HomeAnswersObstetrics and Gynecologydouble marker testShould I be worried about my second-trimester anomaly scan, which is positive for two markers?

My second anomaly scan shows two markers for DS. Is there a need to worry?

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The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Answered by

Dr. Deepti Verma

Medically reviewed by

iCliniq medical review team

Published At September 29, 2017
Reviewed AtFebruary 1, 2024

Patient's Query

Hello doctor,

I am a 31 year old female. My first trimester NT and double marker test showed a very low risk of 1:3690 for DS and 1:100000 for two other abnormalities. During the second-trimester anomaly scan, the doctor found two markers, CP cyst and mild RPD 4 mm and 4.5 mm. I have given blood for NIPT but did not get any results. I am at 23 weeks now and stressing out and getting really depressed. I have no family history of abnormalities. Is there a need to worry?

Answered by Dr. Deepti Verma

Hello,

Welcome to icliniq.com.

I have gone through your question and understand the concerns. The risk in serum screening is low. Choroid plexus cyst usually resolves by 26 weeks, if present as a normal variant. A renal pelvis more than 7 mm is abnormal, but more than 4 mm is doubtful. Hence, There is no reason to panic as even after modifying the risk, the chances of chromosomal anomalies are very low. NIPT (non-invasive prenatal testing) is most likely to be negative.

Hope you found the answer helpful.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Deepti Verma
Dr. Deepti Verma

Fetal Medicine

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