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Impact of Autoimmune Diseases on Mental Health

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Understanding the relationship between autoimmune disorders and mental health may lead to better overall results, diagnosis, and treatment.

Medically reviewed by

Dr. Vipul Chelabhai Prajapati

Published At March 21, 2024
Reviewed AtMarch 21, 2024

Introduction

A class of illnesses known as autoimmune disorders occurs when the body's immune system unintentionally targets its tissues, causing inflammation and other health problems. Even though physical symptoms are frequently the main emphasis, there is mounting evidence that autoimmune illnesses and their psychological manifestations are intricately related. This intricate interaction can substantially negatively affect a patient's general health and create particular difficulties for diagnosis and treatment.

What Are Autoimmune Diseases?

Many disorders fall under the umbrella of autoimmune diseases, including type 1 diabetes, lupus, multiple sclerosis, and rheumatoid arthritis. In these conditions, the immune system (meant to protect the body from foreign invaders like germs and viruses) mistakenly affects its cells as intruders from outside the body, which sets off a protracted inflammatory reaction.

Can Autoimmune Conditions Cause Mental Health Problems?

It makes sense that mental health problems could be caused by autoimmune disorders that directly damage the brain. For instance, autoimmune encephalitis and multiple sclerosis can result in psychosis or abnormal thinking that includes delusions and hallucinations. Numerous autoimmune diseases, including lupus, ankylosing spondylitis, and ulcerative colitis, are associated with depression and bipolar disorder, according to studies. Additionally, anxiety and despair are more common in those with autoimmune thyroid illness.

There are not all autoimmune disease sufferers with symptoms severe enough to warrant a mental health diagnosis. However, this does not mean that a person cannot still have some symptoms associated with mental health. For instance, a lot of individuals with autoimmune diseases report having trouble sleeping, feeling down, and generally having a worse quality of life in terms of their physical and mental health. In either case, when one has an autoimmune disease, it is critical to be aware of the signs of mental illness.

How Do Autoimmune Conditions Cause Mental Health Problems?

Autoimmune diseases can exacerbate mental health issues using complex and interrelated processes. Autoimmune disorders and mental health have a complex interaction that involves both direct and indirect impacts on the central nervous system. The following are some significant ways that autoimmune diseases might affect mental health:

Although the exact mechanism by which autoimmune diseases lead to mental health disorders is unknown, researchers have some theories:

  • Inflammation: The blood of individuals with autoimmune illnesses contains increased concentrations of cytokines that promote inflammation. These substances can alter brain chemicals that control mood and energy levels, in addition to causing inflammation in the body. Depression-like symptoms, including exhaustion and problems with eating and sleeping, can be brought on by this procedure.

  • Stress: Managing an autoimmune disease can be highly stressful, which can exacerbate mental health issues.

  • Drugs: Steroids and other medications used to treat autoimmune diseases can lead to side effects like psychosis and insomnia.

Can Autoimmune Conditions Cause Brain Fog?

Brain fog characterizes symptoms including foggy, forgetful, and trouble focusing. Brain fog is a symptom of various disorders, such as autoimmune diseases, moderate cognitive impairment, and postural tachycardia syndrome (POTS). Although the precise etiology of these symptoms is unknown, scientists have several possibilities. Those with autoimmune diseases may have brain fog for a variety of reasons, including:

  • Inflammation is brought on by the inflammatory condition that affects the brain.

  • Coexisting mental health issues, like sadness and anxiety.

  • Pain and stress issues medications for sleep.

Does Stress, Despair, or Other Mental Health Issues Cause Autoimmune Disease?

It is also possible for certain autoimmune illnesses to produce depression and vice versa. Research has indicated that depression may heighten the likelihood of developing specific autoimmune disorders, such as Crohn's disease, celiac disease, and Graves disease.

Although the exact cause of this is unknown, depression's psychological stress may be to blame. In general, stress can cause modifications to the brain and the body's nerves. These alterations in the nervous system may eventually have a deleterious effect on the immune system, resulting in autoimmune diseases. Therefore, reducing one’s stress may help avoid getting an autoimmune disease.

Autoimmune illnesses have been connected to numerous different mental health issues. Anorexia, bipolar disorder, autism, ADHD (attention deficit hyperactivity disorder), and schizophrenia were among the mental health conditions that researchers found to be more common in patients. These individuals were also more likely to have at least one autoimmune disease, such as psoriasis, type 1 diabetes, and Crohn's disease. An autoimmune disease diagnosis is more likely to be received by individuals suffering from post-traumatic stress disorder (PTSD).

How to Manage Mental Health Problems With an Autoimmune Disease?

When dealing with an autoimmune disease and mental health issues, a thorough and interdisciplinary approach is necessary. The following are some methods for enhancing mental health that people with autoimmune diseases may want to think about:

  • Create a Support Network: People should have a robust network of friends, family, and medical professionals. Talking about their experiences with like-minded people might help them feel less alone and offer emotional support.

  • Become Informed: People should know the autoimmune condition and its possible effects on their mental well-being. Awareness of the relationship between their illness's emotional and physical components can enable patients to make informed health decisions.

  • Collaborative Healthcare: Assist a group of medical experts, such as neurologists, rheumatologists, and mental health counselors. The comprehensive treatment of both the autoimmune and mental health elements is guaranteed via collaborative care.

  • Frequent Medical Check-Ups: To monitor and treat the autoimmune disorder, schedule routine medical check-ups with the healthcare providers. Managing physical ailments effectively can have positive effects on mental health.

  • Psychotherapy: Engage in psychotherapy, such as counseling or cognitive-behavioral therapy (CBT). These therapeutic modalities can assist people in managing their emotions and stress and creating coping mechanisms for the difficulties of having a chronic condition.

  • Medicinal Management: Consult a psychiatrist to discuss pharmaceutical alternatives if mental symptoms are severe. Certain drugs can help in the treatment of anxiety, mood disorders, or cognitive impairment. To prevent any interactions, ensure the healthcare providers know one’s prescriptions.

  • Stress Management Techniques: Engage in stress-relieving activities like yoga, deep breathing exercises, mindfulness, and meditation. Stress reduction is essential for maintaining good physical and mental health; these techniques can assist.

  • Sustain a Healthful Lifestyle: Make good eating, frequent exercise, and enough sleep one's priorities. These elements can favor physical and mental health and contribute to overall well-being.

  • Keep an Eye on Mental Health: If people observe any notable changes in their mood, thinking, or emotional stability, be proactive in getting help. The development of mental health issues can be stopped with early intervention.

Recognize the value of self-care and take breaks to practice it. Make time for enjoyable hobbies, take breaks when necessary, and prioritize mental and emotional health. It is critical to balance the demands of treating a chronic condition and self-care.

Conclusion

In summary, the complex interplay between autoimmune disorders and mental health highlights the significance of treating both the physiologic and psychological components of these illnesses. Their mental health dramatically impacts people's overall quality of life as they manage the challenges of having an autoimmune disease.

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Dr. Vipul Chelabhai Prajapati
Dr. Vipul Chelabhai Prajapati

Psychiatry

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