How does Sarilumab work?

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I understand your concern. Sarilumab is a biological medication that is used to treat moderate to severe rheumatoid arthritis (RA) in adults who have not responded well to other treatments. It works by targeting and blocking a specific protein called interleukin-6 (IL-6), which is involved in the inflammatory process that causes joint pain and damage in RA. By inhibiting IL-6, Sarilumab can help reduce inflammation, joint pain, and stiffness in people with RA. It may also help to slow the progression of joint damage and improve overall function and quality of life.

Some potential benefits of Sarilumab for managing intense joint pain in RA include:

Reduced joint pain and stiffness: Sarilumab can help significantly reduce the severity and frequency of joint pain and stiffness, making it easier for your mother-in-law to move around and perform daily activities.

Improved joint function: By reducing inflammation and preventing further joint damage, Sarilumab can help to improve overall joint function and mobility.

Reduced need for other medications: In some cases, Sarilumab may allow your mother-in-law to reduce or discontinue the use of other medications used to manage RA symptoms, such as nonsteroidal anti-inflammatory drugs (NSAIDs) or corticosteroids.

Improved quality of life: By reducing joint pain and stiffness, Sarilumab can help to improve the overall quality of life for people with RA, allowing them to engage in more activities and enjoy a better standard of living.

While Sarilumab can provide significant benefits for managing intense joint pain in RA, there are also some important considerations and lifestyle adjustments that your mother-in-law should be aware of while taking this medication:

Regular monitoring: Your mother-in-law will need to have regular blood tests to monitor her liver function while taking Sarilumab, as liver problems have been reported in some people taking this medication. Her healthcare provider will also need to monitor her for signs of infection or other side effects.

Vaccinations: Your mother-in-law should avoid receiving live vaccines while taking Sarilumab, as this medication may reduce the effectiveness of these vaccines. She should also consult with her healthcare provider before receiving any new vaccinations or booster shots.

Pregnancy: Women who are pregnant or breastfeeding should not take Sarilumab, as it has not been studied in these populations and may pose risks to the developing fetus or nursing infant.

Allergies: Your mother-in-law should inform her healthcare provider if she has any allergies or a history of allergic reactions, as she may be at increased risk of developing an allergic reaction to Sarilumab or other medications used to manage RA symptoms.

Lifestyle factors: Your mother-in-law should continue to follow a healthy lifestyle, including regular exercise, a balanced diet, and stress management techniques, as these factors can help manage RA symptoms and improve overall health and well-being. She should also avoid smoking and excessive alcohol consumption, as these habits can worsen joint pain and stiffness in people with RA.

I hope this helps you.

Thank you.

Regards.