HomeHealth articlesgastrointestinalWhat Environmental Factors Affect The Gut Microbiome?

Impact of Environmental Factors on Gastrointestinal Health

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Environmental variables can disrupt the homeostasis of gastrointestinal microbes; thermal stress and psychological stress are the most relevant.

Written by

Dr. Palak Jain

Medically reviewed by

Dr. Jagdish Singh

Published At April 5, 2024
Reviewed AtApril 9, 2024

Introduction

Numerous microbial species exist in the gut involved in food metabolism and calorie extraction; certain microorganisms are better at this process than others. Some people's microbes may collect more calories than others because they have slightly different bacterial consortia, which could make them more prone to obesity. It implies that changes in the microbiota could be a factor in the development of obesity.

Additionally, the researchers discovered that the microbiota from fat people appeared to obtain more energy from the same food than from lean people because it had more genes involved in the breakdown of carbohydrates. According to several studies, neurologic disorders may be connected to the microbiome. The microbiota may impact the nervous system at several different touchpoints.

What Exactly Are Environmental Pollutants?

1. Antibiotics

According to several studies, neurologic disorders may be connected to the microbiome. The microbiota may impact the nervous system at several different touchpoints.

The goal of antibiotic drugs is to eradicate the "bad" bacteria that are causing the patient's illness. This means that using antibiotics may alter the behavior of the microorganisms. Antibiotic use unavoidably alters the behavior of the gut microorganisms, whether they survive or not.

The medication works well to eradicate harmful bacteria but also hurts beneficial bacteria. Antibiotic usage regularly will change the gut flora's population balance and impact the microbiome's general health. Changes in the gut microbiome potentially upset the delicate equilibrium between the immune system and gut bacteria, leading to some immunological disorders.

The impacts on the gut flora may linger for several years. The gut microbiota may become dysbiotic as a result of antibiotic use. Antibiotic resistance, which lowers the medication's efficacy, can also result from long-term usage. Antibiotics heal bacterial diseases, which is a crucial fact to know. They kill no viruses. To address a pertinent health issue, confirm with the physician if they are prescribed antibiotics. Prescription drugs that stress the stomach should not be taken carelessly.

2. Nanoparticles and Food Additive

Modern manufacturers add nanomaterial nanoparticles (NPs) to food, cosmetics, and nutritional items. These materials are minuscule and microscopic. These ingredients are not the active ones; they are just helpers. They can enter the human body through ingestion, inhalation, or skin penetration and may serve as a binder in supplement capsules or whitened toothpaste.

Cosmetics, dietary supplements, and some pharmaceuticals include nanoparticles, a recently discovered environmental hazard. Nanoparticle safety and how these pollutants harm the gastrointestinal tract are issues that need to be addressed. Through both oral and non-oral routes, nanoparticles may impact the gut microbiome. Emulsifiers are among the substances used in processed foods as food additives to extend their shelf life. Their detrimental effects on gut microbiota and intestinal tissue integrity have been demonstrated. Increase the intake of whole, fresh meals free of these harmful ingredients.

What Environmental Factors Affect the Gut Microbiome?

Nutrients, contaminants, pests, and weeds all impact the gut microbiota. It is also impacted by the diversity of plants and their various life cycles or seasons.

1. Diet

A diversity of plant fibers is necessary for the diversity of microorganisms that comprise the gut microbiome. Preferred complete foods vary throughout organisms. As a result, they create byproducts like short-chain fatty acids that feed the gut and bring down its pH, which is ideal for the more advantageous bacteria.

However, a diet rich in sugar and fatty fats favors the less beneficial kinds of microbes. Foods that have been processed often have an abundance of chemicals and preservatives that might be detrimental to the microbiota, in addition to being low in fiber and micronutrients (such as vitamins and minerals).

2. Chemicals

Environmental poisons such as alcohol, tobacco smoke, and pollution have the potential to harm the microbiome. Pesticides and antibiotics have the added ability to eradicate both beneficial and bad microorganisms. Acid blockers are among the other drugs that can alter the pH inside the microbiota. Temporary chemical exposure, such as a brief prescription for a medication required to get well, normally does not harm the gut flora. Prolonged exposure, however, can change its makeup. Certain microorganisms may not be able to flourish in an individual if they regularly consume alcohol or take certain drugs.

3. Diversity

Several kinds of bacteria help each other out in a healthy gut microbiome.

Conversely, an unbalanced microbiome that lacks a diverse range of beneficial microbes is more susceptible to invasion by pathogenic varieties. These "weeds" and "pests," in the absence of healthy competition, take over the environment and exhaust the resources required for the other species to survive.

What Should One Change in Their Environment to Benefit the Gut Microbiota?

  • It is increasingly believed that complex illnesses traditionally linked to lifestyle are caused by the microbiome. Rethinking antacids, H2 antagonists, and proton pump inhibitors (PPIs) will promote gut health because the gut flora is so sensitive to medication. In general, long-term usage of these drugs prescribed for gastrointestinal disorders such as GORD/GERD is not advised.

  • Gastro-oesophageal reflux disease is a complicated illness. Although lifestyle behaviors were once thought to be the cause, experts now believe that bacteria play a role.

  • Reducing contaminants will lessen the influence of the environment on the gut flora, including pesticides, nanomaterials, food additives, and medications. Additional dietary and lifestyle adjustments will help reduce the principal contaminants that impede gut health.

  • Nutritional care offers easy ways to improve the environment of the gut microbiota and balance the gut flora.

Conclusion

Various symbiotic bacteria live and are harbored in the human body's intestines. In a state of harmonic symbiosis with the body, the makeup of the gut flora is largely consistent under normal conditions. More importantly, as a massive community in the intestines, the microbiota plays a pleiotropic function in human health and disease. On the one hand, it helps with food digestion and nutritional absorption. The gut microbiome will be less affected by the environment if contaminants such as pesticides, nanomaterials, food additives, and medications are reduced. Making more dietary and lifestyle adjustments will help reduce the main contaminants that impede gut health.

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Dr. Jagdish Singh
Dr. Jagdish Singh

Medical Gastroenterology

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