My sister is suffering from bipolar disorder for the last 10 years and is presently in stable condition with Olanzapine 2.5 mg and Dicorate 250 mg one tablet each per day during night. However, recently she came to know about her pregnancy and her doctor asked her to check with a psychiatrist if she can continue her bipolar medication or not. If not, what is the alternative treatment?
Welcome to icliniq.com.
First of all, I would like to inform you that Dicorate (Divalproex sodium) should be avoided as far as possible during pregnancy. This is because of neural tube defects caused in offspring during pregnancy. The above statement is very important during the first trimester of pregnancy. I would also like to inform you that Olanzapine is largely safe during pregnancy and there is no data supporting any adverse effect of Olanzapine during pregnancy. Considering the above facts, I feel increasing the dose of Olanzapine and stopping of Dicorate is the possible strategy for your sister.
Since the increase or decrease in dose depends on multiple factors (body weight, previous episodes, response to medications, the severity of episodes, number of episodes, family history), it is not possible for anyone (including me) to speculate effective dose for an individual patient without examining all relevant factors. I request you to see her psychiatrist along with your sister for a final opinion.
For more information consult a psychiatrist online --> https://www.icliniq.com/ask-a-doctor-online/psychiatrist
Was this answer helpful?|
Query: Hello doctor, Since I was around 8 years old, I have experienced mood fluctuations but not in the normal bipolar way (which I am being tested for). I do not feel like my mood sways between depression and mania. It is always some level of mania but without depression. I also experience tactile hallu... Read Full »
Query: Hi doctor, I am six weeks pregnant. I have struggled with GERD and esophagitis for years and my gastroenterologist put me on Nexium, which is the only thing that helps. I usually do a two-week treatment every year. My pregnancy is exacerbating the GERD. I just finished a two-week Nexium treatment a... Read Full »
Ask your health query to a doctor online?Ask a Psychiatrist Now