How to take Plan B if you are allergic to Levonorgestrel?

Q. I am allergic to Levonorgestrel. How do I take Plan B?

Answered by
Dr. Naval Mendiratta
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on May 30, 2017 and last reviewed on: May 19, 2023

Hello doctor,

I am a 20 year old female, who weighs 140 lbs and 5.6 feet tall. I am allergic to Levonorgestrel, and I want to take Plan B. What will happen if I do take it? I developed a rash in high school after using pure Progesterone cream.



Welcome to

  • Well, with drugs it is always hard to say which one will cause allergy and when. One can never predict.
  • Since you already had an allergic reaction to pure Progesterone cream, it is a tough call. But the creams usually have a lot of ingredients apart from the drug to keep them in their formed state. So, there is a chance one of them may have caused the reaction.
  • Secondly, I would like to know the reason for taking the pill. Is it for emergency contraception or your gynecologist wants to put you on it? As we will have more time to act on it.
  • But yes, if you do have to take it, we can always take a chance by giving it to you with anti-allergics. I suggest taking an anti-allergic like Allegra (Fexofenadine) an hour before taking the pill. But still, be on your toes to watch out for a reaction. Consult your specialist doctor, discuss with him or her, and start taking the medicine after their consent.

Do let me know the main indication, and I can guide you accordingly.

Hi doctor,

Thank you for your suggestions. I want to use Plan B as an emergency contraceptive.



Welcome back to

  • Well, if it has to be an emergency contraception, then we cannot avoid it, so the best way out is you take an anti-allergic prior to the medicine. Although, hormonal medicines do not cause much of a reaction, but considering you have had allergy to it in the past, we will be more cautious.
  • Just make sure you take it in someone's presence, so just incase a reaction happens, you can be taken to the ER. Although chances are less but best we take it with precautions.

Do let me know if any problem happens.

For more information consult an allergy specialist online -->

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