High Ferritin

Ferritin is an iron-containing protein stored inside the cells. Ferritin levels help determine iron deficiency and iron overload. High ferritin levels indicate iron overload or high iron levels in case of hemochromatosis, repeated blood transfusions, and accidental surplus iron supplement ingestion. High iron levels are dangerous as they may build up in various organs and damage them over time. High ferritin levels may be present even if the body's iron level is normal, as in acute infections, COVID-19 (coronavirus disease 2019), alcoholism, hepatitis, etc.

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What is the suggested food for a baby with thalassemia major?

Query: Hello doctor, My baby girl is 3.5 years old. She has thalassemia major and her ferritin level is 3000 ng/ml. What food is good for her?  Read Full »

Dr. Prakash H. Muddegowda

Answer: Hello, Welcome to icliniq.com. Based on your query, my opinion is as follows: Iron intake should be reduced. Vegetarian diet will be better as iron content is low. The diet that can be followed include: 1. Importantly avoid vitamin C or citrus food up to four hours after food as it helps in impr...  Read Full »

What are the causes of sudden increase in ferritin level in my 34-year-old wife?

Query: Hi doctor,My wife is 34 years old and has increased ferritin level after two iron infusions. She has a low CRP, with no evidence of overload in heart and liver, cancers, or hemochromatosis. Two hematologists said that they did not anticipate a problem. She took blood CRP sediment test, MRI, blood t...  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hello,Welcome to icliniq.com.Increased ferritin indicates iron bone marrow storage level. It is natural to have high ferritin temporarily after iron supplement. If she acquires COVID-19 (coronavirus disease), then ferritin level and CRP (C-reactive protein) can go high because it is acute phase reac...  Read Full »

Do I have ferroportin disease if my ferritin level and transferrin saturation are high?

Query: Hello doctor, I am a 29-year-old male, and I fear that I might have ferroportin disease. I persistently have high ferritin levels, and my transferrin saturation is also mildly above the normal range. I have also looked at my genotyping on chromosome 2 and noticed a single nucleotide mutation for m...  Read Full »

Dr. Ajeet Kumar Lohana

Answer: Hello, Welcome to icliniq.com. Having H63D (histidine at amino acid position 63) carrier does not indicate a diagnosis of hemochromatosis. Similarly, you have one of the gene alleles for ferroportin disease. However, the transferrin saturation should be low in ferroportin disease. On the...  Read Full »

Will hemochromatosis cause grayish discoloration of the face?

Query: Hi doctor,I have grayish skin on the face, but my hemoglobin is normal. I have leucocytes at 11.1, ferritin 402, and C-reactive protein 13. I am on Zoloft Risperdal and Remeron. Kindly give your opinion.  Read Full »

Dr. Muhammad Zubayer Alam

Answer: Hi, Welcome to icliniq.com. I can understand your concern. According to your statement, you have been suffering from grayish discoloration of the skin in the face. Again, according to your investment reports, your leucocytes level and CRP (C-reactive protein) level are above normal, and your fe...  Read Full »

What are the laboratory findings in a COVID-19 positive patient?

Query: Hi doctor, Today is my thirteenth day of COVID-19. From yesterday I do not have a fever. I even got tested today and awaiting the results. My oxygen saturation is above 96 percent. I just got my blood report which shows elevated CRP, ferritin, and IL-6 levels, which worries me. I have attached repo...  Read Full »

Dr. Muhammad Zubayer Alam

Answer: Hi, Welcome to icliniq.com. According to your reports (attachments removed to protect the patient's identity), your D-dimer level is normal, so you do not have to worry because patients with raised D-dimer levels are more prone to develop bleeding disorders like DIC (disseminated intravascular coagu...  Read Full »

How to reduce the levels of iron and ferritin?

Query: Hello doctor, I am a 61 year old male. For many years, I was treated for hemochromatosis. Then, about 12 years ago, I had a genetic test. The results prompted the hematologist to abruptly stop the recurring phlebotomies. I do not recall the test result and apparently, it cannot be located. But, I r...  Read Full »

Dr. Desai Santosh Badaku

Answer: Hi, Welcome to icliniq.com. I understand your concern. Your iron saturation and serum ferritin is high and these are suggestive of iron overload or hereditary hemochromatosis (HH). You talked about a test that was done and then the hematologist stopped the phlebotomy. I think, probably he must have ...  Read Full »

Please suggest ways to reduce high iron levels.

Query: Hi doctor, My mother has been transfused with at least 11 to 12 units of blood during a period of two months. This was done on a false diagnosis of iron deficiency anemia. It was a false diagnosis because transferrin receptor was never used to come to this diagnosis. She has had elevated CRP for a ...  Read Full »

Dr. Prakash H. Muddegowda

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows Normally in hemochromatosis (iron deposition disease), serum transferrin, iron and ferritin levels will be usually high. All the symptoms and signs point towards hemochromatosis, possibly due to iron overloading secondary to m...  Read Full »

What should I do to lower my ferritin levels?

Query: Hello doctor, My ferritin levels are very high. It is 571. I am always feeling tired. Can you prescribe some medicines?  Read Full »

Dr. Muhammad Zubayer Alam

Answer: Hi, Welcome to icliniq.com. I can understand your concern. According to your statement, you have recently done serum ferritin and your level is 571.30ng which is very high. Your cholesterol and triglyceride levels are also high. Common causes of high ferritin levels are obesity, fatty liver, infl...  Read Full »

Thalassemia major with factor 13 deficiency and high ferritin levels. Please advise.

Query: Hello doctor, I am thalassemia major with factor XIII decficiency, HCV+. I transfuse platelet or FFp daily and RCC weekly. All these things are reacting in my body. My ferritin level is 15000 after chelation therapy. This also reacts badly every time. I am 28 years old. How much time do I have to l...  Read Full »

Dr. Prakash H. Muddegowda

Answer: Hi, Welcome to icliniq.com. Based on your query, my opinion is as follows: The serum ferritin level of 15000 is definitely too high. Along with HCV, the prognosis is somewhat poor. However, without knowing the amount of iron deposition in tissues like the liver, heart, etc, and also the amount o...  Read Full »

How to reduce my serum ferritin level?

Query: Hi doctor, My ferritin level is 1500, and I want to bring it down to 150. How much will one DFO IV session or each Exjade pill reduce the ferritin level on an average? I am a healthy individual, and I do not have HIV, HCC, or any other disease.  Read Full »

Dr. Goswami Parth Rajendragiri

Answer: Hi, Welcome to icliniq.com. Your serum ferritin is high, so the cause should be found out first. It can be hemochromatosis, in which excess iron is stored in the bone marrow. Deferoxamine is used for increased iron storage in thalassemia patient. For high ferritin, phlebotomy is also another mode o...  Read Full »

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