HomeAnswersGeneral MedicinemalariaShould I take a malaria vaccine before traveling to a malaria-endemic zone?

What are the precautions to be taken before traveling to a malaria-endemic zone?


The following is an actual conversation between an iCliniq user and a doctor that has been reviewed and published as a Premium Q&A.

Medically reviewed by

iCliniq medical review team

Published At February 26, 2024
Reviewed AtMarch 14, 2024

Patient's Query

Hello doctor,

I am a 30-year-old male planning a trip to a malaria-endemic zone, and I am interested in learning more about the malaria vaccine. Can you provide information on the availability, effectiveness, and recommended dosage for the malaria vaccine? Additionally, are there any specific precautions or considerations I should be aware of before getting vaccinated, and how soon before the trip should I receive the vaccine for optimal protection? Please suggest.

Thank you.


Welcome to icliniq.com.

I read your query and can understand your concern.

Two malaria vaccines have been recommended for broader use by the World Health Organization (WHO) and the Centers for Disease Control and Prevention (CDC):

  1. RTS, S/AS01 (RTS, S): This vaccine was the first malaria vaccine to be recommended for broader use in children aged 6 months to 17 months living in regions with moderate to high malaria transmission. The RTS, S vaccine is given in a series of 4 doses, with the first dose given at least six months of age and the subsequent doses given at monthly intervals. The vaccine is partially effective at preventing malaria, with an overall efficacy of about 30 to 40 %. However, it is particularly effective at preventing severe malaria and death from malaria.
  2. R21/Matrix-M: This vaccine is a newer vaccine that is currently being evaluated for wider use. It is more effective than RTS, S, with an overall efficacy of about 70 %. However, it is still under development and is not yet available for routine use.

The RTS, S vaccine is generally safe and well-tolerated. The most common side effects are pain, redness, and swelling at the injection site, as well as fever, headache, and fatigue. These side effects are usually mild and go away on their own within a few days. The CDC recommends that all travelers to areas with malaria take antimalarial medication to prevent infection. However, the RTS, S vaccine can be used in combination with antimalarial medication to provide additional protection.

I hope this helps you.

Thank you.

Same symptoms don't mean you have the same problem. Consult a doctor now!

Dr. Muhammad Zohaib Siddiq
Dr. Muhammad Zohaib Siddiq


Community Banner Mobile
By subscribing, I agree to iCliniq's Terms & Privacy Policy.

Read answers about:


Ask your health query to a doctor online

General Medicine

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.

This website uses cookies to ensure you get the best experience on our website. iCliniq privacy policy