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Riboflavin and Eye Health: An Overview

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Riboflavin supplements can help prevent cataracts, an eye condition that results in a hazy lens.

Written by

Dr. Palak Jain

Medically reviewed by

Dr. Aditi Dubey

Published At November 16, 2023
Reviewed AtNovember 16, 2023

Introduction

The development of blood vessels in the transparent covering of the eye (the cornea's vascularization) is associated with a B2 deficiency. A lack of vitamin B2 has increased the risk of age-related cataracts. One Australian study of both men and women showed that those who consumed the most riboflavin were 50 percent less likely to get cataracts than those who consumed the least riboflavin. Patients with advancing keratoconus are treated with riboflavin (vitamin B2) drops and UV (ultraviolet) light exposure.

What Is Riboflavin?

The body requires riboflavin, a water-soluble and heat-stable vitamin, to convert lipids, proteins, and carbohydrates into glucose for energy. Riboflavin increases energy and is an antioxidant for good skin, hair, and immune system function. Flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), two coenzymes, aid in the occurrence of these actions. Macronutrients, including proteins, lipids, and carbohydrates, cannot be processed and kept in balance by the body without sufficient riboflavin.

Since the body can absorb most of the nutrients from the diet with a healthy digestive system, it is critical to obtain most of the riboflavin from dietary sources. Riboflavin contains a yellow-green fluorescent pigment that turns urine yellow, suggesting the body is using it. Niacin, which stimulates vitamin B6, is produced when tryptophan is transformed into riboflavin. Anemia, cataracts, migraines, and thyroid dysfunction are avoidable disorders that may be treated with enough riboflavin.

What Are the Causes of Riboflavin Deficiency?

Usually, eating less fortified cereals, dairy products, and meat leads to riboflavin insufficiency. The likelihood of developing a riboflavin deficit is increased by:

  • Persistent illnesses (such as repeated gastrointestinal diseases, liver conditions, and persistent alcohol use disorders).

  • Malabsorption disorders like poor food absorption.

  • Both hemodialysis and peritoneal dialysis (blood-filtering techniques).

  • Long-term use of barbiturates.

What Food Sources Contain Riboflavin?

The following food sources contain riboflavin:

  • Cereals.

  • Milk.

  • Cheese.

  • Eggs.

  • Almonds.

  • Steak.

  • Salmon.

  • Chicken.

  • Broccoli

  • Fortified bread.

Does Riboflavin Prevent Cataracts?

Vitamin B2 is necessary for normal eyesight, along with other nutrients. Early research suggests riboflavin may help prevent cataracts or damage to the eye's lens that causes blurry vision. People who took a niacin and riboflavin supplement had a rare chance of getting cataracts than those who took other vitamins and minerals. Riboflavin at 400 mg/d has some protective benefits against developing age-related cataracts.

What Are Cataracts?

Opacities called cataracts develop in the eye's lens and hinder vision. They develop due to proteins in the eye aggregating because of improper three-dimensional structure. Oxidative stress and glycation are two of the many processes that lead to protein aggregation. Surgery is typically used to cure cataracts, the most prevalent cause of blindness.

Even though higher-than-normal blood glucose levels, even if not clinically termed diabetes, might lead to cataracts, many people might not be aware of this association between cataract development and diabetes. Natural treatments, including glycation inhibitors like carnosine and carnitine, and antioxidants like vitamin C and riboflavin, may help lower the risk of cataract development.

Can Supplements Improve Vision and Eye Health?

People with a family history of vision impairment or other eye health disorders can be worried that they will eventually experience similar symptoms. Nevertheless, studies suggest that food is as important as heredity in influencing eye health. To preserve or enhance eyesight, particularly as one age, the eyes need a crucial combination of vitamins. As people age, their eyesight naturally deteriorates. As the eyesight becomes increasingly hazy, it can be frightening for many individuals. Riboflavin (vitamin B2) can help reduce oxidative stress, which is good for the eyes. Chronic riboflavin deficiency, according to a study, may lead to cataracts.

How to Treat Riboflavin Deficiency?

Riboflavin supplements are available in 25 mg, 50 mg, and 100 mg tablet forms. The National Institutes of Health recommend daily riboflavin consumption:

  • Males should take 1.3 mg (milligrams).

  • Women should take 1.1 mg.

  • Male adolescents (ages 14 to 18) should take 1.3 mg.

  • Female adolescents (ages 14 to 18) should take 1.0 mg.

  • Pregnant women should take 1.4 mg.

  • Nursing women should take 1.6 mg.

  • Infants aged 0 to 6 months should take 0.3 mg.

  • Children aged 7 to 12 months should take 0.4 mg.

  • Children aged 1 to 3 years should take 0.5 mg.

  • Children aged 4 to 8 years should take 0.6 mg.

  • Children aged 9 to 13 years should take 0.9 mg.

It is critical to take riboflavin supplements with meals since absorption increases with food. Injections are an alternative if oral supplementation is not feasible.

Why Is Glutathione Important for Eye Health?

Glutathione is essential for maintaining healthy eyes and keeping the eyesight sharp as it ages. The following are five advantages of glutathione for the eyes:

1. Providing UV Damage Protection:

Glutathione can aid in shielding the eyes from harm brought on by ultraviolet (UV) light. Glutathione assists in blocking harmful UV radiation and preventing eye damage. Age-related macular degeneration (AMD) is linked to oxidative stress and inflammation, both of which can be decreased by glutathione.

2. Address Dry Eyes:

Glutathione can help with the symptoms of dry eye. Glutathione aids in lubricating and preventing dryness of the eyes.

3. May Help With Blepharitis:

Blepharitis can be treated with glutathione. Eyelid inflammation, known as blepharitis can result in burning, itching, and redness. Inflammation can be reduced, and blepharitis symptoms can be ameliorated, using glutathione.

4. Prevent Cataracts in the Eyes:

The antioxidant glutathione may help prevent cataracts in the eyes. The most prevalent age-related eye disorder that results in clouded eye lenses. Glutathione aids in preventing oxidative damage, a significant factor in cataract development.

Conclusion

Eyesight can greatly benefit from a balanced diet and lifestyle. Although eye supplements would not treat current eye issues, they can be used as a preventative approach to delay the onset of eye illness. In particular, for people who eat a balanced, nutritious diet, these eye supplements are not necessary for excellent eye health. Regarding maintaining eye health, riboflavin is undoubtedly the most crucial B vitamin. To aid in protecting glutathione, riboflavin is required. An essential antioxidant called glutathione is concentrated in the eye and is present throughout our bodies. Riboflavin consumption has been associated with a reduced risk of cataract formation.

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Dr. Aditi Dubey
Dr. Aditi Dubey

Ophthalmology (Eye Care)

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eye careriboflavin deficiency
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