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A lot of individuals have a generalized anxiety disorder, and this often causes significant comorbidity and depression. What kind of physical defect do you have? Regarding masturbation, it is a safe and healthy habit. It does not affect physical, mental, or reproductive health. So, do not worry. Do take treatment for generalized anxiety and depression. SSRI (selective serotonin reuptake inhibitor) drugs like Fluoxetine or Escitalopram can be used for treatment. Both are activating and will not cause sleepiness or drowsiness. These drugs are non-addictive and safe to use. For episodes of severe anxiety, Propranolol can be used. So please consult a psychiatrist for evaluation and treatment. With regular treatment in optimum doses, you will be alright. Take care.