Can chemotherapy result in new wounds?

Q. What is the reason for new wound during chemotherapy?

Answered by
Dr. Nadiminty Raghuvamsi
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on Apr 06, 2016 and last reviewed on: Dec 18, 2021

Hi doctor,

My father had surgery for cancer and subsequent chemoradiation on the cheeks. After that, he developed a wound on the right cheek, which grew into a big hollow wound. Would you please help us?

#

Hi,

Welcome to icliniq.com.

The most common causes for a wound at the operated or treated site is - osteoradionecrosis and recurrent cancer. From your description, it seems like the wound is an effect of chemoradiation, more specifically radiation. We call it osteoradionecrosis, a complication of radiation to the mandible bone. The mandible is also affected in the radiation field for all cheek cancers. There is a risk of overlying skin death resulting in a wound exposing the underlying bone. It may be conservatively managed for a small wound or require a flap to cover it. In the event of recurrence, a biopsy needs to be done, and based on the extent of the disease; further treatment can be planned. Kindly review with the oncologist who treated you before or any other surgical oncologist for appropriate physical evaluation, diagnosis, and treatment.


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