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Which birth control is safe with Levonorgestrel allergy?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am a 20-year-old female, weigh 140 pounds, and am 5.6 feet tall. I am allergic to Levonorgestrel and want to take an emergency contraceptive pill. What will happen if I do?

I previously developed a rash after using pure progesterone cream.

Please help.

Thank you.

Hello,

Welcome to icliniq.com.

It is always difficult to predict which drug might cause an allergy and when. Since you have previously had an allergic reaction to pure progesterone cream, it is challenging to determine if you might react to an emergency contraceptive pill. However, creams often contain multiple ingredients in addition to the active drug, which could have contributed to your reaction.

Additionally, I would like to understand the reason for taking the pill. Is it for emergency contraception, or is your gynecologist recommending it for another reason? Knowing this will help us plan appropriately.

If you do need to take it, we can consider using anti-allergic medication to reduce the risk. I recommend taking an antihistamine like Fexofenadine an hour before taking the pill. Still, be vigilant and monitor yourself for any signs of a reaction. Consult your specialist doctor, discuss with him or her, and start taking the medicine after their consent.

Do let me know the main indication, and I can guide you accordingly.

Thank you.

Patient's Query

Hello doctor,

Thank you for your suggestions.

I want to use it as an emergency contraceptive.

Kindly suggest.

Hello,

Welcome back to icliniq.com.

If you need it for emergency contraception, it seems unavoidable. The best approach is to take an antihistamine before using the medication. Although hormonal medications typically do not cause significant reactions, given your history of allergies, we should exercise caution.

Make sure to take it in the presence of someone who can help you get to the ER (emergency room) if needed. While the chances of a severe reaction are low, it is best to be prepared.

Please let me know if you experience any problems.

Thank you.

Medically reviewed byiCliniq medical review team

Published At May 30, 2017
Reviewed AtNovember 12, 2025

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