My brother get tremors in hand and legs after taking antidepressants. Why?

Hello,

Welcome to icliniq.com.

I read your query and understand your concerns. First of all, I would like to inform you that three months are generally enough for the antidepressants to show effects.

Secondly, 60 mg of Fluoxetine is generally a sufficient dose for antidepressant purposes. Considering the fact, that there is some response despite the presence of adequate dose for sufficient time indicates the possibility of partial response.

Thirdly, the above observation is not unique as problems are often encountered in patients with long duration of untreated illness.

Now regarding the tremors, I think Divalproex is likely to cause tremors as a common side effect. In my opinion, 250 mg of Divalproex has a little role on this day as his aggressive behavior already reduced.

Regarding the next course of action, I feel adding another antidepressant is the first option. In case there are reasons for not doing the same adding low dose antipsychotics can be used provided there is aggressive behavior still present. I often prefer low doses of Olanzapine 5 mg to boost up the effect of Fluoxetine. I must assure you that over a period of time he will improve further.

I hope this helps.