Dr. Muhammad Zohaib Siddiq
Cardiology
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Patient's Query
Hello doctor,
I am a heart patient. I had two open-heart surgery for my valve replacement. I have a mechanical valve, and I need to take anticoagulants daily. At present I am on Acitrom 2 mg. I need to ask whether I can become pregnant after all these complications. Is it possible to become a mother for me or not. What are its complications?
Hello,
Welcome to icliniq.com.
Acitrom (Nicoumalone) is not safe in pregnancy. You may have to switch to low molecular weight Heparin subcutaneous injection twice daily. Anti-Xa levels must be checked after four to six hours of injection, and the target anti-Xa levels are 0.8 - 1.2 U/mL. The drug of choice for mechanical valves is Warfarin. If INR (international normalized ratio) remains in the target range of less than 5 mg of Warfarin, it can be continued throughout pregnancy. However, if a dose is more than 5 mg, it should be switched to low molecular weight Heparin during the first trimester and Warfarin in the second and third trimester. In patients who want to be pregnant, a bioprosthetic valve is implanted.
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Cardiology
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