Can I take antihistamines (an OTC drug) when pregnant?

Hi,

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Antihistamines are used to treat allergy symptoms. We have two generations of antihistamines:

First generation antihistamines like Chlorpheniramine, Dimenhydrinate, Diphenhydramine, Doxylamine are considered safe to use during pregnancy. These medications have a sedative effect (cause sleepiness).

The newer non-sedating antihistamines like Cetirizine, Desloratadine, Fexofenadine, and Loratadine are best avoided in pregnancy as we have no strong evidence confirming its safety in pregnancy.

Hope this helps.

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