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Wandering Atrial Pacemaker - Causes, Symptoms, Diagnosis, and Treatment

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A wandering atrial pacemaker is an atrial arrhythmia that occurs when the natural cardiac pacemaker site shifts between sinoatrial and atrioventricular nodes.

Medically reviewed by

Dr. Muhammad Zohaib Siddiq

Published At August 17, 2023
Reviewed AtAugust 17, 2023

What Is a Wandering Atrial Pacemaker?

A wandering atrial pacemaker is a specific arrhythmia that can affect the heart. A condition that affects the rhythm or rate of the heartbeat is known as an arrhythmia. There are wide varieties of arrhythmia, including an irregular beat, an extra beat, and a fast or slow heart rate.

What Are the Causes of This Condition?

A clump of cells known as the sinoatrial (SA)node can be found in the upper right quadrant of the heart. Regulation of the heartbeat commences from the SA node to other parts of the atria.

What Are the Symptoms of a Wandering Atrial Pacemaker?

It includes the following symptoms:

  • Fatigue: It is a temporary decrease in the irritability or function of organs, tissue, or cells after extreme stimulation or exercise. It is a symptom shared by various medical disorders, ranging in severity from minor to life-threatening.

  • Shortness of Breath: It is a disorder that causes constriction in the chest, a desire for oxygen, trouble breathing, shortness of breath, or the sensation of being suffocated. Several potential contributors to this illness include vigorous exercise, severe temperatures, obesity, and other medical disorders.

  • Dizziness: Dizziness is a general phrase referring to several sensations, including dizziness, unsteady, weak, or unstable. The most common reasons are a sudden reduction in blood pressure, dehydration, and other medical conditions such as heart disease, stroke, internal bleeding, and shock. Other medical conditions include shock.

  • Chest Pressure: The feeling of pressure in the chest is a non-specific sensation that can be brought on by a variety of conditions, including a heart attack, cardiac tamponade (in which fluid surrounds the heart and presses on it), or other issues related to the pericardium.

What Is the Diagnostic Method?

Those with tachycardia and an abnormally irregular rhythm associated with the underlying medical problem are most likely to have a wandering atrial pacemaker. Cardiac and pulmonary disease patients are also more likely to have this issue.

  • Electrocardiogram: An ECG demonstrating an atrial rate of more than 100 beats per minute in conjunction with three or more distinct P wave morphologies in the same lead is required to diagnose. This does not include the P wave that originates from the sinoatrial node. Although the PR and RR intervals are irregular, there is additionally an inconsistency in PP intervals, and even the baseline between P waves should be isoelectronic. Since the PR interval varies with the duration of the RP interval that came before it, this fluctuation in the PR interval was not included in the clinical guidelines.

  • Blood Investigation: If the arrhythmia continues to occur despite the therapy of the fundamental medical illness, blood count and plasma chemistry will be examined for signs of infection, anemic condition, or electrolyte imbalance, including hypokalemia and hypomagnesemia.

  • Other Diagnoses: The differential diagnosis involves sinus tachycardia with regular premature atrial contractions and atrial flutter with varying AV node conduction at consistent PP intervals and regular PP interval and flutter waves, atrial fibrillation with distinct P wave morphologies, and wandering atrial pacemaker with only a heart rate of the less than 100 beats per minute.

What Are the Risk Factors?

  • Sleep Apnea: Individuals with problems with their heart rhythm often have a medical condition known as obstructive sleep apnea (OSA). Even though OSA can cause arrhythmia due to acute mechanisms, such as the generation of negative intrathoracic pressure during futile efforts to breathe, arousal from sleep at the end of obstructive events, intermittent hypoxia, and surges in sympathetic activity, this condition can be a contributor to the disease. The OSA caused the heart to reorganize itself, increasing its sensitivity to arrhythmias due to sympathetic discharges that caused anomalies in the arterial system.

  • Chronic Obstructive Pulmonary Disease(COPD): Patients diagnosed with COPD are more likely to suffer from cardiovascular disease. Cardiovascular and chronic obstructive pulmonary disease (COPD) are proinflammatory states characterized by oxidative stress and accelerated aging. These characteristics are a probable reason for the higher risk of cardiovascular illness in COPD patients. The most prominent pathologic manifestation of COPD, hypoxia, affects the electrophysiology of the atrium, which has the potential to lead to the occurrence of arrhythmias. Both hypercapnia and hypoxemia, generated by COPD, can lead to the contracting of the pulmonary arterioles, which raises the blood circulation inside the pulmonary artery and may have other adverse effects on the right atrium. Both of these conditions are caused by the disease COPD. In addition, the increased pressure in the right atrium will drive the right atrium to expand, leading to hemodynamic abnormalities in the endocardial blood vessels and the resetting of blood flow, eventually leading to a greater susceptibility to arrhythmias.

  • Emphysema: It is a condition that affects the alveoli, which are found in the lungs. Inside the walls of the alveoli is where the respiratory gasses are constantly exchanged in the lungs. When someone has emphysema, their alveoli become unusually expanded, which damages their surfaces and makes it harder for them to breathe.

  • Chronic Bronchitis: Inflammation and irritation of the pulmonary passages are the two primary symptoms of chronic bronchitis. In addition, due to the discomfort caused by the tubes, mucus starts to accumulate, making it harder for the tubes to transfer oxygen and carbon dioxide gasses.

  • Asthma: In adults, asthma is characterized by a systemic inflammation that can be measured using biomarkers like C-reactive protein. Asthma is a chronic condition that causes respiratory tract inflammation. Both short- and long-acting beta-two agonists used in asthma treatment may raise the patient's chance of developing arrhythmias.

  • Drug Toxicity: Poisoning from various agents can lead to irregular heart rhythms, known as arrhythmias. These arrhythmias are brought on by certain cardiac features of the medications consumed, and as a result, they call for particular antidotes. For example, many drugs are responsible for ventricular arrhythmias, which can disrupt the balance because of medicine for the cardiovascular system.

How Can the Condition Be Treated?

The treatment is determined by the extent of the disease and the underlying ailment. There is currently no cure or treatment specifically designed for the illness. The illness does not manifest any symptoms; nevertheless, in severe cases, medication may be prescribed to relieve the clinical manifestations. It is possible to examine the insertion of a pacemaker for sinus node injury when dysfunction in the sinus nodes manifests as a wandering atrial pacemaker. A permanent pacemaker is a device that continually causes the cardiac muscle to contract by stimulating it with very low electrical impulses to maintain a regular heartbeat. A pulse generator and a wire that conducts impulses from the pulse generator to the cardiac muscles are both components of the pacemaker. The pacemaker is implanted in patients to ensure their hearts beat at a healthy and normal rate.

It is essential to thoroughly investigate and adequately manage the disease brought on by the underlying issue to improve the prognosis of the condition, as well as the treatment of it, and to reduce the likelihood that it will recur.

Drug toxicity can be handled with the assistance of a medical specialist, who may recommend that the patient's prescription dose be decreased or that the therapy be terminated.

Conclusion:

The term "wandering pacemaker" refers to an electrographic sequence of irregular, multiform, supraventricular beats with shifting P wave shape and varied PR intervals. This pattern can be found in some patients with heart conditions. The individual's clinical situation and the patient's features will dictate the specific management strategy that should be used with the patient. They are managed with the appropriate medication, and surgical treatment is necessary in extreme cases. The kind and severity of the ailment determine how they are managed.

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Dr. Muhammad Zohaib Siddiq
Dr. Muhammad Zohaib Siddiq

Cardiology

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