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Management of Pulmonary Embolism in Emergency Medicine: An Overview

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Pulmonary embolism can be fatal if not managed immediately. Read the article to learn more about the emergency management of pulmonary embolism.

Written by

Dr. Neha Rani

Medically reviewed by

Dr. Kaushal Bhavsar

Published At December 26, 2023
Reviewed AtDecember 26, 2023

Introduction

Pulmonary embolism cases are often seen in the emergency department of a clinical health set-up. Hence, healthcare professionals need to be well-prepared to quickly diagnose and successfully treat PE in the high-stress environment of the emergency department. Emergency healthcare workers must be aware of the complexities of PE since early detection and intervention are essential for enhancing patient outcomes and saving lives. The complexity of managing PE in the emergency room will be explained in this overview, which emphasizes the need for quick and precise decision-making to address this important healthcare issue.

What Is Pulmonary Embolism?

The presence of blood clots in the blood supply of the lungs is called pulmonary embolism (PE). This occurs when a blood clot from another region of the body, usually the arm or leg, travels through the veins to the lung. A PE limits blood flow to the lungs, reduces lung oxygen levels, and raises blood pressure in the pulmonary arteries. A pulmonary embolism may result in death if not treated immediately. PE can lead to lung damage and heart failure as it increases the strain and stress on the heart. It can also result in death if the size of the blood clot is large.

What Are the Signs and Symptoms of Pulmonary Embolism?

One of the main signs of a pulmonary embolism is chest discomfort, which can be dull and heavy or severe and stabbing, throbbing, burning, or localized under the breastbone on one side. People who experience this discomfort may lean over or grip their chest, as it often gets worse when they breathe deeply. Other symptoms include low blood pressure, leg pain, redness, swelling, anxiety, dizziness, fainting, low blood oxygen levels (hypoxemia), fast breathing and heartbeat, low blood pressure, abrupt cough with possible blood in the mucus, sudden onset of shortness of breath during sleep or exertion, low-grade fever, and, in rarer cases, bluish skin (cyanosis).

What Is the Role of the Emergency Department in Managing Pulmonary Embolism?

  • Initial Assessment - When a patient presents to the emergency department (ED) with signs and symptoms that point to a pulmonary embolism (PE), such as acute chest pain, hemoptysis (coughing up blood), and shortness of breath, the medical team must prioritize assessment right once. The first step in this process is a quick assessment of vital signs, such as heart rate, to look for potential tachycardia (increased heart rate), blood pressure, evidence of hemodynamic instability, and oxygen saturation to look for indicators of respiratory distress. The clinical presentation of a patient and these early vital sign measures play a critical role in directing subsequent diagnostic and therapy choices, assuring prompt and effective management of this potentially life-threatening disease.

  • Risk Assessment - To determine a patient's risk of a pulmonary embolism (PE), healthcare providers use risk assessment methods like the Wells score and the PERC rule. These instruments support risk stratification and assist doctors in deciding if diagnostic testing is necessary. These methods help identify people who are more likely to get PE by taking into account variables such as clinical symptoms, medical history, and particular criteria. As a result, those who are more likely to develop PE receive the right diagnostic tests, while low-risk cases undergo fewer unneeded treatments. The management of suspected PE cases is optimized by this strategy.

  • Patient Stabilization - Patients with suspected or confirmed cases of PE need to be quickly evaluated for hemodynamic stability. High-risk people are those who exhibit instability symptoms, such as low blood pressure. These patients may require prompt treatment for their life-threatening illness, such as thrombolytic therapy (the use of drugs to dissolve existing blood clots or stop developing new ones) or embolectomy (the procedure of removing a blood clot (thrombus) that is impeding normal blood flow through a blood vessel). Low-risk individuals, on the other hand, can continue with additional diagnostic procedures, like imaging scans, to confirm the diagnosis and choose the best course of action, assuring a customized strategy for managing PE in each patient.

  • Diagnostic Testing - The main diagnostic procedure for pulmonary embolism (PE) is a computed tomography angiogram, which provides high-resolution images of the pulmonary arteries. A ventilation-perfusion (V/Q) scan is an imaging option to evaluate for PE when CTPA is not practical or is not recommended, such as in cases of renal impairment or dye allergies. D-dimer blood test (it detects the amount of D-dimer, a protein produced by the body to dissolve blood clots) is used in cases of pulmonary embolism.

  • Oxygen Therapy - Individuals suffering from pulmonary embolism (PE) may need more oxygen in order to maintain the oxygen level. Mechanical ventilation may be required in extreme circumstances where oxygen levels cannot be maintained by non-invasive techniques. Patients with hemodynamically unstable PE may require treatments, including fluid resuscitation (supplying fluid through intravenous means) and vasopressors to stabilize blood pressure and ensure adequate tissue perfusion. These actions are essential in high-risk PE cases to address the severe nature of their disease, promote oxygen delivery, and preserve circulatory stability.

  • Anticoagulation Therapy - Pulmonary embolism (PE) is mostly treated with anticoagulation medication. To stop clot advancement and stop the creation of new clots, anticoagulants such as low-molecular-weight Heparin or direct oral anticoagulants must be started right away. By preventing blood clot formation and reducing the chance of embolism recurrence, this treatment therapy seeks to address the underlying cause. Anticoagulants should be administered as soon as possible after a PE diagnosis to reduce morbidity and avoid potentially fatal consequences.

  • Hospital Admission - The majority of patients who are diagnosed with pulmonary embolism are admitted to the hospital for thorough monitoring, anticoagulant therapy, and further evaluation of the underlying cause. However, in the absence of significant contraindications and for low-risk patients with access to dependable follow-up care, outpatient treatment can be taken into consideration. This method enables personalized management, lower hospital stays, and lower healthcare costs while maintaining patient safety through patient oversight and sensible therapeutic approaches in low-risk PE cases.

Conclusion

Rapid identification, risk assessment, and rapid implementation of specialized treatment are essential in the setting of emergency medicine for improving results in pulmonary embolism cases. To ensure thorough patient care, a multidisciplinary strategy combining emergency physicians, pulmonologists, cardiologists, and hematologists is frequently required. The management of this potentially fatal illness is optimized by interdisciplinary teamwork, increasing the likelihood of a positive outcome.

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Dr. Kaushal Bhavsar
Dr. Kaushal Bhavsar

Pulmonology (Asthma Doctors)

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