Is pregnancy possible while taking Nicoumalone?
Patient's Query
Hello doctor,
I am a heart patient. I had two open-heart surgery for my valve replacement. I have a mechanical valve, and I need to take anticoagulants daily. At present I am on Nicoumalone 2 mg. I need to ask whether I can become pregnant after all these complications. Is it possible for me to become a mother? What are its complications? Please help.
Thank you.
Hello,
Welcome to icliniq.com.
Nicoumalone is not safe in pregnancy. You may have to switch to low molecular weight Heparin subcutaneous injection twice daily. Anti-Xa levels must be checked after four to six hours of injection, and the target anti-Xa levels are 0.8 - 1.2 U/mL. The drug of choice for mechanical valves is Warfarin.
Suppose INR (international normalized ratio) remains in the target range of less than 5 mg of Warfarin. In that case, it can be continued throughout pregnancy. However, suppose a dose is more than 5 mg. In that case, it should be switched to low molecular weight Heparin during the first trimester and Warfarin in the second and third trimesters. In patients who want to be pregnant, a bioprosthetic valve is implanted.
I hope this helps.
Please revert so I can assist you further.
Thank you.
Same symptoms don't mean you have the same problem. Consult a doctor now!
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