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Injectable Cellulite - An Overview

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This article is about injectable cellulite, its working, and the risks associated with cellulite injections. Read this article to know more.

Written by

Dr. Swathi. R

Medically reviewed by

Dr. V. Srikanth Reddy

Published At October 18, 2023
Reviewed AtJanuary 30, 2024

Introduction

After many years the FDA (Food and Drug Administration) approved a new cellulite treatment that can promise quick results. QWO (collagenase clostridium histolyticum cellulite) is a new treatment that recently received approval from the FDA to treat the cellulite in the buttocks region of women. Cellulite injections allow cosmetic surgeons to achieve a smooth dimple-less skin surface on the buttocks through an injectable technique. Cellulite shots are as effective as the clinical trials that suggest treating cellulite can be a more straightforward procedure than ever. Cosmetic surgeons do these procedures of cellulite injections.

What Are Cellulite Injections?

Cellulite develops when the fat collection pushes against the skin’s connective tissue. As a result, the skin in the area appears puckered or dimpled. Cellulite is graded from zero to three based on the intensity of the developed dimpled appearance. Cellulite is a concern for almost every female after the puberty period. Dimple skin appearance most commonly occurs on the buttocks, abdomen, and thighs. In addition, sometimes, it appears on the breasts and the upper arms. It is believed that cellulite is not connected with obesity. Instead, cellulite is caused by the hormones in the body. Individuals have become more comfortable using botox injections and other injectable treatments for treating skin conditions. So, it was concluded that such injectable treatment would successfully cure skin issues like cellulite. The mechanism of action of QWO treatment is similar to other presently available treatment modalities like lasers, and it is also less invasive.

What Is the Physiology Of Cellulite?

Inside the skin's dermis, fibrous bands of collagen are seen, called fibrous septate, connecting the skin to the underlying muscles. This separates lobes that partition fat in the sub-dermis, called the third layer of skin. Cellulite is formed when the bands of septae fibers shrink and thicken. This deformity causes it to tug down the fibers where it is already attached to the skin. The tension generated in the lobes leads to a dimple appearance associated with the cellulite. Cellulite injections are entirely harmless, and their effects on the skin cause concern for some women since a new treatment is available for reducing cellulite without using any scalpels or intense lasers.

How Does the Injection Work?

Before discussing the mechanism of QWO, one must know a few basics about cellulite.

  • Cellulitis is the dimpling of the skin around the pockets of fat. Cellulite is not a type of skin sagging or skin laxity.

  • Cellulite is caused mainly by bands of collagen, or the septate, seen as a rope of chain in the skin to the muscles. Fat is deposited between the muscles and the skin. These dimples are caused by the septae that tighten the skin to the muscle. As a result, the fat becomes encircled in dimples or divots.

  • There is no permanent treatment available for cellulite. Many variable cellulite treatments are available, including lasers, energy treatments, and tiny incisions. The longest of any of these lasts for three years. The treatments that remove the fat, such as liposuction, do not treat cellulite.

  • About 85 to 90 percent experience cellulite regardless of weight -Most men do not experience cellulite as often because of the septae beneath the skin in a different form.

The doctor injects the injection directly into the cellulite dimples on the buttocks. Nearly twelve injections for a single treatment or up to 24 injections for about two treatments are administered. Once the injection is done, the enzyme in the QWO is believed to target collagen types one and three. This further causes releasing of the septae. This helps in removing the dimple ultimately and makes the skin appear smooth. It is one of the types of clinical trials in which the QWO was injected three times, each 21 days apart, to produce the results in the patients.

How Does QWO Work When Compared With Cellulite Treatments?

Other available cellulite treatments also work by separating the septae. There is a tiny blade available to sever the bands. It works with thermal energy rather than the laser. The oldest cellulite treatment uses the mechanical way of cutting the septae using the cannula. The significant difference with the QWO was to loosen the septae chemically. By comparison, QWO was invasive and required less time for treatment.

QWO is FDA-approved for treating cellulite in women. Clinically it helps to reduce the severity of dimpling since the participants will receive three injections each for 21 days apart.

What Are the Benefits of QWO?

The following are the benefits of QWO:

  • It aids in lessening the visibility of cellulite.

  • It helps in smoothing dimpled skin.

  • It is only a ten-minute procedure.

  • It is the one that is scientifically proven.

  • It works immediately and also gives long-lasting results.

What Is the Result Expected While Using QWO?

QWO makes the cellulite treatment quicker and also more accessible than before. The injection takes about as minimal as ten minutes. Each visit may include two treatment areas on the other side of the buttocks. But, the patient is expected to have a realistic expectation. As with other cellulite treatment options, QWO too reduces the condition, but total eradication may not be possible. Smoothening effects from the treatment may last longer than 90 days. However, no exact data shows how long the smoothing results will last.

What Are the Side Effects Seen in Injectable Cellulite?

QWO is one of the least invasive cellulite treatments clinically proven to give the best results. The side effects are usually local to the injection site and include:

  • Pain.

  • Swelling.

  • Redness.

  • Itching.

  • Nodule formation.

  • Discoloration.

However, more studies are needed to confirm the procedure's long-term safety.

Conclusion:

Injectable cellulite treatment shows better results without using any intense lasers or scalpels. Patients are benefited due to their long-time smoothening effect on skin with reduced dimples on the skin. These methods are equally effective compared to other treatment options and less invasive. The smoothening effects are found to last for more than ninety days. However, more studies are needed on the long-term side effects and effectiveness.

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Dr. V. Srikanth Reddy
Dr. V. Srikanth Reddy

Dermatology

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