Introduction:
Coenzyme Q10 is also called ubiquinone or coenzyme Q. It is naturally synthesized in the body and is oil-soluble. It is responsible for energy generation in the body. In addition to being a crucial component for mitochondrial electron transport chains, it is also important for the production of ATP (adenosine triphosphate). It carries the ability to recycle and regenerate other antioxidants. Coenzyme Q10, which is found in the mitochondria, is responsible for producing 95 percentage of the energy in the human body.
Peter Mitchell presented a theory on the electron transport chain in 1961, and for the same work, he was awarded the Nobel Prize in 1978. Coenzyme Q10 is present in three redox states. It plays a vital role in maintaining cardiovascular health and preventing neurodegenerative symptoms. Coenzyme Q10 is present in a significant amount of the heart muscle cells due to high energy demand. Coenzyme Q10, along with other medications, can help in improving heart health. A sufficient amount of coenzyme Q10 in the human body can also regulate high cholesterol levels.
What Is the Relation Between Coenzyme Q10 and Cardiovascular Diseases?
Coenzyme Q10 is present in a significant amount of the heart muscle cells due to high energy demand. Therefore, coenzyme Q10, along with other medications, can help in improving heart health. Many research papers have proven that people who take coenzyme Q10 supplements regularly after a heart attack (a cardiac condition due to reduced or lack of blood supply to the heart) show a reduced risk of a second heart attack, and symptoms of chest pain are also relieved.
Conventional medications for cardiovascular disorders, when prescribed with coenzyme Q10, have been noted to give much better results. Coenzyme Q10 also reduces fluid accumulation and thus improves symptoms of congestive heart failure by reducing swelling and fluid accumulation in the lungs and legs. The swelling reduction also makes breathing more manageable in these patients.
What Is the Role of Coenzyme Q10 in Hypertension Management?
Many research works have been carried out to know the significance of coenzyme Q10 in hypertension management. On regular consumption of coenzyme and Q10 supplements, a significant reduction in blood pressure has been noted. It takes around four to twelve weeks to emphasize visible changes or blood pressure reduction. There are no side effects associated with coenzyme Q10 consumption for hypertension management. It has been noted that coenzyme Q10 can reduce systolic blood pressure by 17 mm (millimeters) and diastolic blood pressure by 10 mm (millimeters) without any significant side effects.
What Is the Role of Coenzyme Q10 in Cholesterol Management?
Studies have shown that individuals with low coenzyme Q10 levels usually suffer from high cholesterol levels. The direct effect of coenzyme Q10 on cholesterol level reduction is yet to be established. It has been noted that drugs prescribed for lowering cholesterol levels usually reduce the coenzyme Q10 levels. In such cases, it is advisable to prescribe supplements of coenzyme Q10.
What Is the Role of Coenzyme Q10 in Maintaining Gum Health?
Swelling in gums, bleeding, pain, and redness are common periodontal problems in individuals with coenzyme Q10 deficiency. Currently, many clinical studies are going on to establish the role of coenzyme Q10 in improving periodontal health. Numerous studies have shown that using coenzyme Q10 supplements regularly improved periodontal health.
What Are the Benefits of Coenzyme Q10?
Following are a few expected benefits of coenzyme Q10:
-
Coenzyme Q10, along with other medications, can help in improving heart health.
-
On regular consumption of coenzyme and Q10 supplements, a significant reduction in blood pressure has been noted.
-
Studies have shown that individuals with low coenzyme Q10 levels usually suffer from high cholesterol levels.
-
Numerous studies have shown that ingesting coenzyme Q10 supplements routinely enhanced periodontal health.
-
Coenzyme Q10 is useful for reducing migraine symptoms.
-
Improves exercising ability.
-
Coenzyme has a significant anti-cancer effect.
-
Coenzyme Q10 helps in fatigue reduction as it increases blood flow.
-
The anti-aging effect is also noted.
What Are the Adverse Effects of Coenzyme Q10 Supplements?
Oral coenzyme Q10supplements can sometimes produce symptoms such as bloating, abdominal pain, nausea, and indigestion. These symptoms are usually noted in taking excessive supplements beyond the recommended dosage. It should also be contraindicated in individuals suffering from irritable bowel syndrome or colic disorders.
It is contraindicated to prescribe coenzyme Q10 supplements with the drug Warfarin. Coenzyme Q10 is structurally similar to vitamin K, and prescribing coenzyme Q10 with Warfarin has an antagonist effect on its activity. Coenzyme Q10 has antioxidant effects. So, it may lead to decreased efficacy of chemotherapy.
What Are the Dosage and Indications of Coenzyme Q10?
Coenzyme Q10 supplements are available in the form of capsules. One capsule per day is usually prescribed. These supplements are usually prescribed for conditions such as:
-
Myalgia (muscle pain without any underlying causes) is caused due to long-term use of statin.
-
Depletion in coenzyme Q10 levels due to aging.
-
Patients are suffering from chronic cardiovascular disorders.
-
Hypertensive (high blood pressure) patients.
-
Patients who are suffering from periodontal (supportive dental structures) diseases like gum bleeding and swelling.
-
People who experience chronic tiredness syndrome.
Recommended dosage of coenzyme Q10 supplements is 100 mg (milligrams). Its peak level occurs between five to ten hours. The plasma half-life of coenzyme Q10 Is approximately 49 to 125 hours. Excretion of the coenzyme Q10 is predominantly via the biliary tract.
Conclusion
Coenzyme Q10 produces 95 percent of the energy used by the human body. It is crucial for preserving cardiovascular health and reducing the signs of neurodegenerative disease. Coenzyme Q10 is present in a significant amount of the heart muscle cells due to high energy demand. Coenzyme Q10, along with other medications, can help in improving heart health. A sufficient amount of coenzyme Q10 in the human body can also regulate high cholesterol levels. In addition, Coenzyme Q10 helps in fatigue reduction as it increases blood flow. Recommended dosage of coenzyme Q10 supplements is 100 mg (milligrams). It is available in the form of capsules. One capsule per day is usually prescribed.
