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I have a family history of polyps. Should I be concerned?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

A polypoid mucosa with budded, branched, and crowded hyperchromatic cells that replace normal goblet cells, with increased cell turnover noted. What does this mean?

Please help. Thank you.

Hi,

Welcome to icliniq.com.

You have not provided the history of your illness, apart from the fact that this report is also a part of a full report. Yet a generalized report of this type points to dysplasia. If you need precise information, please share your detailed history and upload the scanned reports.

I hope this helps you.

Thank you.

Patient's Query

Hi doctor,

Thank you for your reply,

I have a family history of colon cancer and colon polyps. I have bouts of diarrhea and hematochezia. Colonoscopy was performed, and hot forceps were used to completely excise a sessile polyp 6 mm by 5 mm in the mid-transverse colon. The final pathologic diagnosis was tubular adenoma.

But, I am confused with that diagnosis due to the microscopic description that states polypoid colonic mucosa with irregularly budded and branched glands containing crowded hyperchromatic cells that replace normal goblet cells. Increased cell turnover was noted. It also says no high-grade dysplasia is seen. But everything I read points to dysplasia. I am perplexed, and the doctor has not reached out to me for any follow-up plan.

Should I be concerned or follow up in ten years? I am 51 years old, and at the age of 37, I had polyps removed, showing distant sawtooth-like glandular transformation at the surface of polyps with appearing tubular glands at the base, one of which was in the rectum. I am probably worrying for nothing and will follow up in ten years. I just wanted a second set of eyes to review the diagnosis.

Thank you.

Hi.

Welcome back to icliniq.com.

Thanks for your follow-up.

Considering that you have a family history of colon cancer, I would suggest a frequent follow-up through clinical if you have any repeated symptoms. With the report mentioning no high-grade dysplasia, it is a favorable report. But do keep a watch on your GI (gastrointestinal) symptoms, as sessile polyps are more prone to malignancy.

I hope this clears all your doubts. Do not panic, but all the more, do not be careless of any symptoms.

I wish you a healthy life ahead.

Thank you.

Medically reviewed byDr. Preetha. J

Published At October 2, 2020
Reviewed AtSeptember 30, 2025

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