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Hypercholesterolemia - Types, Symptoms, Causes, Diagnosis and Treatment

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High cholesterol has quietly become one of the major contributors to serious health problems and deaths in recent years.

Medically reviewed byDr. Rajiv Kumar Srivastava
Published At October 9, 2021
Reviewed AtFebruary 5, 2026

What Is Cholesterol?

Cholesterol is a fatty, wax-like substance that is naturally present in the body and circulates in the bloodstream. It plays an essential role in making hormones, producing vitamin D, and forming bile acids. This substance helps the body digest and absorb food.

Cholesterol is a fatty substance in the body and bloodstream. The liver makes most of the cholesterol the body needs. Cholesterol is also taken in through foods such as meat, eggs, dairy products, and oily foods. However, too much cholesterol in the blood can cause health problems.

Why Is Too Much Cholesterol Harmful?

Cholesterol is not harmful when it stays within healthy limits. The problem begins when its levels rise beyond what the body needs. Excess cholesterol starts depositing along the inner walls of blood vessels, forming fatty plaques.

With time, cholesterol deposits will narrow the vessels, restrict blood flow, and cause issues. If left untreated, this process can turn high cholesterol into a health risk.

What Is Hypercholesterolemia?

Hypercholesterolemia means a person has higher-than-normal cholesterol levels in their blood. It develops gradually, often without any specific warning signs.

Many people are unaware of the condition until they undergo a blood test. If cholesterol levels remain high for a long time, it can damage blood vessels.

What Are the Different Types of Cholesterol?

  • Total Cholesterol: Shows the overall amount of cholesterol present in the blood.

  • High-Density Lipoproteins (HDL): These are termed good cholesterol. They are protective against heart disease and stroke. They help reduce bad cholesterol levels by carrying them from the arteries to the liver. Having high levels of HDL can prevent heart disease.

  • LDL (Bad Cholesterol): High LDL levels are associated with an increased risk of heart disease and stroke. The LDL (bad cholesterol) builds up in the inner walls of the arteries and remains as fatty deposits (known as plaque). These plaques make the arterial passage narrow, thereby obstructing the blood flow.

  • VLDL (Very-Low-Density Lipoprotein): These are also a type of low-density lipoprotein that is bad for health. The higher the VLDL level, the higher the risk for heart problems. These carry triglycerides.

These cholesterol levels are usually checked through a blood test called a lipid profile.

What Are Triglycerides?

Triglycerides are a type of fat found in the blood. They are formed when the body stores extra calories from food. High triglyceride levels often occur due to overeating, lack of exercise, or obesity. Elevated triglycerides increase the risk of heart disease. When combined with high LDL or low HDL, the danger becomes greater. Triglyceride levels are routinely measured along with cholesterol.

What Symptoms Does High Cholesterol Cause?

High cholesterol usually causes no symptoms at all. Most people feel completely normal despite having high levels. Because of this, it is often called a silent condition. Many people discover it only during routine blood tests. Sometimes, the first sign may be a serious event like a heart attack or stroke. Regular screening is the only way to detect it early.

What Causes High Cholesterol?

  • Eating unhealthy foods, especially those high in fats, oils, and fried items.

  • Lack of regular physical activity or exercise.

  • Being overweight or obese.

  • Smoking lowers good cholesterol and damages blood vessels.

  • Diabetes can increase bad cholesterol levels.

  • Thyroid disorders, especially low thyroid function.

  • Hormonal conditions like PCOS (polycystic ovarian syndrome).

  • Kidney or liver diseases.

  • Family history or inherited tendency for high cholesterol.

What Health Problems Can High Cholesterol Cause?

  • When a person has high cholesterol, it builds up in blood vessels, reducing blood flow to organs.

  • Blocked arteries will eventually cause heart issues (chest pain or heart attack).

  • Poor circulation can also affect limbs and sexual function. These complications develop slowly but can be life-threatening.

What Is Familial Hypercholesterolemia?

Familial hypercholesterolemia is an inherited condition passed down through families. People with this condition have very high bad cholesterol from a young age. The body cannot remove LDL cholesterol effectively. As a result, cholesterol builds up early in life. This greatly increases the risk of early heart disease. Such individuals require early diagnosis and long-term treatment.

How Is High Cholesterol Diagnosed?

  • It can be diagnosed with the help of blood tests.

  • The blood test measures total cholesterol, LDL, HDL, and triglycerides.

  • Blood is usually taken after fasting (usually eight hours) for accurate results.

  • Adults above 20 years should check their cholesterol at least once every five years.

  • More frequent testing is advised for high-risk individuals.

How Is High Cholesterol Treated?

Treatment depends on how high the cholesterol levels are. Mild cases can often be controlled with lifestyle changes. Doctors may advise a healthy diet, regular exercise, and weight control. Smoking cessation is strongly recommended. If lifestyle changes are not enough, medicines such as statins may be prescribed. Medicines should always be taken as advised by a doctor.

How Can High Cholesterol Be Prevented?

  • High cholesterol can be prevented by following healthy habits.

  • You must eat a balanced meal.

  • The diet must be complete with fruits, vegetables, and whole grains.

  • Regular physical activity improves good cholesterol levels.

  • Avoid fried and processed foods

  • Maintaining a healthy weight reduces the risk of heart disease.

  • Regular blood tests are needed to detect high cholesterol.

Conclusion

High cholesterol levels are common these days because of a sedentary lifestyle. As it usually does not cause symptoms, many people are unaware of it.

High cholesterol levels that are not treated can lead to serious heart-related problems. However, with appropriate treatment and healthy lifestyle choices, high cholesterol can be managed and controlled. If you have high cholesterol levels or need guidance, consult an expert physician.

Key Takeaways

  • High cholesterol usually does not cause any noticeable symptoms, but over time, it can quietly damage the heart and blood vessels, increasing heart disease and stroke risk.

  • Unhealthy lifestyle habits and certain medical conditions are common causes of high cholesterol.

  • Adopting a regular exercise, healthy diet, and medical treatment at the right time can help reduce your cholesterol levels.

Frequently Asked Questions

Hypercholesterolemia is most commonly caused due to intake of more saturated and trans fats, smoking, alcohol intake, poor dietary habits, lack of exercise, etc.
The best treatment for hypercholesterolemia is having a healthy fiber-rich diet, doing regular exercise, taking statins and selective inhibitors of cholesterol, etc.
The other name for high cholesterol in the body is hypercholesterolemia. Hence hypercholesterolemia and high cholesterol are both the same and are defined as increased cholesterol levels in the body.
A heart-healthy dietary habit helps in reducing the cholesterol level in the body. Some of the foods that help in reducing cholesterol are oats, beans, fatty fish, nuts, etc.
A condition is considered a disability if it prevents the individual from performing a gainful activity. Hypercholesterolemia is not a disability as it will not prevent the individual from performing gainful activities.
Cholesterol levels can be reduced quickly by having a good diet including fruits, vegetables, beans, whole grains, and protein-rich foods and decreasing the intake of refined grains, processed foods, and fat (especially animal fats).
Hypercholesterolemia can run in the family. In that case, it is known as familial hypercholesterolemia. It is caused due to genetic mutation, which results in hampering the body's ability to regulate and remove cholesterol from the blood.
Hypercholesterolemia leads to the deposition of cholesterol in the blood vessels, which might lead to blockage of blood vessels resulting in heart problems, stroke, etc.
Pure hypercholesterolemia, alias familial hypercholesterolemia, is a condition where high cholesterol is caused due to genetic mutation. The mutation of the gene affects the body’s ability to regulate and remove cholesterol from the blood.
Yes, familial hypercholesterolemia can be controlled naturally by having a heart-healthy diet and regular exercise. A diet with a reduced intake of cholesterol and saturated fat is beneficial.
Certain types of hypercholesterolemia are curable, but familial hypercholesterolemia can only be treated and cannot be cured completely.
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