Q. I am experiencing side effects of Doxycycline, which I took for UTI. Please help.

Answered by
Dr. Sadaf Mustafa
and medically reviewed by iCliniq medical review team.
This is a premium question & answer published on May 05, 2017 and last reviewed on: Dec 15, 2021

Hello doctor,

I have been sick with side effects from Doxycycline for two weeks. I had a UTI which has cleared. I have been to the doctor twice, they checked my urine, and there is no infection. I feel tired, have chills, I feel cold, have a back and joint pain. I do not have a fever. I have read that, sometimes it can last up to three weeks. Is it possible to last this long? My blood tests are also normal.



Welcome to

  • I understand that you had a urine test, but there are different types of urine test like a dipstick, which is done at the office, a complete analysis, which is done in the laboratory and a urine culture. I am more interested in the last two.
  • With all due respect to your doctor and you, Doxycycline may not be the best antibiotics to treat a urinary tract infection (UTI), unless a very specific bug is suspected like MRSA (Methicillin-resistant streptococcus aureus).
  • I will do my best to help you out here, I just need to gather some more information.
  1. Do you still have the urinary symptoms like going to the bathroom multiple times during a typical day and unable to hold the urine?
  2. Do you have night time symptoms like nausea or vomiting?
  3. Do you have a fever? I understand you have cold chills.
  4. What blood test was done? Was it a CBC (complete blood count)? Would you be able to share a copy?

Revert with more information to an internal medicine physician online -->

Thank you doctor,

I had two urine analysis done in the laboratory. The last one, which was done five days ago, showed no infection. I still have burning and frequent urination sometimes, especially during the night. The burning is not while urinating. The doctor told me I have dysuria. I do not have a fever, nausea, or vomiting. Can it still be an infection?



Welcome back to

  • There could be two possibilities.
  1. Interstitial nephritis, which means that there is no real infection but something is irritating your bladder, which could be food, medications, inflammation, and less likely a bladder polyp.
  2. Unresolved urinary tract infection.
  • I would suggest that you request your primary care physician to obtain a urinary culture for you and refer you to a urologist because you are still having these symptoms. I would also like your primary care doctor to check your CBC, kidney and liver function tests, vitamin D, vitamin B12 levels, diabetes and thyroid workup for you.
  • If you have not had a colonoscopy, mammogram, and pap smear, then that should also be done. It is crucial that you should have age appropriate cancer screening to make sure that your tiredness and fatigue is not because of a hidden cause.

If you can get a copy of these blood works and share it with me, I will be able to guide you.

For further queries consult an internal medicine physician online -->

Was this answer helpful?


Same symptoms doesn’t mean you have the same problem. Consult a doctor now!

Related Questions:
What are the small clustered cystic areas seen in the left breast.

They will examine and may do an ultrasound of pelvis to check ovaries and uterus ... Hello doctor, I have multiple small clustered cystic areas seen in the left breast ... But you should do a ba...   Read full

Please suggest medicines for parameters out of range in the blood test.

Firstly, urine analysis shows pus cells which points to urinary tract infection ... For the urinary tract...   Read full

How To Detect Breast Cancer?

For women less than age 35, a mammogram is done by ultrasound scan when we suspect a problem ... Breast cancer is now emerging as one of the leading causes of death in women ... A ...   Read full

Also Read Answers From:

ideaComprehensive Medical Second Opinion.Submit your Case

Also Read

Coronavirus Variant Arcturus: | Omicron XBB.1.16 Variant
Arcturus is an emerging variant of the Omicron virus that causes various symptoms and spreads rapidly across the world. ...  Read more»
Adrenaline Rush - Symptoms, Causes, Effects, and How to Control
Adrenaline is a hormone responsible for fight or flight response. It is also a neurotransmitter and medicine. It is also...  Read more»
Fatty Liver - Types, Symptoms, Stages, and Treatment
The liver is the largest gland in the body. Its primary function is to process the food and drinks we consume. and filte...  Read more»

Ask your health query to a doctor online?

Ask an Internal Medicine Physician Now

* guaranteed answer within 4 hours.

Disclaimer: No content published on this website is intended to be a substitute for professional medical diagnosis, advice or treatment by a trained physician. Seek advice from your physician or other qualified healthcare providers with questions you may have regarding your symptoms and medical condition for a complete medical diagnosis. Do not delay or disregard seeking professional medical advice because of something you have read on this website. Read our Editorial Process to know how we create content for health articles and queries.