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Night Sweats and Cancer: Is It a Sign

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Night sweats can be a sign of lymphoma, tuberculosis, and infection. Read this article to know more.

Medically reviewed by

Dr. Rajesh Gulati

Published At February 14, 2024
Reviewed AtMarch 5, 2024

Introduction:

Night sweats are a common phenomenon that affects many individuals at some point in their lives. It is characterized by excessive sweating that occurs at night, typically while sleeping. Night sweats can result from many factors, including menopause, anxiety, and certain medical conditions. One medical condition that is associated with night sweats is cancer. Cancer is a disease that affects the cells in the body and can cause various symptoms, including night sweats. Night sweats can be an early sign of cancer in some cases, indicating that the body is fighting off the disease. However, it is important to note that not all night sweats indicate cancer. Many other medical conditions can cause night sweats, such as infections, autoimmune disorders, and hormonal imbalances. It is important to consult with a healthcare provider if experiencing night sweats, especially if they are persistent and accompanied by other symptoms.

What Are Night Sweats?

Night sweats are defined as excessive sweating during the night. The absence of excessive daytime sweating characterizes night sweats. Night sweats are characterized by overnight sweating that occurs just while asleep. The location of sweating is on the palm or face. Most definitions do not include environmental elements like humidity or room temperature. Therefore, night sweats are not necessarily symptoms always.

Night sweats can be mild, moderate, and severe.

The following are the types of night sweats:

  • Mild: No bathing or change of clothing is required.

  • Moderate: Sleep disturbed by the need to arise and wash face or other affected body areas, but no clothing change.

  • Severe: Both or clothing change is required.

What Are the Causes of Night Sweats?

The exact cause of night sweats is unknown. However, night sweats can be a symptom of some diseases.

The following are the diseases in which night sweats are noticed:

  • Cancer - Some cancers can cause sweating more than usual. Night sweats can be an early sign of cancer. Night sweats are observed in a few malignancies, such as:

  1. Lymphoma (cancer of the lymphatic system).

  2. Leukemia (blood cancer).

  3. Osteosarcoma (bone cancer).

  4. Lung cancer.

  5. Liver cancer.

  6. Non-Hodgkin lymphoma.

  7. Hodgkin lymphoma.

  • Infections - Some infections can also cause night sweats.

  1. Tuberculosis (infection of the lung).

  2. Human immunodeficiency virus infection.

  3. Fungal infection (histoplasmosis, coccidioidomycosis).

  4. Lung infection.

  5. Endocarditis (inflammation of the layer of the heart).

  6. Bacterial infection.

  • Drugs - Some medications can cause night sweats. Night sweats are absorbed in people with alcohol and drug abuse.

  1. Antipyretics.

  2. Antihistamines.

  3. Phenothiazines.

  4. Alcohol abuse.

  5. Heroin abuse.

  6. Antidepressant.

  7. Steroids.

  • Other - Some conditions can also cause night sweats. These are:

  1. Menopause (a condition in which the menstrual cycle stops around the age of 45 years in the woman).

  2. Diabetes mellitus (low blood sugar).

  3. Stress.

  4. Anxiety.

What Are the Advantages Of Sweating?

Sweating is complicated to regulate because it involves both thermoregulatory and non-thermoregulatory mechanisms.

The following are the advantages of sweating:

  • When the core body temperature exceeds thresholds, sweating helps to lower it. Therefore, sweating helps to regulate body temperature.

  • Sweating helps flush out toxins and impurities from the body through the skin's pores.

  • Sweating helps unclog pores and keep the skin moisturized, preventing acne and other skin problems.

  • The sweat glands produce immunoglobulin A, an antibody that helps to boost the immune system.

  • Sweating can help to relieve stress by releasing endorphins, the body's natural feel-good chemicals.

  • During physical activity, sweating helps regulate body temperature and maintain fluid balance, improving athletic performance.

  • Sweating decreases during rapid eye movement sleep.

Are Night Sweats a Sign of Cancer?

Night sweats can be a sign of cancer. In addition, night sweats can be a symptom of various conditions such as tuberculosis, lymphoma, lung abscess, bacterial endocarditis, diabetic autonomic neuropathy, nocturnal hypoglycemia, nocturnal angina, and diabetes insipidus. Cancer-related night sweats can occur due to the body's natural response to the disease. For example, when cancer cells grow and multiply, the body may respond by producing more heat, which can cause excessive sweating at night. Additionally, certain types of cancer, such as Hodgkin's lymphoma, can affect the body's nervous system and cause night sweats. If cancer is suspected as the cause of night sweats, a healthcare provider may order various tests to diagnose the condition. These tests may include blood tests, imaging studies, and biopsies. If the test results indicate that the night sweats are related to cancer, a healthcare provider will develop a treatment plan tailored to the specific type of cancer and its stage.

How Night Sweats Treated?

It is important to note that excessive sweating, or hyperhidrosis, can be a sign of an underlying health condition and should be evaluated by a healthcare provider. Night sweats can be an early sign of cancer. The healthcare provider can diagnose the underlying cause and recommend the appropriate treatment.

The following are the treatments for night sweats:

  • Hormonal Therapy - Hormonal therapy, such as estrogen replacement therapy, is recommended for women experiencing night sweats due to menopause.

  • Antidepressants - Certain types of antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), can help to reduce hot flashes and night sweats in some individuals. Antidepressants are suggestive in patients suffering from depression. Alpha-adrenergic blockers may be effective in patients taking serotonin reuptake inhibitors.

  • Antibiotics - If an infection is the cause of the night sweats, antibiotics may be prescribed to treat the infection.

  • Lifestyles Changes - Making lifestyle changes, such as keeping the bedroom cool, avoiding spicy foods and caffeine, and practicing relaxation techniques, can help reduce night sweats' frequency and severity.

  • Anti-cancer Drugs- Nabilone, thalidomide, and thioridazine may be effective for patients with terminal cancer.

Conclusion:

Night sweats can be a sign of cancer, but it is important to understand that not all night sweats are caused by cancer. If someone is experiencing persistent night sweats, it is essential to consult a healthcare provider to determine the underlying cause and develop an appropriate treatment plan. Early detection and treatment are key to ensuring the best outcome for cancer patients. Little lifestyle changes can resolve night sweats. Avoiding spicy foods, caffeine, stress, and keeping the bedroom cool can reduce the frequency and severity of the night sweats.

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Dr. Rajesh Gulati
Dr. Rajesh Gulati

Family Physician

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