Why is my daughter suffering from GAD become resistant to Celexa?

Q. Celexa is not working now for my 12 year old girl with GAD. Why?

Answered by
Dr. K. V. Anand
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Oct 21, 2017 and last reviewed on: Jun 26, 2023

Hi doctor,

My 12-year-old girl has been on Celexa from the age of seven years for GAD. She has been on 20 mg for the past three years. It has worked well for anxiety and mood regulation. She has been irritable and angry with some depression for the past six months. Would you think we should look at changing the medications? Should we go for an add-on medication or increase the dosage of the current one? She is also taking Synthroid, Singulair, and Benadryl.



Welcome to icliniq.com.

Generalized anxiety disorder is a simple anxiety disorder that is very easy to treat with medicines if it is combined with psychotherapy and progressive counseling. Medicines alone cannot cure it. Celexa (Citalopram) used to help her with anxiety and mood swings is not working because she is 12 years now. There are many aspects to be looked into including the puberty onset and psychological changes that take place during the onset of adolescence. Attention deficit hyperactivity disorder (ADHD) also should be suspected. I suggest not worrying much and consulting your psychiatrist. The change of medicine is not needed for GAD (generalized anxiety disorder) but, should be assessed for ADHD or stress disorder. I also suggest regular cognitive behavior therapy and progressive counseling through online mediums.

Thank you.

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