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Carbon Tetrachloride Poisoning - Harmful Effects, Diagnosis, and Treatment

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Learn how carbon tetrachloride, in chemicals, can cause severe poisoning if ingested or inhaled. Read about its effects, diagnosis, and treatment.

Written by

Dr. Vandana Rai

Medically reviewed by

Dr. Kaushal Bhavsar

Published At October 30, 2023
Reviewed AtOctober 30, 2023

Introduction:

Carbon tetrachloride (tetrachloromethane) is a chemical compound with the formula CCl4. It is a colorless, sweet-smelling liquid used as a solvent for various chemicals and was once widely used as a fire extinguisher. Carbon tetrachloride is a non-flammable liquid that is not easily ignited, which makes it an effective fire suppressant.

However, carbon tetrachloride has been banned due to its harmful effects on human health and the environment. The International Agency for Research on Cancer (IARC) has classified carbon tetrachloride as a probable carcinogen. The United States Environmental Protection Agency (EPA) lists it as a hazardous air pollutant.

How Does Carbon Tetrachloride Contaminate Air and Soil?

Carbon tetrachloride is not found naturally in the environment and is not produced by living organisms. However, it has been released into the environment by human activities. There are several sources of air and soil contamination with carbon tetrachloride. Some potential sources of air contamination include:

  • Industrial Processes: Carbon tetrachloride can be released into the air as a byproduct of industrial processes, such as producing chlorofluorocarbons (CFCs) and manufacturing pesticides.

  • Accidents and Spills: Carbon tetrachloride can be released into the air through accidents or spills, such as transportation accidents or spills at storage facilities.

  • Landfills: Carbon tetrachloride can be released into the air from landfills where it has been disposed of improperly.

  • Improper Disposal: Carbon tetrachloride can be released into the air through improper disposal of chemical products, such as burning or other forms of waste management.

Who Is at Risk of Carbon Tetrachloride Toxicity?

Anyone exposed to high levels of chemicals can be at risk of carbon tetrachloride toxicity. Certain individuals may be more vulnerable to the harmful effects of carbon tetrachloride toxicity.

  • Workers In Certain Industries: Individuals employed in industries that handle or produce carbon tetrachlorides, such as chemical manufacturing, dry cleaning, rubber production, and fire suppression, may be at increased risk of exposure to the chemical.

  • People Living Near Industrial Facilities: People who live near industrial facilities that use or produce carbon tetrachloride may be at a higher risk of exposure to the chemical through air or water contamination.

  • People Using Products Containing Carbon Tetrachloride: Carbon tetrachloride was once used in some consumer products, such as spot removers, dusting sprays, and cleaning agents. People who use these products may be at a higher risk of exposure to the chemical.

  • Children and Pregnant Women: Children and pregnant women are more vulnerable to the harmful effects of carbon tetrachloride due to their developing bodies and may be more at risk of toxicity.

What Are the Harmful Effects of Carbon Tetrachloride Poisoning?

Carbon tetrachloride exposure can cause various acute and chronic health effects when ingested, inhaled, or absorbed through the skin.

Acute effects of carbon tetrachloride poisoning can occur within hours or days of exposure and can include the following:

  • Nausea and vomiting.

  • Headache.

  • Dizziness.

  • Confusion.

  • Loss of consciousness.

  • Seizures.

  • Difficulty in breathing.

  • Chest pain.

  • Rapid heartbeat.

  • Low blood pressure.

  • Skin irritation or burns.

Chronic effects of carbon tetrachloride poisoning can occur after long-term or repeated exposure and can include the following:

  • Damage to the liver and kidneys.

  • Damage to the immune system.

  • Cognitive impairments, including memory loss and difficulty with concentration.

  • Damage to the nervous system.

  • Reproductive problems.

  • Cancer (International Agency for Research on Cancer has classified carbon tetrachloride as a human carcinogen).

How to Diagnose Carbon Tetrachloride Toxicity?

A healthcare provider will ask about the exposure and seek the underlying medical history to diagnose carbon tetrachloride toxicity. Exposure history includes environmental and occupational carbon tetrachloride exposure risks.

Environmental Exposure Includes:

  • Type of water supply.

  • Location and duration of residence.

  • Proximity to industry or sites.

Occupational exposure history includes:

  • Name and location of the company.

  • Job title.

  • Description of the chemical process used.

  • History of worker's illness.

  • Proper use of personal protective equipment.

Medical history should include assessments of current and past diagnoses or symptoms of:

  • Neurologic (Brain)

  • Hepatic (Liver)

  • Renal (Kidney)

  • Dermatologic diseases (Skin).

What Are the Physical Examinations Done to Assess Carbon Tetrachloride Toxicity?

During a physical examination for carbon tetrachloride poisoning, the doctor checks for the following:

  • Vital signs, including heart rate, blood pressure, temperature, and respiratory rate.

  • Signs of dehydration, such as dry mouth and skin, and any physical injuries that may have occurred during the exposure.

  • The person's eyes, nose, and throat for irritation, redness, or any symptoms of allergic reactions.

  • Abnormal sounds may indicate lung damage or other respiratory issues.

  • Specific tests may be conducted to assess the person's reflexes, muscle strength, and balance to determine the extent of neurological damage.

  • Ability to see, hear, and smell to assess any potential sensory impairments.

What Is the Treatment for Patients Exposed to Carbon Tetrachloride?

  • Removing the Person From the Source of Exposure: If the person is still in the area where they were exposed to carbon tetrachloride, it is important to remove them from the source of exposure as quickly as possible to prevent further exposure.

  • Providing Supportive Care: Depending on the person's symptoms, they may need supportive care to manage and prevent complications. This may include administering oxygen to help them breathe, fluids to prevent dehydration, and medications to control nausea and vomiting.

  • Administering Medications: If the person is experiencing severe symptoms, such as difficulty in breathing or an irregular heartbeat, they may need medications to help manage these symptoms. For example, they may be given medications to open their airways or to stabilize their heartbeat.

  • Dialysis: Severe carbon tetrachloride poisoning may require dialysis. This medical procedure uses a machine to remove waste and excess fluid from the blood and the poison from the body.

  • Providing Counseling: Carbon tetrachloride poisoning can be a traumatic experience. The person may benefit from counseling to help them cope with their emotions and any anxiety or stress they may be experiencing.

Overall, the goal of treatment for carbon tetrachloride poisoning is to manage the person's symptoms and prevent complications. If someone has been exposed to carbon tetrachloride, it is important to seek medical attention as soon as possible. Carbon tetrachloride is a toxic chemical that can have serious health effects, and prompt treatment is essential to minimize the risk of long-term complications.

Conclusion:

Carbon tetrachloride is a toxic chemical that can harm the human body. Short-term exposure to high levels of carbon tetrachloride can cause dizziness, headaches, and nausea. However, long-term exposure can lead to more serious health problems, such as liver damage, kidney damage, and even death. It is essential to use caution when handling carbon tetrachloride and to follow proper safety protocols to avoid exposure. If an individual has been exposed to carbon tetrachloride, they should seek medical attention immediately.

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Dr. Kaushal Bhavsar
Dr. Kaushal Bhavsar

Pulmonology (Asthma Doctors)

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