Q. What can I do to deal with the symptoms of Paroxetine withdrawal?

Answered by
Dr. Parth Nagda
and medically reviewed by Dr. Sneha Kannan
This is a premium question & answer published on May 21, 2020

Hi doctor. I am 21 years old. I was diagnosed 2 years back with obsessive-compulsive disorder. I followed treatment with the help of a psychiatrist who included cognitive behavioral therapy and medication. of medication as many times as I tried to stop paroxetine (seroxat) in collaboration with my psychiatrist of course my body reacted with nausea dizziness and other similar symptoms. So I take a seroxat 20 mg one day and in the next day half alternatevely on my own initiative. This has been going on for the last few months as I was getting one and a half at first and then one. I have been taking them for two years now. I cant stop taking the medicine because I am afraid of the symptoms. What can I do to deal with the symptoms of the drug cut after I have completed the treatment? Thank you in advance for your response.


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Dr. Parth Nagda

# Hello,
thank you for your query.

Paroxetine has a short half life, so that's why , when you are trying to stop it, it is causing you withdrawal symptoms.
There are 2 things you can try.
1. Replacing it with a longer acting SSRI and then stopping it . For example, Start taking Fluoxetine 20mg daily and paroxetine 20mg 1 every alternate day. After 2 weeks, stop paroxetine. After 2 weeks of fluoxtine 20mg ,take for alternate day and stop.
2. Mix the whole 20mg in 200ml glass of juice.
Take 190 ml for 1 day
180 ml the next
170ml the day after and so on and discard the rest.

So that way ,you wont notice the difference.

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