Q. Is it possible to have Sjogren's syndrome if lab reports show positive anti-SSA, anti-SSB, and rheumatoid factors?

Hello doctor,

I recently had a complete lab test with my primary care provider in which my alanine transaminase (ALT) was 60 units per liter. My gamma globulin returned at 3.3 g/dL, and Sjogren's anti-SSA and anti-SSB levels were more than eight units per mL. The rheumatoid factor level was 34.2 IU per mL, and the vitamin D level was 24.4 ng per mL. Everything else was within normal range, but I was told I was suffering from hepatitis C, although my hepatitis test returned negative. Is this correct? The lab test that I completed include a hepatitis panel test, comprehensive metabolic panel (CMP) test, serum and plasma test, screening of antinuclear antibodies (ANA), vitamin D test, and C-reactive protein test.

Thank you doctor for the reply,

I have had terrible back pain for over seven years, especially while sitting or standing in one position. Recently, it has been to the point where I am unable to get up from the bed or toilet. Additionally, my knees often hurt while standing, and I have body soreness when I wake up in the morning. However, I do not have any obvious swelling. I also experience pain in my heels and wrists, and I randomly get shock sensations in my wrists. I experience dryness of mouth and tongue irritation, especially with acidic foods. I also have a rash on my tongue that is typically red with a white border. My eyes are often dry, but I wear contact lenses which sometimes makes it worse. I do not experience abdominal pain, nausea, or vomiting, but I usually have diarrhea and bladder issues. Sometimes, I feel a strong urge to urinate, but when I go to the toilet, I have difficulty passing urine.