Q. What can be the reason for the loss of subcutaneous fat?

Answered by
Dr. Atul Sardar Narayankar
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on May 21, 2017 and last reviewed on: Sep 23, 2021

Hi doctor,

I am losing subcutaneous fat from the thighs, legs, hands, palms, foot soles, face, chest, etc. I also have some swollen nodes. I am not diabetic, my fasting blood sugar is between 100 to 107 mg/dL and postprandial is between 110 to 120 mg/dL. But, when I start losing fat, then the fasting blood sugar becomes 133 mg/dL and postprandial becomes 154 mg/dL. After taking Surbex Gold tablet, it came back to 110 and 139 mg/dL. What may be the reason for the loss of subcutaneous fat?



Welcome to

  • The subcutaneous fat loss can be a part of acquired lipodystrophy. It is a very rare condition but can be associated with some autoimmune diseases, or after any infection.
  • This condition is usually related to deranged lipid profile.
  • Consult an endocrinologist for a metabolic profile.
  • I suggest you take food containing low carbohydrates.
  • Get your blood pressure and lipid profile checked, if they are highly deranged, then you might require antilipidemics.

Revert with more information to an internal medicine physician online -->

Hello doctor,

Thank you for replying. My total cholesterol is 225, triglyceride is 106, HDL is 40, LDL is 164, VLDL is 21, bilirubin is 1 mg/dL, SGOT is 22, SGPT is 30, alkaline phosphate is 126, serum total protein is 7.3, serum albumin is 3.7, globulin is 3.6, and A/G ratio is 1.0/1. If it is acquired lipodystrophy, is there any treatment?



Welcome back to

  • There is no specific treatment for acquired lipodystrophy.
  • You need to consult a dietician and an endocrinologist. Leptin replacement has been tried, but not commonly used.

For more information consult an internal medicine physician online -->

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