HomeAnswersObstetrics and Gynecologydouble marker test

Does the double marker test show a risk of Down's syndrome?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

This is the report of double marker test of my wife:

Corrected MoM and calculated risks:

  1. fb-hCG 165 ng/ml 3.82 Corr. MoM
  2. PAPP-A 1.84 mlU/ml o.45 Corr. MoM

Ultrasound data:

  1. Nuchal translucency 1.00 mm
  2. CRL 60 mm 0.64 MoM
  3. Gestational age by CRL 12+ 2 Nasal bone present
  4. Gestational age on the day of serum taking 12+ 2

Risk at term:

  1. Biochem. risk +NT 1:356 (below cut off).
  2. Double test >1:50 (above cut off).
  3. Age risk 1:1515.
  4. Trisomy 13/18 +NT.
Answered by Dr. Sravanthi Nuthalapati

Education:

MBBS

Professional Bio:

Dr. Sravanthi Nuthalapati is a skilled and compassionate Obstetrician and Gynecologist. Her expertise includes high-risk pregnancy management, infertility evaluation, menstrual disorder treatment, PCOS management, and comprehensive prenatal and postnatal care. She is also well-versed in minimally invasive gynecological procedures and is committed to providing personalized and evidence-based care for women’s health at every stage of life.

This doctor is not available for online consultations on the platform anymore.

Hello,

Welcome to icliniq.com.

To explain you the report in plain language, first of all, let me tell you that the dual marker test is just a screening test for Down's syndrome and other chromosomal anomalies like trisomy 13/18. So, the test involves calculation of the risk of carrying a Down's syndrome baby by the mother, which is then compared with the general population's risk. In your case, although the risk based on serum markers is high, the combined risk taking into account the age, NT, and the markers is still below the cut-off. So, it means it is a low risk.

Medically reviewed by iCliniq medical review team
Published At January 16, 2018
Reviewed At May 22, 2024

Education:

MBBS

Professional Bio:

Dr. Sravanthi Nuthalapati is a skilled and compassionate Obstetrician and Gynecologist. Her expertise includes high-risk pregnancy management, infertility evaluation, menstrual disorder treatment, PCOS management, and comprehensive prenatal and postnatal care. She is also well-versed in minimally invasive gynecological procedures and is committed to providing personalized and evidence-based care for women’s health at every stage of life.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Education:

MBBS

Professional Bio:

Dr. Sravanthi Nuthalapati is a skilled and compassionate Obstetrician and Gynecologist. Her expertise includes high-risk pregnancy management, infertility evaluation, menstrual disorder treatment, PCOS management, and comprehensive prenatal and postnatal care. She is also well-versed in minimally invasive gynecological procedures and is committed to providing personalized and evidence-based care for women’s health at every stage of life.

This doctor is not available for online consultations on the platform anymore.

Listen to related tracks in our music library
Comprehensive Second Opinion

Ask your health query to a doctor online

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.