Q. Can Olanzapine and Dicorate be continued in pregnant woman with bipolar disorder?

Answered by
Dr. Ashok Kumar Choudhary
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Mar 28, 2018 and last reviewed on: Oct 09, 2018

Hello doctor,

My sister is suffering from bipolar disorder for the last 10 years and is presently in stable condition with Olanzapine 2.5 mg and Dicorate 250 mg one tablet each per day during night. However, recently she came to know about her pregnancy and her doctor asked her to check with a psychiatrist if she can continue her bipolar medication or not. If not, what is the alternative treatment?



Welcome to icliniq.com.

First of all, I would like to inform you that Dicorate (Divalproex sodium) should be avoided as far as possible during pregnancy. This is because of neural tube defects caused in offspring during pregnancy. The above statement is very important during the first trimester of pregnancy. I would also like to inform you that Olanzapine is largely safe during pregnancy and there is no data supporting any adverse effect of Olanzapine during pregnancy. Considering the above facts, I feel increasing the dose of Olanzapine and stopping of Dicorate is the possible strategy for your sister.

Since the increase or decrease in dose depends on multiple factors (body weight, previous episodes, response to medications, the severity of episodes, number of episodes, family history), it is not possible for anyone (including me) to speculate effective dose for an individual patient without examining all relevant factors. I request you to see her psychiatrist along with your sister for a final opinion.

For more information consult a psychiatrist online --> https://www.icliniq.com/ask-a-doctor-online/psychiatrist

Was this answer helpful?


Related Questions:
Taking medicines for bipolar disorder, but unable to sleep. Is there any suggestions?

When i go to the toilet i pass my stool and then when i wipe there is blood on the tissue   Read full

No medicines seem to work for my anxiety. Can you suggest any solution?

When i go to the toilet i pass my stool and then when i wipe there is blood on the tissue   Read full

What is the treatment for delusion of jealousy?

When i go to the toilet i pass my stool and then when i wipe there is blood on the tissue   Read full


This is a sponsored Ad. icliniq or icliniq doctors do not endorse the content in the Ad.

Also Read Answers From:

Comprehensive Medical Second Opinion.Submit your Case

Also Read

Herd Immunity
Herd immunity is nothing but an indirect protection from an infectious disease that can work only for a few diseases. To...  Read more»
Why Do Some COVID-19 Patients Test Negative?
COVID-19 has resulted in a pandemic and has caused serious health crises worldwide. When we develop the symptoms of COV...  Read more»
Post-Traumatic Stress Disorder (PTSD): Reliving the Trauma
PTSD is a mental health condition where the person who undergoes an extremely stressful condition, develops disturbing t...  Read more»

Ask your health query to a doctor online?

Ask a Psychiatrist Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website.