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Human Milk Microbiome - Origin, Function, Uses, and Importance

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Human milk microbiome or human milk probiotics that encompasses significant bacteria. The importance of microbiota is revealed in this article.

Written by

Dr. Sanchana. N

Medically reviewed by

Dr. Veerabhadrudu Kuncham

Published At September 12, 2023
Reviewed AtSeptember 12, 2023

What Is Human Milk Microbiota?

Human Milk Microbiota is otherwise called human milk probiotics. The human milk microbiota refers to the microorganisms that are present in human breast milk. These microorganisms include bacteria, fungi, viruses, and other microorganisms that play an essential role in the development of the infant's gut microbiome.

How the Microbiota Originated?

Human milk microbiota is a complex composition of bacteria, fungi, and viruses that are transferred from the mother to the infant during breastfeeding.

The origin of microbiota found in human milk is thought to be from three main sources:

  • The mother's skin.

  • The mother's oral cavity.

  • The infant's microbiota.

The microbiota found in the mother's skin is transferred to the milk during the process of milk production. In contrast, the microbiota from the mother's oral cavity is transferred to the milk through the mammary gland.

The infant's microbiota is transferred to the milk through direct contact with the mother's skin or the infant's skin. It is believed that the microbiota in human milk is crucial for the growth of the infant's immune system and gut microbiome.

What Are the Functions of Microbiota?

The importance of the human milk microbiota lies in the fact that the composition of the microbiota in breast milk is different from that found in other sources of nutrition, such as infant formula. Human milk is rich in beneficial microorganisms that can influence the development and diversity of the infant's microbiome, which can affect the baby's health and immune system.

There are several functions of the human milk microbiota, including:

  • Immunomodulation: The human milk microbiota has been found to play a significant role in modulating the infant's immune system. The microbiota in breast milk may help protect against infections, promote immune system development, and reduce the risk of allergies and autoimmune diseases.

  • Digestion and Metabolism: The microorganisms in human milk may also aid the digestion and metabolism of breast milk, helping to ensure the infant receives adequate nutrition.

  • Protection Against Pathogens: The human milk microbiota contains beneficial microorganisms that can compete with and reduce the growth of potentially harmful microorganisms within the infant's gut.

  • Development of the Gut Microbiome: The presence of beneficial microorganisms in human milk can help shape and establish the infant's gut microbiome, leading to long-term benefits in health and disease prevention.

What Are the Factors That Influence Microbiota?

The microbiota is the collective name for the microorganisms that inhabit the human body. It is estimated that there are 10 times more microbes in the human body than human cells. Several factors influence the composition of the microbiota, which is important for maintaining bodily health.

  • One of the most crucial elements in determining the microbiota's makeup is diet. Studies have demonstrated that fiber-rich meals, including those found in plant-based diets, can encourage the development of healthy bacteria in the gut. Conversely, diets high in processed foods and animal products can lead to an imbalance in the microbiota, which can lead to health issues.

  • The environment also plays a role in influencing the microbiota. For instance, exposure to specific toxins or chemicals might change the gut microbiota's composition. Similarly, the use of antibiotics can disrupt the balance of the microbiota, leading to dysbiosis.

  • An individual's age is also a factor in determining the composition of their microbiota. It is thought that the microbiota of infants is composed of bacteria that are transferred from their mothers. As the infant grows, their microbiota begins to diversify and is further shaped by their environment and diet.

  • Finally, the use of probiotics and prebiotics can also influence the composition of the microbiota. Probiotics are living microorganisms that can aid in re-establishing the microbiota's delicate equilibrium. Prebiotics are non-digestible carbohydrates that can promote the growth of beneficial bacteria.

In summary, microbiota is an important part of the human body, and a variety of factors influence its composition. Diet, environment, age, and the use of probiotics and prebiotics are all factors that can shape the composition of the microbiota. Understanding these factors can help to promote healthy microbiota and improve overall health.

What Are the Uses of Human Microbiota?

These microorganisms play an important role in the production and ripening of dairy products They are capable of being put to several uses.

1) Probiotic Yogurt:

  • The most common use of milk microbiota is in the production of probiotic yogurt and other fermented dairy products.

  • Probiotic bacteria, such as Lactobacillus and Bifidobacterium, are often added to milk to promote the growth of beneficial microbes that can help to improve gut health.

  • Additionally, yogurt's probiotic bacteria can aid in better dairy product digestion and potentially lower the chance of contracting some diseases.

2) Fermented Beverages:

Milk microbiota can also be used to produce fermented beverages such as kefir, a traditional drink made from fermented milk. Kefir is said to have numerous health benefits, including improved digestion and increased energy levels.

3) Bioplastics:

  • Another potential use of milk microbiota is to produce bioplastics. Bioplastics are plastics made from natural sources such as plant matter and are a more sustainable alternative to traditional petroleum-based plastics.

  • Lactose, a milk sugar, may be transformed by milk microbiota into lactic acid, which can then be utilized to make bioplastics.

4) Enzymes and Proteins:

Finally, milk microbiota can be used to produce a variety of enzymes and other proteins. These proteins can be used in a variety of applications, such as food processing, wastewater treatment, and bioremediation.

Conclusion

In conclusion, the microbiota in human milk is essential for newborns' proper growth and development. It plays significant roles in the immune system, digestion, and metabolism and helps to establish a diverse and healthy gut microbiome that can provide long-term health benefits. The milk microbiota has the potential to be used for a variety of purposes, including the production of probiotic yogurt and other fermented dairy products, the production of bioplastics, and the production of enzymes and other proteins. These applications could have a significant impact on the sustainability of food production, as well as on the health of individuals.

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Dr. Veerabhadrudu Kuncham
Dr. Veerabhadrudu Kuncham

Pediatrics

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