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Painful Urination - An Overview

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Painful or uncomfortable urination is referred to as dysuria. Dysuria, which feels like burning, is typically brought on by urinary tract bacterial infections.

Published At December 22, 2023
Reviewed AtDecember 22, 2023

What is Painful Urination?

An excruciating or burning sensation while urinating might be caused by a variety of mild to severe medical conditions. The condition known as painful urination is referred to by its clinical description as dysuria. Pain during urination is commonly felt through the urethra, the pathway that conveys urine from the bladder to the outside of the body or in the region around the genitals.

What Are the Causes Of Painful Urination?

Most often, painful urination has been triggered by a disease or infection in the urinary tract, including:

  • Urinary tract disease.

  • Swelling and inflammation of the channel that transports urine from the body (urethra).

In women, painful urination may result from:

  • Menopause: It causes alterations in vaginal tissue (atrophic vaginitis).

  • Herpes Infection: Herpes simplex is the most prevalent form of the herpes virus. If infected by the herpes simplex virus in the event that they have ever had a fever blister or a cold sore. Herpes simplex virus type 1 (HSV-1) is the causative agent in the majority of cases of cold sores.

  • The Irritation of Vaginal Tissue: It is brought on by bubble baths, fragrances, and lotions.

  • Vulvovaginitis: It is characterized by yeast and additional infections that affect the vulva and vagina.

These are additional causes of unpleasant urination:

  • Cystitis Interstitial: Interstitial cystitis (IC), commonly known as bladder pain syndrome, is generally a disorder that causes painful urine symptoms and is characterized by an extended duration of the condition's effects.

  • Prostate Inflammation (Prostatitis): Inflammation is the typical symptom of prostatitis, which is a condition that affects the prostate gland. It is common for prostatitis to make urinating painful or difficult, in addition to causing pain in the groin, pelvic region, or genitals.

  • Radiation Cystitis: Injury to the membrane of the bladder caused by pelvic radiation therapy.

  • STI: Infections that are transmitted sexually (STIs), such as gonorrhea (sexually transmitted infection caused by bacterium Neisseria gonorrhea) and chlamydia (sexually transmitted infection caused by the bacterium Chlamydia), are prevalent.

  • Bladder Contractions: Spasms of the urinary bladder occur while the bladder contracts involuntarily, causing urination.

What Are the Symptoms of the Condition?

According to the underlying cause of dysuria, additional symptoms may accompany urinary discomfort. Symptoms may consist of:

  • Lower Urinary Tract Infection (Cystitis): Persistent urination, a strong urge to urinate, loss of bladder control, discomfort in the lower front abdominal area near the bladder, cloudy urine, a strong odor, and bloody urine.
  • Pyelonephritis: In upper urinary tract infections, there is upper back pain, high fever with trembling shivers, dizziness, vomiting, cloudy urine, frequent urination, and an urgent need to urinate.

  • Urethritis: It is characterized by urethral discharge, redness around the urethral orifice, frequent urination, and vaginal discharge. Partners of individuals with urethritis caused by a disease that can be transmitted sexually are frequently asymptomatic.

  • Vaginitis: Pain, tenderness, or irritation in the vagina; abnormal or offensive vaginal discharge or odor; pain or distress during sexual activity.

What Are the Diagnostic Methods?

  • History: The history of the present illness will involve the duration and occurrence of symptoms. Important concomitant signs include fever, pain in the side of a person from the ribs to the hip, urethral or vaginal discharge, along with bladder discomfort, frequency, urgency, or blockage symptoms. Patients would be questioned about the color, clarity, and odor of their urine, as well as the consistency and type of discharge. Clinicians should also inquire whether a patient has recently engaged in unprotected sexual activity, applied irritants to the perineum, undergone urinary instrumentation, or is pregnant.

In the patient's past medical history, previous urinary infections, including those that occurred during childhood, as well as any known abnormalities of the urinary tract, such as congenital urinary tract malformations or the past development of kidney stones, should be noted. As is the case with any potentially contagious condition, it is essential to have previous evidence of an immunocompromised state or a recent stay in the hospital.

  • Review of the Systems: The symptoms that point to a possible cause. These symptoms include discomfort in the back or joints, irritation of the eyes (connective tissue disorder), and gastrointestinal symptoms such as diarrhea (reactive arthritis). A review of any food or drink that may be contributing to the symptoms is also required.
  • Examination of the Body: The examination involves an evaluation of the patient's vital signs, focusing special attention on fever. Examine the skin, mucosa, and joints for lesions suggestive of reactive arthritis, such as conjunctivitis (pink eye refers to an infection of the thin membrane that lines the inside of the eyelid and the globe of the eye known as the conjunctiva.) buccal ulcers (open wounds that can be rather unpleasant and can appear anywhere inside the mouth. They are often either red or yellow in color). Cold sores, on the other hand, are triggered by a virus and occur on the outside of the lips), and vesicular lesions (when fluid is trapped under the outer layer of skin (epidermis), it creates a bubble-like sac that is known as a vesicle, which is additionally known as a blister or a vesicular lesion it is also known as blisters), along with crusting lesions in the palms and soles, along with around the nails, and joint tenderness. The side of a person from the ribs to the hip is palpated for tenderness in the region of the kidneys. Over the bladder, the abdomen is examined for tenderness.

Women undergo a pelvic exam to detect perineal inflammation or lesions, as well as vaginal or cervical discharge. Instead of performing a second examination, a moist mount and a swab to be tested for sexually transmitted infections (STIs) should be obtained.

Men should have an external examination to identify penile lesions and secretion; the region beneath the foreskin must be inspected. To detect tenderness or enlargement, the testicles and epididymis are palpated. Examining the prostate's size, consistency, and tenderness through rectal palpation.

Which Are the Tests To Rule Out The Cause Of Painful Urination?

  • Urine Culture - In individuals at risk for multidrug-resistant illnesses, urine culture is advised.

  • Dipstick Test - Dipstick testing for white blood cells (WBCs).

  • Urinary Tract Infection - UTI during pregnancy may raise the risk of preterm labor or premature rupture of the membranes; hence, pregnant women are tested. Wet mounts are needed for vaginal discharge. Due to the non-typical presentation of many infected patients, doctors frequently obtain cervical (women) or urethral (men) exudate for STI testing (gonococcus and chlamydia culture or PCR).

  • Other Tests- STIs, vulvovaginitis, prostatitis, tuberculosis (TB), tumors, interstitial nephritis, and other conditions might generate WBCs in sterile cultures. In patients with no WBCs and sterile cultures, red blood cells on a urinalysis may indicate malignancy, calculus, a foreign body, glomerular abnormalities, or recent urinary tract instrumentation.

  • Cystoscopy and Imaging Test - Cystoscopy and imaging of the urinary tract may be recommended for individuals with no reaction to antibiotics, recurrent symptoms, or hematuria with no disease to check for blockage, anatomic abnormalities, malignancy, or other issues. Men experiencing persistent lower tract infections or polymicrobial infections should explore the rectovesical fistula. Males, older patients, pregnant women, and patients with persistent and recurrent dysuria need additional care and a more complete assessment.

What Are the Warning Signs of the Disease?

Particularly alarming are the following findings:

  • Fever with the side of the ribs to the hip discomfort or tenderness.

  • Immunocompromised patient.

  • Recurring infections (including common pediatric infections).

  • Abnormality of the urinary tract.

  • Male genitalia.

How Are The Causes Of Painful Urination Treated?

The treatment of dysuria is contingent upon its underlying cause:

  • Cystitis and Pyelonephritis - These variable infections, which are typically caused by bacteria, are treatable with oral antibiotics. For significant pyelonephritis characterized by elevated fever, shivering shivers, and vomiting, antibiotics may be administered intravenously (IV).
  • Urethritis - Antibiotics are utilized to treat urethritis. The specific kind of antibiotic prescribed for urethritis depends on the underlying infection.

  • Vaginitis - Vaginosis is treated with antibiotics for trichomoniasis (an infection that is caused by the parasite Trichomonas that typically affects the digestive system, the vaginal tract, or the urinary tract.) and bacterial vaginosis (bacterial vaginosis is a form of vaginal inflammation that is brought on by an excess of bacteria that is normally prevalent in the vagina, which throws off the vagina's natural equilibrium.)

  • Yeast Infection - Yeast infections are managed with antifungal medications, either orally or vaginally, in the form of a suppository or cream.

When an individual is sexually active while being treated for dysuria triggered by an STD, sexual partners must also be treated.

Conclusion

Urination pain is dysuria. It is common. Urine irritates urethral mucosa, causing dysuria. Detrusor contractions and urethral peristalsis activate submucosal pain receptors, generating urination pain or burning. Dysuria's causes vary. Dysuria is neither interstitial cystitis, prostatitis, or suprapubic/retropubic discomfort. The cause determines dysuria prognosis. Early diagnosis and treatment of most dysuria causes inflammatory and non-inflammatory improves results. Urogenital sepsis is better than other systemic infections. Renal failure and ESRD can result from stones, persistent infections, and benign prostatic enlargement. Untreated UTIs during pregnancy can endanger mother and child. Renal or bladder malignancies can cause dysuria. Early diagnosis, therapy, and comprehensive follow-up improve prognosis. Delayed diagnosis increases recurrence and worsens prognosis.

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Dr. Tuljapure Samit Prabhakarrao
Dr. Tuljapure Samit Prabhakarrao

Urology

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