HomeAnswersPathologyhiv testingPlease explain to me how the CMIA combo for HIV testing is done.

Please explain about the CMIA test for HIV testing.


The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At March 23, 2019
Reviewed AtSeptember 28, 2023

Patient's Query

Hello doctor,

I shall be thankful to you if you please answer a few of my queries. How CMIA (chemiluminescent magnetic microparticle immunoassay) combo for HIV (human immunodeficiency virus) testing is done? How reliable it is at 175 and 180 post incidence. INDEX was 14 and 08, respectively. What are the chances of error in the result? (Done at two different labs). Even after three years, I have no medical issues. Please give me an awareness of procedure reliability.


Welcome to icliniq.com.

Below are the specific answers for your questions. CMIA (chemiluminescent magnetic microparticle immunoassay)is based on chemiluminescence principle and it is performed on an automated analyzer. It is the most effective technique nowadays to rule out HIV. CMIA can almost 100 % rule out HIV after 90 days of exposure. Usually, in most of the patients, CMIA can be effective after six weeks of exposure. So after 175 days of exposure, you need not to worry about HIV (human immunodeficiency virus). The index value is cut off value based on which the result is given. The chance of error is very less. After testing for two times the chance of error is almost nil. After three years of exposure there is no medical issue, so the chances of HIV is very less.

Patient's Query

Thank you doctor,

Had it checked both antigen and antibodies? Can I go with my life normally?


Welcome back to icliniq.com.

Yes, CMIA detects both antigens as well as antibodies. You can go ahead in life.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Goswami Parth Rajendragiri
Dr. Goswami Parth Rajendragiri


Community Banner Mobile
By subscribing, I agree to iCliniq's Terms & Privacy Policy.

Read answers about:

hiv testingcmia

Ask your health query to a doctor online


*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.

This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy