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Psoriasis in Pregnancy - Revealing the Link

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Managing psoriasis during pregnancy is crucial in pregnant women. Read the article to know more about it.

Written by

Dr. Aparna Arun

Medically reviewed by

Dr. Dhepe Snehal Madhav

Published At March 18, 2024
Reviewed AtMarch 18, 2024

Introduction

Psoriasis, a chronic autoimmune condition characterized by the rapid accumulation of skin cells, can present unique challenges for pregnant individuals. Pregnancy is a time of immense physical and hormonal changes, and for those with psoriasis, these changes can significantly impact their condition. Understanding how pregnancy influences psoriasis and how to effectively manage it during this critical time is essential for both the well-being of the mother and the baby.

What Is Meant by Psoriasis?

Psoriasis is a persistent immune system-related inflammatory condition that impacts around three percent of the population. It manifests as red, raised, scaly patches on the skin, often accompanied by itching, burning, or discomfort. Psoriasis has been associated with various other health issues, including diabetes, depression, and cardiovascular disease. Factors such as stress, skin injuries (such as sunburns, bites, or scratches), certain medications, and infections can all potentially trigger flare-ups of psoriasis, including those caused by strep throat or respiratory infections. Allergies, dietary habits, and weather conditions are among the potential factors contributing to psoriasis flare-ups. However, what triggers flare-ups in one individual may not necessarily affect another individual with psoriasis.

What Are the Impacts of Pregnancy on Psoriasis?

Pregnancy can have varying effects on psoriasis, depending on the individual. Some pregnant individuals may experience improvements in their psoriasis symptoms, while others may notice exacerbations. Understanding these impacts is essential for effective management during pregnancy. Here are some common ways pregnancy can influence psoriasis:

  • Improvement in Symptoms: Some pregnant individuals with psoriasis may experience a temporary remission or significant improvement in their symptoms during pregnancy. This improvement is often attributed to hormonal changes, particularly increased levels of estrogen, which can have anti-inflammatory effects on the skin. As a result, skin lesions may become less pronounced, and itching and redness may decrease.

  • Worsening of Symptoms: Conversely, some pregnant individuals may notice that their psoriasis symptoms worsen during gestation, particularly in the first trimester. This exacerbation is thought to be related to fluctuations in hormone levels, stress, and immune system changes that occur during pregnancy. Psoriasis flare-ups during pregnancy can be challenging to manage, as certain treatment options may be limited due to potential risks to the baby.

  • Increased Risk of Complications: While psoriasis itself does not directly cause complications during pregnancy, certain factors associated with the condition may pose risks. For example, individuals with severe psoriasis or those who require systemic medications to manage their symptoms may face challenges in finding safe treatment options during pregnancy. Additionally, psoriasis has been associated with an increased risk of some pregnancy complications, like preterm birth and low birth weight. Pregnant individuals with psoriasis need to be in contact continuously with their healthcare providers to identify any potential complications and manage them accordingly.

  • Psychological Impact: The visible nature of psoriasis can cause significant distress for pregnant individuals, affecting their self-esteem and mental well-being. This psychological impact may be heightened during pregnancy, a time when individuals may already be feeling vulnerable due to the emotional and physical changes during gestation. Pregnant individuals with psoriasis need to seek support from healthcare providers, counselors, or support groups to address any emotional challenges they may face.

  • Postpartum Considerations: For some individuals, psoriasis symptoms may improve or worsen following childbirth. Hormonal changes, stress, and changes in medication or treatment routines can all influence the course of psoriasis postpartum. New parents with psoriasis need to continue working with their healthcare specialists to manage their condition effectively during this transition period.

What Impact Does Psoriasis Have on the Baby?

  • Multiple studies indicate that women with severe psoriasis are at a higher risk of delivering babies with low birth weight compared to women with mild psoriasis or those without chronic skin conditions. Conversely, other studies have found that women with psoriasis do not experience adverse pregnancy outcomes.

  • Individuals with a family history of psoriasis have an increased risk of developing the condition by themselves. Scientists suggest that if one parent has psoriasis, there is a 10 % probability that their child will also develop the condition.

  • Yet, when both parents have psoriasis, the likelihood of the child inheriting the condition rises to approximately 50 %. Nonetheless, individuals need exposure to certain external stimuli or triggers to be susceptible to experiencing an outbreak.

  • If individuals are dealing with psoriasis, there is no need to fret over the possibility of their baby inheriting it. However, it is crucial to inform the doctor about their medical history after childbirth and maintain regular wellness checkups. This ensures that the doctor can monitor the baby for any potential signs or symptoms of the disorder.

What Are the Methods for Managing Psoriasis During Pregnancy?

The treatment options for psoriasis during pregnancy will depend on the severity of the condition. Some potential choices include:

  • Topical Treatments: For pregnant women with psoriasis affecting less than five to ten percent of the body, topical treatments such as lotions or creams applied directly to the skin, emollients like petroleum jelly, moisturizers, or low-dose topical corticosteroids are preferred treatment options. Following the daily shower, apply a generous moisturizer layer to nourish the skin. If the doctor recommends topical corticosteroids, apply a small amount only to a limited area of the skin.

  • Phototherapy: UVB phototherapy, a form of light therapy that reduces inflammation responsible for skin symptoms, is the recommended treatment when psoriasis is more severe and topical medications alone are insufficient. If UVB light therapy is not feasible for individuals, natural sunlight can serve as a beneficial alternative to help alleviate symptoms and promote well-being. Phototherapy may reduce folate levels, so it is important to ensure that they are receiving sufficient folic acid through their prenatal vitamins and consult the doctor about the necessity of additional supplementation.

  • Systemic Medications: Most pregnant women with psoriasis can be managed with topical treatments or phototherapy, although severe cases may necessitate medication. Given that not all psoriasis medications are safe during pregnancy, the healthcare providers will carefully select those posing minimal risk to both the mother and the fetus. Options like TNF (tumor necrosis factor) inhibitors such as Adalimumab and Infliximab (with dosage adjustments required before the third trimester) or Cyclosporine may be considered, despite the potential for preterm delivery and low birth weight. However, medications like Methotrexate, Acitretin, and Tazarotene are contraindicated due to their association with birth defects and miscarriage.

Conclusion

Pregnancy can be a challenging time for individuals living with psoriasis, but with careful management and support, it is possible to navigate this period successfully. By working closely with healthcare providers, implementing effective treatment strategies, and prioritizing self-care, pregnant individuals with psoriasis can minimize symptoms and optimize their health and well-being for themselves and their babies.

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Dr. Dhepe Snehal Madhav
Dr. Dhepe Snehal Madhav

Venereology

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