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Connection Between Kidney Disease and Oral Health: Understanding the Intricacies

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Oral health and kidney disease are interrelated. Hence, proper dental care is essential for patients with kidney disease.

Written by

Dr. Pallavi. C

Medically reviewed by

Dr. Ummah Mohammad

Published At February 5, 2024
Reviewed AtFebruary 5, 2024

Introduction:

The entire human body is interdependent, including the relationship between the health of the kidneys and the oral cavity. Like the rest of the body, the oral cavity is vulnerable to illness and infection when there is a kidney problem. Toxins are removed from the blood by the kidneys, transforming waste into urine. Oral health is one of the many health systems that may suffer if this process is disrupted or stopped. This article examines how human bodies might be affected by dental health and vice versa, including the possibility that a tooth infection may have an impact on the kidneys.

How Does Oral Health Affect Kidney Diseases?

In a short period, kidney diseases can go from being minor to potentially fatal. Renal failure, often known as kidney failure, is the inability of one or both kidneys to function normally. In certain situations, the problems can be solved quickly and temporarily with brief treatments.

Kidney failure of any kind can be detrimental to one's oral health. Medical terminology describes the mucosa, or inner lining of the mouth, as developing red sores with a bad stench.

Renal osteodystrophy is a bone condition that can potentially be brought on by kidney failure. The renal malfunction that results in a deficiency of calcium and phosphorus quickly demineralizes the mouth cavity. Teeth might fall out due to the weakening of the jaw and the bones that support the teeth.

Patients with modest to severely incapacitating medical issues frequently worry about kidney disease and tooth extractions. Oral infections brought on by dangerous microorganisms may result in extractions. An oral infection's early inflammation can swiftly develop into a persistent infection that is too strong for the body to fight.

Chronic dental infections not only cause pain and trouble chewing but also spread like wildfire throughout the body and cause foul breath. Weak immune systems prevent renal disease patients from effectively combating the illness. Additionally, kidney drugs might impede the body's defense system's ability to repair.

Renal function is continuously lost in those with chronic kidney disease, often known as chronic kidney failure. The kidneys filter toxins, and when the kidneys malfunction, the body suffers, including a person's dental health.

Infections, inflammation, and artery hardening can result from kidney disorders. These systemic effects might soon lead to tooth deterioration and loss. The immune system is weakened by chronic renal disease, which raises the risk of oral infections. Additional oral health problems associated with chronic renal disease include mucosal lesions and periapical lesions.

What Are the Oral Manifestations of Kidney Disease?

Patients with chronic kidney disease (CKD) may experience intraoral changes. These include

Uremic Stomatitis: Uremic stomatitis, is frequently linked to chronic renal failure that goes untreated. Uremic stomatitis is a painful lesion brought on by high blood urea nitrogen levels. There are four possible manifestations of uremic stomatitis. These include hemorrhagic, nonulcerative, ulcerative, and hyperkeratotic. The oral mucosa may be covered in thick gray exudate or exhibit red mucosal ulcers. White lesions are seen in hyperkeratotic and nonulcerative forms. Lesions with hyperkeratotic tendencies are more frequently observed on the tongue and floor of the mouth. Applying topical anesthetics, sucking on ice chips, or using a gently acidic mouth rinse (such as diluted hydrogen peroxide) can all help reduce the pain associated with uremic stomatitis.

Xerostomia and Altered Taste: Increased uremic levels in the salivary glands, which result in an elevated pH and an ammonia-smelling odor or metallic taste, are frequently observed in individuals with Stage 4 chronic kidney disease.

Mucosal Petechiae and Ecchymosis: A reduction in platelet factor III is the source of petechiae and ecchymosis, which are frequently observed on the tongue, soft palate, and buccal/labial mucosa.

Renal Osteodystrophy: Renal osteodystrophy is a bone disease that can result from parathyroid dysfunction or from the kidneys' inability to maintain normal levels of calcium, phosphorus, and vitamin D. Loss of the lamina dura and "brown tumors" are symptoms of renal osteodystrophy. Renal osteodystrophy presents as a ground glass look on X-rays in adults and children. Possible outcomes are tooth mobility, significant periodontal damage, and delayed tooth eruption.

Does Bad Dental Health Cause Kidney Problems?

The state of the mouth immediately affects the renal health concerns that are brought up. Periodontal disease, tooth decay, and gum disease are dental disorders that may cause issues with kidney function. Research has demonstrated a clear link between kidney-related disorders, such as chronic illnesses, and mouth inflammation.

According to one study, there was a 3 percent reduction in renal function for every 10 percent rise in gum infection. Subsequent research revealed that study participants experienced a 25 percent increase in periodontal inflammation for every 10 percent decline in renal function.

Periodontal disease is one prevalent dental illness. The gum tissues are infiltrated by bacteria, which leads to inflammation and infection. The mouth's soft tissues may sustain harm from this gum disease. More severe diseases may cause the bone structure to deteriorate and lead to tooth loss. Because periodontal disease may spread through the circulation, it can negatively impact the body's key organs.

Are Dental Procedures Safe for People With Kidney Diseases?

Ninety percent of chronic kidney disease patients have the following oral health issues: mucositis, glossitis, uremic stomatitis, xerostomia, and oral malodor. It should be advised to use fluoride applications, toothpaste, and mouth rinses. Nevertheless, because renal insufficiency might result in fluoride retention, oral health practitioners should exercise caution when administering systemic fluoride supplements to children with Chronic kidney disease.

If one has any kind of kidney illness, it is essential to continue having regular dental checkups since excellent tooth health is essential for healthy kidney function. Dental hygienists and dentists can evaluate, manage, and choose the best treatment assistance for patients with chronic kidney disease (CKD) by using caries risk assessment.

Together with the dentist, discuss the choices for developing a dental care plan to address oral health concerns while causing the least amount of kidney harm possible. A prescription antibiotic may be needed if dental work or surgery is indicated in the days or weeks preceding treatment. This can lessen the possibility that an infection will spread to the kidneys. Patients on dialysis must plan any dental work on a day when they are not getting renal therapy.

What Are Precautions to be Taken for Individuals With Kidney Transplants?

A comprehensive dental examination is part of the evaluation and assessment process for those needing a kidney donation. This is to ensure there are no dangers of infection from potential tooth decay or gum disease, which might cause a delay or even stop the transplant process.

Certain immunosuppressive drugs must be used before a kidney transplant to improve the body's likelihood of accepting the new organ. These same drugs diminish the body's capacity to fight infection. Pre-transplant evaluations concentrate on all potential sources of infection.

Patients are advised to wait three months following their donation before undergoing dental work, including routine cleanings, to avoid issues. Under the guidance of their dentist and doctor, kidney transplant recipients can review their dental care regimen once the prescribed amount of time has passed. Generally, the recommended biannual dental checkups can be expanded to a bimonthly or trimonthly session.

Conclusion:

Healthcare professionals should acknowledge the reciprocal association between renal illness and dental health. Early identification and treatment of oral health issues can enhance overall health outcomes for those with kidney disease. For those with chronic kidney disease (CKD), maintaining oral health requires routine dental examinations and proper oral hygiene habits.

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Dr. Ummah Mohammad
Dr. Ummah Mohammad

Dentistry

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