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What can be the reason for IUFD?

This Premium Q&A, reviewed and published, features a real conversation between an iCliniq user and a physician.

Patient's Query

Hi doctor,

This is about my wife, who had unfortunate IUFD, cardiomyopathy and DIC. She had an absolute normal pregnancy till 9th month. She had no BP, diabetes or other issues throughout and even today. Only issue, she has is migraine and for which she takes Diclogesic. So, it happened on a day of routine checkup when Doppler scan released little less fluid (7.3) around baby and placental calcification that doctor advised C-section. She was empty stomach after breakfast from morning till evening and developed a migraine, which is normal as she had this condition before as well. Gradually, she became breathless, tachycardia and her pulse rate shoot up to 170 or 180 while saturation was around 99 %.

While doctors were trying to stabilize her, they could not track the baby's heartbeat and then she had other above specified conditions. So, I am looking back what could have gone wrong. Below are the few things that I need your help in understanding. We have a son already who is O negative and my wife is A negative. Anti-D was given only in the 28th week of pregnancy and not after CS delivery, which is fine I guess. But, she was not given an Anti-D this time, but stillbirth (boy) was O positive. Hence, wondering if this was one factor if not for IUFD (as all scans till 9th month were normal) at least for DIC afterward? Secondly, to stabilize her migraine when she was posted for C-section she was given Dynapar 75 mg, which looks like another factor that could have caused ductus arteriosus to close before time and IUFD. Please clarify.

Answered by Dr. Anindya Das

Education:

MBBS

Professional Bio:

Dr. Anindya Das is a well-experienced Obstetrics and Gynecologist with 19 years of clinical experience. He completed his MBBS from The West Bengal University in 2005. He then completed his MS in Obstetrics and Gynecology from the University of Calcutta in 2010. He treats his patients with love and care. He is currently working in Kolkata, West Bengal.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome to icliniq.com.

First of all I feel really sorry knowing what happened to you.

It was fine that anti-D was not given after your first child as his blood group is negative. This time around anti-D should have been given. But, that does not explain DIC (disseminated intravascular coagulation). Dynaper is Diclofenac. Maternal administration of Diclofenac usually does not cause premature closure of PDA (patent ductus arteriosus). The IUFD - intrauterine fetal death rather can be explained by less fluid detected by ultrasonography. Though nothing can be said definitely without examining the patient in real time. IUFD itself can explain DIC.

Patient's Query

Thank you doctor,

Do you think Anti-D not being given can probably cause DIC? Because after IUFD, mother and baby blood contact happens and in this case little blood clot was also found after placenta biopsy. Secondly, after the baby was out, discharge summary points out adequate fluid. So, I do not really think that to be the cause of IUFD. In the last scan, the amount of fluid was 7.3 and the baby was 7 lbs. About Diclofenac, as I could read various studies on the internet, it is generally not advised and even if it is given it should be in accordance with mother weight. In our case, 75 mg was given.

Answered by Dr. Anindya Das

Education:

MBBS

Professional Bio:

Dr. Anindya Das is a well-experienced Obstetrics and Gynecologist with 19 years of clinical experience. He completed his MBBS from The West Bengal University in 2005. He then completed his MS in Obstetrics and Gynecology from the University of Calcutta in 2010. He treats his patients with love and care. He is currently working in Kolkata, West Bengal.

This doctor is not available for online consultations on the platform anymore.

Hi,

Welcome back to icliniq.com.

I have mentioned earlier anti-D not being given cannot explain DIC. IUFD can happen due to various reasons. Many things can be said retrospectively, but it is really difficult to comment without examining the patient in real time.

Medically reviewed by iCliniq medical review team
Published At November 11, 2016
Reviewed At October 3, 2023

Education:

MBBS

Professional Bio:

Dr. Anindya Das is a well-experienced Obstetrics and Gynecologist with 19 years of clinical experience. He completed his MBBS from The West Bengal University in 2005. He then completed his MS in Obstetrics and Gynecology from the University of Calcutta in 2010. He treats his patients with love and care. He is currently working in Kolkata, West Bengal.

This doctor is not available for online consultations on the platform anymore.

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Companion

IUFD and DIC Understanding Companion

How it works

Intrauterine fetal death (IUFD) is a deeply distressing event. This section helps you understand some of the medical factors that may be involved.

1

IUFD
Overview

2

Rh
Incompatibility

3

Medication
Concerns

4

Amniotic
Levels

5

DIC
Explained

6

Importance
Assessment

This information is based on general medical guidance. It is not a substitute for professional medical advice; consult a qualified clinician.

Always consult a doctor before taking medication; self-medication carries serious health risks. Take exact prescribed doses, and never start, change, or stop treatment without medical supervision.

Education:

MBBS

Professional Bio:

Dr. Anindya Das is a well-experienced Obstetrics and Gynecologist with 19 years of clinical experience. He completed his MBBS from The West Bengal University in 2005. He then completed his MS in Obstetrics and Gynecology from the University of Calcutta in 2010. He treats his patients with love and care. He is currently working in Kolkata, West Bengal.

This doctor is not available for online consultations on the platform anymore.

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diclofenacdisseminated intravascular coagulation (dic)anti-delta (anti-d) antibodiespatent ductus arteriosus (pda)iufd

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