is a need for storage space for the glass slides. And timely access is a huge disadvantage there.

  • Accessibility: The laboratory has the advantage of faster access for a first-in, first-out workflow. The digitized slides are sorted in a computer, thus being more efficient and reducing the turnaround time. Another advantage is that pathologists from anywhere can access the images with an internet connection, considerably decreasing the commute or delivery time.

  • Ease of Consultation: These digital pathological services utilize more immediate remote consultations. This makes it easier for physicians to collaborate and consult other doctors when needed, leading to less waiting time, early diagnosis, and prompt treatment initiation. Another advantage is the ease of getting second opinions from experts in the field.

What Are the Applications of Digital Pathology?

  • Diagnosis: It helps physicians diagnose conditions and disorders faster and more accurately. The high-resolution images of the cells, tissues, and organs help greatly. The earlier the diagnosis is made, the more promptly the intervention starts, considerably improving the patient's quality of life.

  • Educational Training: Digital pathology platforms help students and upcoming doctors study and learn in detail about the anatomy and physiology of various tissues and organs. This helps raise the next generation of well-trained pathologists who can overcome the health disparity.

  • Research: The images used in digital pathology can also provide the researchers with real-time data on the disease pathogenesis. Also, various therapeutic agents can be studied on the cells and further researched to study the effect of the medicine on the diseases.

  • Telepathology: Using digital pathology, the images can be transmitted electronically to get second opinions and for expert consultation. Since the images are digitized, it is very convenient to send them.

What Are the Limitations of Digital Pathology?

  • Standardization: There needs to be more standard practice in this field. Multiple software programs exist, each with a different operating system. This can sometimes lead to problems when sharing images and results between laboratories and hospitals.

  • Heavy Costs: The setup and software needed are costly compared to traditional methods. Therefore, not all laboratories and hospitals have the required armamentarium and software. Another costly factor would be the training fees for all the pathologists, as most are trained only to use the microscope in the curriculum.

  • Legal Issues: Certain issues, such as data privacy, security, and liability, may create further hurdles for the widespread adoption of digital pathology systems. Clear guidelines will help in this regard.

  • Technical Faults: Digital pathology might sometimes introduce artifacts due to image display, compression, or capturing related artifacts. When these occur, they can affect the image's quality, requiring optimization.

  • Learning Curve: Pathologists who have been using traditional methods for a long might take time to learn the systems and software initially. They need to become more familiar with the systems and find it easier and faster to use traditional methods. Also, there have been reports where experienced pathologists are used to a microscope and can quickly access any location of the slide using traditional methods. Hence, they prefer the traditional hands-on approach.

What Are the Future Considerations for Better Utilizing Digital Pathology?

  • Artificial Intelligence: Incorporating artificial intelligence algorithms into digital systems helps decrease many errors and accurately assist the pathologist in identifying and characterizing the pathological entity.

  • Cloud-Based Technological Solutions: They are data repositories that store, organize, and retrieve data when needed. Using these, images can be stored along with the patient's electronic health records, which benefits both the patient and the practitioner.

  • Virtual Reality: This involves introducing a telerobotic system with a virtual microscope concept. The goal is to support the clinician remotely in real-time through high-quality imaging and detailed analysis.

  • Precision Medicine: Digital pathology can add a layer of extra detailed information when viewing an image in a spatial context. This helps a great deal in personalized medicine and provides the individual with the best possible treatment.

Conclusion

To conclude, the world of digital pathology is a field in diagnostics with immense benefits and potential. It can revolutionize medicine with faster diagnosis and early treatment and greatly improve the quality of a patient’s life. By integrating artificial intelligence algorithms and virtual reality, it is possible to improve patient outcomes and advance medical practice. The limitations, such as learning time and standardization, can be overcome by educating people and implementing policies that promote standard practice.

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Dr. Mona Kamal Farid Zaki
Dr. Mona Kamal Farid Zaki

Pathology

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