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How to go ahead with hormone replacement therapy?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I take Clorazepate, Quetiapine, Akineton (Biperiden), Ludiomil (Maprotiline) and Lyrica (Pregabalin). I am wondering whether I can go ahead with hormone replacement therapy which includes Estrogen and Spironolactone.

Answered by Dr. Divakara P

Education:

MBBS

Professional Bio:

Dr. Divakara. P is a Diabetologist and an Endocrinologist specializing in Pain Medicine and Pulmonology with 18 years of clinical experience. He completed his MBBS at the Karnataka Institute of Medical Sciences in 2006 and MD in General Medicine at the Rajiv Gandhi University of Health Sciences in 2011. He is qualified to diagnose and treat disorders of the endocrine glands. Currently, he is practicing in Dr. Divakara's Speciality Clinic, Bangalore, Karnataka, India.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

I would like to know first for what purpose you are on these medicines? What is your purpose of planning to go for hormone replacement?

Patient's Query

Hello doctor,

I am a male to female transsexual.

Answered by Dr. Divakara P

Education:

MBBS

Professional Bio:

Dr. Divakara. P is a Diabetologist and an Endocrinologist specializing in Pain Medicine and Pulmonology with 18 years of clinical experience. He completed his MBBS at the Karnataka Institute of Medical Sciences in 2006 and MD in General Medicine at the Rajiv Gandhi University of Health Sciences in 2011. He is qualified to diagnose and treat disorders of the endocrine glands. Currently, he is practicing in Dr. Divakara's Speciality Clinic, Bangalore, Karnataka, India.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome back to icliniq.com.

I still need more information.

Akineton (Biperiden) is a drug used in a neurological disease called Parkinson's disease and Maprotiline is an antidepressant drug. You have not mentioned why you are on these drugs. As of safety, the above mentioned medicines with HRT (hormone replacement therapy) is concerned, it can be taken together. There are no such significant interactions between these medications at your age. In fourth or fifth decade of life some heart problems may arise. If regular testing is done, then that can be avoided. But, I presume you have go through the risk of taking HRT as HRT by themselves comes with lot of side effects.

Patient's Query

Hello doctor,

I apologize for not being enough descriptive. I take Akineton because I had a severe anxiety attack which led to muscle spasm and loss of control of my facial muscles. I also had trouble breathing during the attack. It has been well over two months since my attack and I have had no spasm or loss of muscle control (with the medication) and I am breathing fine now. So, I feel I am completely healed now. I have no idea whether the spasm and loss of muscle control will come back if I stop taking the Akineton. As for the other drugs I am taking for depression and for calming down my nerves and anxiety. Should I be fine with starting the hormone replacement therapy?

Thank you for taking the time to answer.

Answered by Dr. Divakara P

Education:

MBBS

Professional Bio:

Dr. Divakara. P is a Diabetologist and an Endocrinologist specializing in Pain Medicine and Pulmonology with 18 years of clinical experience. He completed his MBBS at the Karnataka Institute of Medical Sciences in 2006 and MD in General Medicine at the Rajiv Gandhi University of Health Sciences in 2011. He is qualified to diagnose and treat disorders of the endocrine glands. Currently, he is practicing in Dr. Divakara's Speciality Clinic, Bangalore, Karnataka, India.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome back to icliniq.com.

Yes, you can go ahead with hormone replacement therapy (HRT) since your muscle spasms have stopped now. Akineton can be first reduced in dosage and eventually stopped. Kindly discuss this with your treating doctor.

Answered by Dr. Divakara P
Medically reviewed by iCliniq medical review team
Published At April 15, 2016
Reviewed At May 29, 2023

Education:

MBBS

Professional Bio:

Dr. Divakara. P is a Diabetologist and an Endocrinologist specializing in Pain Medicine and Pulmonology with 18 years of clinical experience. He completed his MBBS at the Karnataka Institute of Medical Sciences in 2006 and MD in General Medicine at the Rajiv Gandhi University of Health Sciences in 2011. He is qualified to diagnose and treat disorders of the endocrine glands. Currently, he is practicing in Dr. Divakara's Speciality Clinic, Bangalore, Karnataka, India.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

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Decision Helper
Hormone Replacement Therapy for Transsexuals Decision Helper

Is Hormone Replacement Therapy right for you?

This tool helps male-to-female transsexuals assess their readiness for hormone replacement therapy (HRT) and identify key discussion points with a doctor.

This tool provides educational information only and does not diagnose, treat, or replace professional medical advice. Consult a qualified healthcare professional for personalized medical guidance.

Education:

MBBS

Professional Bio:

Dr. Divakara. P is a Diabetologist and an Endocrinologist specializing in Pain Medicine and Pulmonology with 18 years of clinical experience. He completed his MBBS at the Karnataka Institute of Medical Sciences in 2006 and MD in General Medicine at the Rajiv Gandhi University of Health Sciences in 2011. He is qualified to diagnose and treat disorders of the endocrine glands. Currently, he is practicing in Dr. Divakara's Speciality Clinic, Bangalore, Karnataka, India.

This doctor is not available for online consultations on the platform anymore.

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