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Could my negative blood group cause any pregnancy complication?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hello doctor,

I am 3 months pregnant. My blood group is O negative. Will I face any complication during pregnancy due to my negative blood group? I consulted with my doctor, and she told me to take Fertigyn 5000 injection once a week for four weeks. Is it safe? Will it make me get a normal delivery or C-section?

Please help.

Hi,

Welcome to icliniq.com.

When there is a negative blood group, there will be attacking agents for the positive blood group in your blood called antibodies. In case your partner is positive, then there are chances of your baby being positive. The first child usually escapes, and in the case of the second child, if positive, the blood might be attacked by the antibodies, and it might cause anemia in the baby. To prevent that, there are anti-D injections given during the first pregnancy itself. Kindly discuss with your obstetrician about anti-D injection. Injection of Fertigyn (human chorionic gonadotropin hCG injection) does not prevent that attack. It is simply to hold your baby inside the uterus. Your obstetrician might have prescribed it for some other reason.

I hope this helps.

Medically reviewed byDr. K. Shobana

Published At March 5, 2017
Reviewed AtDecember 3, 2025

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