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What is the accuracy of HIV CMIA on 26th day post exposure?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

I have taken an HIV (human immunodeficiency virus) CMIA (chemiluminescent microparticle immunoassay) test on the 26th day after a sexual encounter. The result came back negative. After that, I had protected sex. But I saw some blood on the inner parts of my partner.

At that time, I had two pimples on my penis at the end. I am concerned about it. Is this HIV test taken on the 26th day conclusive?

Kindly help.

Thank you.

Hi,

Welcome to icliniq.com.

HIV (human immunodeficiency virus) test taken on the 26th day of post-exposure is quite assuring, but a confirmatory HIV antibody test is required to be taken at three months after the last exposure.

You do not have any specific symptoms to diagnose HIV. Your present symptoms can occur due to various reasons, and it does not mean HIV. Do some tests for diagnosing sexually transmitted infections such as HBsAg (hepatitis B virus antigen), anti-HCV (hepatitis C virus), VDRL (venereal disease research laboratory), gonorrhea, herpes simplex 1 and 2.

Try to do tests to know your vitamin D3 and vitamin B12 levels. Revert with your reports.

I hope this information provides some clarity and reassurance.

Please feel free to reach out if you have any further questions.

Thank you.

Patient's Query

Hi doctor,

Thank you for your reply.

Since the day of exposure, I have been monitoring my temperature daily. This morning, it was 35.8 °C; in the afternoon, 36.4 °C; and in the evening, 36.8 °C.

Kindly help.

Thank you.

Hi,

Welcome back to icliniq.com.

It is good to know that you do not have a fever. It assures you of having a negative HIV result taken at 26 days. A confirmatory test should be taken at three months. Revert with the remaining STI reports.

I hope this information provides some clarity and reassurance.

Please feel free to reach out if you have any further questions.

Thank you.

Patient's Query

Hi doctor,

Thank you for your answer.

I have done all the tests, and I will get my results soon. I am attaching some reports now.

Kindly help.

Thank you.

Hi,

Welcome back to icliniq.com.

I am not able to open your attached reports.

Thank you.

Patient's Query

Hi doctor,

Kindly go through my attachment.

Kindly help.

Thank you.

Hi,

Welcome back to icliniq.com.

It is not clear. (Attachment removed to protect the patient's identity).

Thank you.

Patient's Query

Hi doctor,

I am attaching it again. Kindly go through it.

Please help.

Thank you.

Hi,

Welcome back to icliniq.com.

I am not able to see your reports.

Thank you.

Patient's Query

Hi doctor,

I have done tests to know my values of vitamin B12 and vitamin D3. I have done tests for syphilis, HIV, herpes 1, and herpes 2.

Kindly help.

Thank you.

Hi,

Welcome back to icliniq.com.

I have gone through the reports (attachment removed to protect patient identity). Your vitamin D level is low, and herpes IgG is positive. Please mention whether you have any genital lesions.

Please help.

Thank you.

Patient's Query

Hi doctor,

I am attaching my syphilis report. I do not have any lesions on my penis. But I have some small pimples on it. Will a positive herpes result indicate a serious issue?

Kindly help.

Thank you.

Hi,

Welcome back to icliniq.com.

I am not able to see your reports.

Thank you.

Patient's Query

Hi doctor,

I do not have any lesions on my penis. But I have some small bumps on my genitals. I am waiting to get my complete report. Is there any test that gives a conclusive result for HIV?

Kindly help.

Thank you.

Hi,

Welcome back to icliniq.com.

You seem to have been exposed to the herpes virus in the past. If you have any active genital or oral lesions due to herpes virus, then they have to be treated.

I hope this helps you.

Thank you.

Patient's Query

Hi doctor,

I am attaching my reports. I am attaching the images of bumps present on the genitals.

Kindly help.

Thank you.

Hi,

Welcome back to icliniq.com.

You have low vitamin D levels. Take Cholecalciferol once a month with milk. You have a positive result for IgG herpes. All the other results are negative.

Your picture is not clear. It likely presents with folliculitis. Maintain your hygiene and apply Neomycin ointment locally. To confirm HIV, it is necessary to do tests after three months of exposure to get a conclusive result.

I hope this helps you.

Thank you.

Patient's Query

Hi doctor,

Do I need to do an HIV RNA (Ribonucleic acid) PCR (Polymerase Chain Reaction) test?

Kindly help.

Thank you.

Hi,

Welcome back to icliniq.com.

Even after getting a negative result in RNA PCR, you need to do a confirmatory HIV antibody test after three months.

I hope this helps you.

Thank you.

Patient's Query

Hi doctor,

refer attached confirmatory hiv test after three months. please confirm now the test is conclusive. also since last three days i am having a rash on back . dermatologist said it is herpes zoster. i read herpes zoster is common among hiv positive people. please confirm is herpes zoster intial symptom of hiv.

Kindly help.

Thank you.

Hi,

Welcome back to icliniq.com.

1) Your test report, post three months of exposure is negative. If there is no more exposure, other than you mentioned, no further test is required for HIV.

2) Herpes zoster can occur in any individual even without HIV. It is a viral illness and occurs more in this season. You can send picture of lesion, as I can recommend you treatment. Moreover, for herpes zoster, treatment needs to be initiated and completed earliest possible, so as to prevent post herpes complications.

I hope this information provides some clarity and reassurance.

Please feel free to reach out if you have any further questions.

Thank you.

Patient's Query

Hi doctor,

Since the event I am so much in depression of getting hiv . I have had a very bad 4 months of my life. Hope now I can relax . I have since then did not even looked at any girl. I was so much disturbed. Please refer attached image for rash on back which the dermatologist said is herpes zoster. Please see as he also told herpes zoster is common in hiv positive. Please guide.

Kindly help.

Hi,

Welcome back to icliniq.com.

Your test result for Human Immunodeficiency Virus (HIV) is conclusively negative, provided there has been no further exposure (Attachment removed to protect the patient's identity). The recommendation is to get tested again at three months. If that result is also negative and there has been no additional exposure, no further HIV testing is required.

Herpes zoster can occur in individuals with HIV, but as mentioned earlier, it is also commonly seen in people without HIV. There are multiple reasons why herpes zoster may appear, and one of the main triggers is stress. It can also be associated with fever.

The lesions on your back appear to be suggestive of herpes zoster. You may have already been prescribed an antiviral medication and a pain reliever. You can continue with that, or follow the treatment plan mentioned below:

  • Tablet Valacyclovir 1 gram every eight hours (three times daily) for five days.
  • Tablet Paracetamol 650 milligrams (mg) every eight hours for three days.
  • I suggest you drink plenty of fluids at least 12 to 14 glasses of water daily. The antiviral medication should be taken for the full five-day course. If you experience pain after completing the treatment, please consult for further management.

I hope this information provides some clarity and reassurance.

Please feel free to reach out if you have any further questions.

Thank you.

Medically reviewed byDr. Vinodhini J.

Published At March 17, 2020
Reviewed AtApril 7, 2026

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