HomeAnswersObstetrics and Gynecologynegative blood group

Could my negative blood group cause any pregnancy complication?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am 3 months pregnant. My blood group is O negative. Will I face any complication during pregnancy due to my negative blood group? I consulted with my doctor, and she told me to take Fertigyn 5000 injection once a week for four weeks. Is it safe? Will it make me get a normal delivery or C-section?

Please help.

Answered by Dr. Aishwarya Parthasarathy

Education:

MD

Professional Bio:

Dr. Aishwarya Parthasarathy is a compassionate and highly trained Obstetrician and Gynecologist specializing in women’s health across all stages of life. She is committed to providing personalized care, supporting pregnancy, managing reproductive health, and addressing gynecological concerns with empathy and expertise. She provides comprehensive antenatal and postnatal care to ensure safe pregnancies and healthy deliveries.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

When there is a negative blood group, there will be attacking agents for the positive blood group in your blood called antibodies. In case your partner is positive, then there are chances of your baby being positive. The first child usually escapes, and in the case of the second child, if positive, the blood might be attacked by the antibodies, and it might cause anemia in the baby. To prevent that, there are anti-D injections given during the first pregnancy itself. Kindly discuss with your obstetrician about anti-D injection. Injection of Fertigyn (human chorionic gonadotropin hCG injection) does not prevent that attack. It is simply to hold your baby inside the uterus. Your obstetrician might have prescribed it for some other reason.

I hope this helps.

Medically reviewed by Dr. K. Shobana
Published At March 5, 2017
Reviewed At December 3, 2025

Education:

MD

Professional Bio:

Dr. Aishwarya Parthasarathy is a compassionate and highly trained Obstetrician and Gynecologist specializing in women’s health across all stages of life. She is committed to providing personalized care, supporting pregnancy, managing reproductive health, and addressing gynecological concerns with empathy and expertise. She provides comprehensive antenatal and postnatal care to ensure safe pregnancies and healthy deliveries.

This doctor is not available for online consultations on the platform anymore.

Education:

BDS

Professional Bio:

Dr. K. Shobana is a Dental Surgeon specializing in oral health and dental care. She is skilled in preventive dentistry and provides oral hygiene education. She can do restorative treatments such as fillings and crowns. She can handle periodontal problems such as gum diseases and periodontitis. She can do root canal treatment.

This doctor is not available for online consultations on the platform anymore.

Same symptoms don't mean you have the same problem. Consult a doctor now!

1,636Visits prepared today
4.8/5User rating
~60 secAverage completion time
Companion

Negative Blood Group Pregnancy Companion

How it works

If you have a negative blood group and are pregnant, understanding Rh incompatibility is important. Here's what you need to know.

1

Rh
Incompatibility

2

Antibodies
Form

3

Pregnancy
Risks

4

Anti-D
Injection

5

Fertigyn
Purpose

6

Delivery
Method

This information is based on general medical guidance. It is not a substitute for professional medical advice; consult a qualified clinician.

Always consult a doctor before taking medication; self-medication carries serious health risks. Take exact prescribed doses, and never start, change, or stop treatment without medical supervision.

Education:

MD

Professional Bio:

Dr. Aishwarya Parthasarathy is a compassionate and highly trained Obstetrician and Gynecologist specializing in women’s health across all stages of life. She is committed to providing personalized care, supporting pregnancy, managing reproductive health, and addressing gynecological concerns with empathy and expertise. She provides comprehensive antenatal and postnatal care to ensure safe pregnancies and healthy deliveries.

This doctor is not available for online consultations on the platform anymore.

Listen to related tracks in our music library
Comprehensive Second Opinion

Ask your health query to a doctor online

*guaranteed answer within 4 hours

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.