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Pediatric Schizophrenia - Causes, Symptoms, Diagnosis, and Treatment

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Childhood schizophrenia is a mental illness affecting children younger than 13 years. It is also referred to as early-onset schizophrenia.

Medically reviewed by

Dr. Vishal Anilkumar Gandhi

Published At May 26, 2023
Reviewed AtDecember 6, 2023

What Is Schizophrenia?

Childhood schizophrenia is a rare mental disorder believed to affect around one in every 40,000 children. It is a chronic and severe mental illness that causes thinking, feeling, and behavior disturbances. This disorder typically emerges between the ages of fourteen and sixteen and is characterized by an impaired ability to interpret reality. Schizophrenia can vary in severity but may include hearing voices, delusions, disorganized speech, difficulty with concentration and attention, social withdrawal, unusual or disorganized behavior, and depression. It is also associated with physical problems such as poor coordination, delayed development, and a weakened immune system. Early diagnosis and treatment are essential to improve the prognosis and quality of life for those affected. This article will discuss the latest research on childhood schizophrenia, its causes, symptoms, and treatments.

What Are the Causes of Childhood Schizophrenia?

The exact cause of childhood schizophrenia is still unknown; some experts say that the following factors are involved in the development of childhood schizophrenia:

  • Genetic Factors: Schizophrenia is often seen to run in families, indicating that genetics may play a role.

  • Environmental Factors: Stressful events and poor living conditions during childhood can increase the risk of developing schizophrenia.

  • Brain Chemistry: An imbalance in neurotransmitters like dopamine and glutamate could cause changes in the brain and lead to schizophrenia.

  • Abnormal Brain Development: It is believed that certain changes in brain structure and functioning due to abnormal development could cause schizophrenia.

  • Neurodevelopmental Factors: Certain factors during a person's developmental years, such as viral infections or other complications during pregnancy, could increase the risk of schizophrenia.

What Are the Signs and Symptoms of Childhood Schizophrenia?

Early childhood schizophrenia (sometimes called infantile schizophrenia) typically presents before five. Symptoms can include:

  • Disorganized speech and behavior.

  • A decline in development.

  • Lack of emotion.

  • Floppy arms and legs.

  • Delay in crawling, walking and talking.

  • A limp or slumped posture.

  • The long period in which they are sluggish or inactive.

  • Hallucination which a child may see things or hear voices that are not real.

  • They may also need help understanding language, abstract concepts, or interacting with peers.

Symptoms in older children include:

  • Unusual Behavior: Children with infantile schizophrenia may demonstrate behaviors that are not typical for their age, such as spinning around, standing still for long periods, rocking or banging their heads, and talking to themselves.

  • Lack of Communication: Infantile schizophrenia can cause children to be less engaged in social interactions or to have difficulty communicating effectively. They may appear to lack facial expressions, remain silent, or even refuse to speak.

  • Delusions and Hallucinations: Delusions are false beliefs, while hallucinations involve seeing or hearing things that are not there. Children with infantile schizophrenia may have both experiences, which can be frightening and disruptive to their everyday lives.

  • Sleep Disturbances: Insomnia, difficulty sleeping, and nightmares are all common symptoms of childhood schizophrenia.

  • Poor Academic Performance: Due to the disruptions caused by their symptoms, children with schizophrenia may experience difficulty concentrating in school, leading to poor academic performance.

Experts divided the symptoms of schizophrenia among children into three categories, positive symptoms, negative symptoms, and cognitive symptoms.

Positive Symptoms: They are psychotic behavior. A person is disconnected from reality during psychosis. They may include:

  1. Delusions.

  2. Hallucinations.

  3. Disorders of movement (unusual movements or behaviors).

  4. Mental disorders (unable to organize and control thinking).

Negative Symptoms: It involves disturbed behaviors and emotions and may include:

  1. Isolation.

  2. Limited or showing no emotion.

  3. Speaking little.

  4. A feeling of no pleasure in life.

  5. The problem in starting and finishing activities.

Cognitive Symptoms: The symptoms may reflect the differences in thinking and memory that may include:

  1. Trouble focusing on tasks.

  2. Difficulty in understanding and making decisions.

  3. Poor attention span.

How Is Childhood Schizophrenia Diagnosed?

The diagnosis of childhood schizophrenia requires careful assessment and observation by a mental health professional. A comprehensive diagnostic evaluation should include an interview with the child, a review of medical history, a physical examination, and laboratory tests to rule out other possible causes of symptoms such as a head injury, drug use, or thyroid disorder.

Any diagnosis must be made only after extensive testing. Generally, a diagnosis of childhood schizophrenia will not be made until the child has had at least six months of consistent symptoms, including at least two weeks of delusions or hallucinations. In addition to these criteria, the mental health professional may assess for speech disturbances, social withdrawal, odd behavior, and changes in functioning.

  • Physical Examination - When diagnosing childhood schizophrenia, a physical examination is conducted to rule out any physical health problems that could be causing the symptoms. They include taking vital signs and performing a complete neurological exam.

  • Tests and Screenings - The doctor will also look for signs of psychological distress. Tests and screenings such as an EEG (electroencephalogram), MRI (magnetic resonance imaging), or CT (computed tomography) scan may also be done to help rule out other causes of the child’s symptoms.

  • Psychiatric Evaluation - Once these tests have been completed, the doctor may refer the child to a psychiatrist or psychologist for a more thorough evaluation. During the evaluation, the professional will use standardized tests and interview the patient and parents to understand their condition better.

The doctor will look for specific criteria to diagnose schizophrenia, including delusions, hallucinations, disorganized speech, grossly disorganized or catatonic behavior, negative symptoms (such as lack of emotion and flat affect), and social and occupational functioning impairment. If these criteria are met, the diagnosis of childhood schizophrenia can be made.

How to Treat Childhood Schizophrenia?

The treatment of childhood schizophrenia includes:

1. Medications: One of the primary treatments for infantile schizophrenia is an antipsychotic medication. This medication alters the balance of chemicals in the brain and helps reduce hallucinations, delusions, disorganized thinking, and other psychotic symptoms associated with the disorder. The most common antipsychotics used to treat infantile schizophrenia are typical or first-generation antipsychotics and atypical or second-generation antipsychotics.

  • Typical or first-generation antipsychotics block dopamine, a neurotransmitter that regulates mood and thought processes. Examples of first-generation antipsychotics include Haloperidol, Fluphenazine, and Chlorpromazine.

  • Atypical or second-generation antipsychotics, such as Risperidone, Olanzapine, Aripiprazole, and Quetiapine, also block dopamine and target other brain receptors.

2. Psychotherapy: There are other treatment options available for childhood schizophrenia, such as cognitive-behavioral therapy (CBT), family therapy, and psychotherapy. CBT can help children learn new coping skills and the healthy ways to deal with their symptoms, while family therapy can help parents better support their children. Psychotherapy can help children explore the root cause of their illness and better understand themselves.

3. Life Skill Training: Specialized classes can teach the child social skills and how to complete daily tasks. They can also get advice on overcoming challenges in life or at school.

The goal of treatment for infantile schizophrenia is to manage the disorder's symptoms and help children live happy and productive lives. Finding the right combination of medication and therapies may take some time, but with patience and dedication, children with infantile schizophrenia can lead a fulfilling life.

What Are the Complications Associated with Childhood Schizophrenia?

Schizophrenia, if left untreated, can cause problems in childhood and later life. An example of these are:

  • Other mental illnesses.

  • Suicide or self-harm.

  • Drug or alcohol addiction.

  • Isolation and conflict with family and friends.

  • Legal and financial issues.

  • Having difficulty living alone, attending school, or working.

Can Childhood Schizophrenia Be Prevented?

Unfortunately, the exact cause of childhood schizophrenia is still unknown, so there is currently no way to prevent it. However, early diagnosis and treatment can help reduce the impact of this disorder on a child's life. Studies have suggested that proper nutrition, social interaction, and avoiding stress during early childhood development may help protect against certain mental health issues. Parents should pay attention to their child's development and talk to their doctor if they have any concerns.

Conclusion

Childhood schizophrenia is a complex and difficult disorder to diagnose, manage and treat. Treatment is typically tailored to the individual and may involve a combination of medications, psychotherapy, and lifestyle changes. While there is currently no known cure for childhood schizophrenia, many children can still lead fulfilling lives with appropriate support and treatment. Early intervention and support are key to managing symptoms and improving outcomes. With the help of healthcare professionals, parents, and support groups, children with schizophrenia can lead meaningful and productive lives.

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Dr. Vishal Anilkumar Gandhi
Dr. Vishal Anilkumar Gandhi

Psychiatry

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