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I still need more information.
Akineton (Biperiden) is a drug used in a neurological disease called Parkinson's disease and Maprotiline is an antidepressant drug. You have not mentioned why you are on these drugs.
As of safety, the above mentioned medicines with HRT (hormone replacement therapy) is concerned, it can be taken together. There are no such significant interactions between these medications at your age.
- In fourth or fifth decade of life some heart problems may arise. If regular testing is done, then that can be avoided.
- But, I presume you have go through the risk of taking HRT as HRT by themselves comes with lot of side effects.
Revert back with the details to an endocrinologist online --> https://www.icliniq.com/ask-a-doctor-online/endocrinologist