HomeHealth articleshair lossWhat Is the Relation of Chemotherapy and Hair Loss?

Chemotherapy and Hair Loss

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Cancer treatments often cause temporary hair loss. For many cancer patients, chemotherapy stops progression, and potential adverse effects include hair loss.

Medically reviewed by

Dr. Rajesh Gulati

Published At April 29, 2024
Reviewed AtApril 29, 2024

Introduction

Specific chemotherapy regimens can cause alopecia, leading to the complete or partial loss of hair on the scalp and other parts of the body. Radiation therapy can cause hair loss in the specific location of the body being treated. Alopecia is the precise medical terminology used to describe the condition of losing hair. Seek advice from medical experts to ascertain whether the cancer treatment that one may undergo is linked to hair loss.

What Is the Underlying Reason for Hair Loss During Chemotherapy?

Chemotherapy employs potent medications that target rapidly proliferating cancer cells and harm other rapidly proliferating cells in the body, including the cells located in the roots of the hair. Chemotherapy can induce alopecia, affecting hair growth on the entire body rather than just the scalp. Occasionally, one may experience the shedding of eyelashes, eyebrows, armpit hair, pubic hair, and other bodily hair. Certain chemotherapy medications have a higher likelihood of causing hair loss compared to others. Varying dosages can lead to various effects, including mild hair thinning or total hair loss.

What Is the Duration of Hair Loss Caused by Chemotherapy?

Typically, hair loss commences within two to four weeks following the initiation of treatment. The hair may rapidly shed in large clusters or gradually over time. Hair loss commonly persists during treatment and for a few weeks thereafter. The outcome of the treatment will determine whether the hair experiences thinning or full baldness. Engage in a conversation with the healthcare team regarding the specific chemotherapy medications to be administered to patients.

What Is the Timeline for Hair Regrowth Following Chemotherapy?

The hair recovery and regrowth process may take several weeks after treatment. Hair regrowth often occurs within three to six months following the completion of the treatment. As the hair regrows, it is likely to exhibit subtle variations compared to the hair that is gone. However, the distinction is typically transitory.

The texture or color of new hair may vary. The current state of the hair may exhibit a higher degree of curliness than its previous state. Alternatively, the color of the hair may remain gray until the cells responsible for regulating its pigment regain functionality.

Is It Possible to Avoid Hair Loss Caused by Chemotherapy?

There is currently no medication available that guarantees that hair will not fall out during or after chemotherapy. Various treatments have been examined as potential methods to mitigate hair loss. Nevertheless, they have yet to be entirely productive.

Do Cold Caps Have the Potential to Mitigate Hair Loss Caused by Chemotherapy?

Research on scalp cooling caps and other methods of scalp hypothermia has demonstrated moderate effectiveness in most individuals who have utilized them.

  • Scalp hypothermia is a therapeutic procedure that involves deliberately cooling the scalp. Throughout chemotherapy treatments, a snugly fitting cap cooled by chilled liquid can be positioned on the head. The cool temperature reduces the rate of blood circulation to the scalp. By employing this method, the likelihood of chemotherapy medications impacting the hair is reduced.

  • The utilization of scalp hypothermia carries a minimal but potential risk of scalp cancer. This discrepancy occurs because this specific region does not receive an equivalent amount of chemotherapy compared to the remainder of the body. Individuals undergoing scalp hypothermia experience sensations of extreme coldness and frequently report experiencing headaches.

  • Several studies have indicated that cooling caps may not be effective on hair with tightly curled or coiled patterns. This hair type is predominantly found in individuals of African descent. Tight curls and coils may impede the cap's ability to cool the scalp sufficiently. An altered hairstyle may be necessary to ensure a snug fit of the hat on the head.

Is It Possible for Drugs to Stimulate Hair Regrowth Following Chemotherapy?

Minoxidil, often known as Rogaine, is a pharmaceutical agent employed to treat alopecia, a condition characterized by hair loss. Administering Minoxidil topically to the scalp before and during chemotherapy is unlikely to have a preventive effect on hair loss. Nevertheless, certain studies indicate that it can accelerate the process of hair regeneration. Further investigation is required to ascertain the efficacy of Minoxidil in promoting hair regrowth following cancer treatment.

How to Manage Hair Loss Caused by Chemotherapy?

Experiencing distress over hair loss is a common and expected reaction among individuals. Hair loss can serve as a visible indication to others that patients are experiencing cancer and are currently receiving medical treatment. Engaging in a conversation with the medical staff regarding the concerns and proactively adopting measures to anticipate the potential occurrence of hair loss might be beneficial. There are strategies to mitigate the emotional discomfort caused by hair loss during chemotherapy treatment.

  • Certain individuals opt to trim their hair to a very low length or completely remove it by shaving their head in anticipation of hair loss. It is advisable to use an electric razor while opting to shave to prevent cuts. Additionally, one may use head coverings such as scarves, hats, or wigs. Certain individuals interchangeably don wigs and other head coverings, such as scarves. They may also choose to purchase additional wigs. Moreover, certain individuals opt not to conceal their heads after they experience hair loss.

  • If a person is considering using a wig, it is advisable to purchase it before or during the beginning stages of treatment.

  • Wigs can be made from either human hair or synthetic materials. Each category incurs distinct expenses and necessitates specific upkeep. To ensure a more accurate match between the wig color and the natural hair color, it is advisable to utilize natural light sources such as outdoor sunlight or light coming through a window. Ensure the wig has an adjustable feature, as the head size may decrease during hair loss.

Conclusion

Chemotherapy often leads to alopecia, a prevalent adverse effect. However, strategies exist to handle this condition effectively. Consult the oncology team regarding the likelihood of experiencing alopecia as a consequence of medical intervention. Patients may opt for a brief haircut, explore the use of scalp cooling caps, or initiate the selection of a wig.

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Dr. Rajesh Gulati
Dr. Rajesh Gulati

Family Physician

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