What is the reason for new wound during chemotherapy?

Hi,

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The most common causes for a wound at the operated or treated site is - osteoradionecrosis and recurrent cancer. From your description, it seems like the wound is an effect of chemoradiation, more specifically radiation. We call it osteoradionecrosis, a complication of radiation to the mandible bone. The mandible is also affected in the radiation field for all cheek cancers. There is a risk of overlying skin death resulting in a wound exposing the underlying bone. It may be conservatively managed for a small wound or require a flap to cover it. In the event of recurrence, a biopsy needs to be done, and based on the extent of the disease; further treatment can be planned. Kindly review with the oncologist who treated you before or any other surgical oncologist for appropriate physical evaluation, diagnosis, and treatment.