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RENAL Nephrometry Score

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RENAL nephrometry score is a classification system used to standardize the assessment of anatomical features of kidney tumors.

Medically reviewed by

Dr. Yash Kathuria

Published At March 6, 2023
Reviewed AtMarch 6, 2023

What Is RENAL Nephrometry Score?

RENAL nephrometry score is a reproducible classification system used to assess the anatomical features of renal (kidney) tumors and standardize the assessment criteria. The assessment system is developed based on the five different reproducible characteristic features that highlight the anatomy of a solid kidney mass. The classification system was developed by the researchers Kutikov and Uzzo.

The RENAL (radius of the tumor mass, exophytic or endophytic growth properties, proximity of the tumor to the collecting duct or sinus in millimeters, anterior or posterior location in terms of polar lines) nephrometry scoring classification system was later introduced as a reproducible objective system to highlight the salient features of the renal (kidney) tumor anatomy.

What Is the Purpose of the RENAL Nephrometry Scoring System?

Based on cross-sectional image findings, the scoring system was typically developed to categorize kidney tumor masses into low, intermediate, and high complexity. Its purpose is to aid decision-making, counseling of the patient, surgical planning by the doctor, patient follow-up post-surgery, and academic reporting of renal tumors.

What Is the RENAL Nephrometry Classification?

The scoring is developed depending on the five basic salient features of the renal tumor mass. RENAL is an easy and simple-to-remember acronym for the five radiological features that are scored as follows:

  • Radius (Maximum Diameter) In Centimeters (CM) In Any Axis:

    • ⩽4: 1 point.

    • >4 but <7: 2 points.

    • ⩾7: 3 points.

The “R” descriptor denotes the maximum diameter of the mass. For example, a radius of 4 centimeters was considered the maximum size in dimensions for partial nephrectomy until recently. Lesions that are less than or equal to four centimeters (≤ 4 cm) are assigned 1 point, those less than four but greater than seven centimeters (> 4 but < 7 cm) are assigned 2 points, and those that are greater than or equal to seven centimeters ( ≥ 7 cm) are assigned 3 points.

  • Exophytic or Endophytic Tumor Location:

    • ⩾50% exophytic: 1 point.

    • <50% exophytic: 2 points.

    • 100% endophytic: 3 points.

The “E” descriptor signifies the exophytic or endophytic location of the tumor mass. Tumor lesions, predominantly endophytic, pose a greater surgical threat than exophytic ones. Lesions projecting more than 50 % outside the cortex of the kidneys are assigned 1 point, lesions less than 50 % are assigned 2 points, and tumor lesions that are completely endophytic are assigned 3 points.

  • Near Proximity to the Renal Collecting Duct System or Renal Sinus:

It is measured in millimeters as the shortest distance from the lowest point of the tumor mass.

  • ⩾7: 1 point.

  • >4 but <7: 2 points.

  • ⩽4: 3 points.

The “N” descriptor highlights the nearest proximity to the collecting duct system measured in millimeters (mm). It is best determined on excretory images. Tumors are subdivided into three categories:

  • Tumors seven millimeters or greater from the collecting duct system or renal sinus are assigned 1 point.

  • Tumors greater than four but lesser than 7 millimeters are assigned 2 points.

  • Tumors four millimeters or less from the central duct collecting system are assigned 3 points.

  • Anterior or Posterior Location:

It is assessed on axial imaging. The “A” descriptor denotes the anterior or posterior location of the tumor. No point value is assigned to it. For example, if the tumor typically lies on the kidney’s ventral surface, the anterior (a) descriptor is denoted. Tumors on the dorsal surface of the kidney are denoted as posterior (p). However, tumors that do not fall into these categories are designated “x.”

  • Descriptors: “a” (anterior), “p” (posterior), or “x” (neither).

  • ​​Location Relative to the Renal Poles:

The “L” descriptor denotes the tumor location concerning the polar renal lines.

  • A tumor entirely below the inferior pole or above the superior pole is assigned 1 point.

  • If the tumor mass crosses the polar line, it is designated by 2 points.

  • If more than 50 % of the tumor mass lies across the polar line or is entirely within the polar lines, it is denoted by 3 points.

  • The h suffix is designated if the tumor mass touches the primary renal artery or renal vein.

What Is the RENAL Nephrometry Score Grading?

  • A score of 4-6: low complexity renal tumor.

  • A score of 7-9: moderate complexity renal tumor.

  • A score of 10-12: high complexity renal tumor.

When Is the RENAL Nephrometry Score Used?

Patients having renal tumor mass can benefit from the RENAL Nephrometry score in determining the treatment. The score quantifies the typical features of renal tumor mass anatomy objectively and reproducibly. The scoring system standardizes the diagnosis of kidney tumor masses and effectively stratifies the type of treatment that should be given. Therefore, it has tried to objectify the subjective measures in the treatment part. Hence, it is especially useful in patients with renal tumors to aid doctors in determining the best treatment modality.

What Are the Benefits of the RENAL Nephrometry Score System?

The system was developed to objectively standardize the crucial nephrometry scoring anatomical features of the kidney tumor mass. It provides the following benefits:

  • Provides a simple, reproducible method for classifying renal tumor masses according to the complexity of the anatomical features.

  • Helps to stratify the renal tumor masses into low, medium, and high-complexity tumors. The higher the complexity of the tumor mass, the poorer the prognosis with invasive biological tumor behavior and challenging surgery and clinical outcomes.

  • The grading system can be used to evaluate, plan, and standardize medical literature reporting preoperatively by the surgeon.

  • Does not prevent the requirement of viewing the imaging before surgical operation.

Conclusion

To conclude, the RENAL nephrometry scoring system is an easy and simple methodology to stratify complex renal tumors based on their grading. The system helps the surgeon plan the treatment, decision-making, and patient counseling and provides a standardized platform for academic medical reporting. The RENAL nephrometry score correlates with long-term clinical outcomes and prognosis. However, the grading system does not include kidney abnormalities that may contribute to surgical morbidities, such as fusion or duplication. The radiologists that interpret the data will find the nephrometry scoring system simple. Also, the salient features of a renal tumor are reported for surgical planning.

Frequently Asked Questions

1.

What Is the Renal Nephrometry Score of 7?

The renal nephrometry score is used to assess the anatomical features of the renal tumor. It is based on five reproductive features characterizing the anatomy of the renal mass. The healthcare providers determine the tumor complexity using this scoring system. The score between seven and nine refers to moderate complexity. 

2.

What Is Nephrometry?

The tumor’s Nephrometry score is a systematized and quantifiable approach to determining the relevant anatomical features of the tumor. This helps stratify the solid renal mass into low, intermediate, and high complexity categories. This tool effectively determines the best surgical approach, type of ischemia during nephrectomy and technical problems. 

3.

What Is the Normal Limit for Nephrometry Method?

A nephrometry score is used to assess the tumor complexity based on the anatomical features. The scoring system is discussed below.
- A nephrometry score of 4 to 7 indicates low complexity.
- A score of 7 to 9 indicates moderate complexity.
- A score of 10 to 12 indicates high complexity. 

4.

What Indicates a High Score of Nephrometry?

The nephrometry scoring system helps predict the requirement for total nephrectomy or its conversion to open surgery. A score greater than nine indicates high-complexity tumors associated with renal unit loss or renal function decline. This cutoff score usually signifies a fourfold marked chance of the transformation from a partial to a radical procedure in the management of renal tumors

5.

What Are the Two Types of Nephelometry?

Nephelometry is used to assess the antigen and antibody. But this is generally fine with the antibody as the reagent, while the patient’s antigen is undetermined. 
 
The two types of tests include the following.
- Kinetic nephelometry.
- Endpoint nephelometry. 

6.

What Is the Significance of the Nephrometry Score?

The renal nephrectomy scoring unit was developed to address and catalog the solid renal mass (renal tumors) into low, intermediate, and high complexities. This scoring is fine based on the findings from the cross-sectional imaging. The main objective of this scoring system is to help in the decision-making, planning of surgery, patient counseling, and follow-up. 

7.

What Is the Diagnostic Tool for Nephrectomy?

Before considering the nephrectomy procedure, the patients are asked to undergo a general and metastatic assessment. The only valuation includes a complete blood count, urine analysis, liver function tests, kidney function tests, bleeding profile, and serum calcium assessment. The surgeon also recommends imaging tests. 

8.

What Is the Typical Indication of Nephrectomy?

The general indication of nephrectomy is the treatment of kidney cancer and the removal of benign tumors. 
 
The other indications include:
- Renal stone-related etiology.
- Irreversible kidney damage from obstruction, calculus, and chronic infection. 

9.

What Is the Risk Associated With Nephrectomy?

The risks and complications associated with nephrectomy surgery include the following.
- Infection.
- Postoperative pneumonia.
- Bleeding often requires a blood transfusion. 
- Injury to nearby structures.
- Allergic reaction to anesthesia.

10.

What Is the Success Rate of the Procedure Nephrectomy?

Nephrectomy refers to the surgical removal of the kidney. The procedure is indicated for treating kidney cancer and other significant conditions, like injuries and diseases. This procedure is also fine to remove the normal functioning of healthy kidneys from the donor for kidney transplantation. The survival rate was about 90 to 95 percent following a partial nephrectomy. 

11.

What Is the Average Age for a Procedure Nephrectomy?

A nephrectomy is a surgical procedure carried out to remove the kidney. This is indicated by kidney cancer and significant kidney damage. Most individuals with renal cancer are older. The average age when they get diagnosed is around 64 years, with most individuals getting diagnosed within 65 to 74 years. The median age for people getting nephrectomy is 64 years. 

12.

Is Nephrectomy a Complicated Surgery?

A nephrectomy indicates the surgical removal of the kidneys. A nephrectomy is generally considered a safe procedure. But, like other surgeries, nephrectomy also carries certain risks and complications. Partial nephrectomy is not a major surgery, while radical nephrectomy is a major intervention unless the tumor has not spread. 

13.

What Are the Precautions to Be Taken After Nephrectomy?

The following includes the post-operative care for a nephrectomy.
- One should only lift heavier items weighing up to 10 pounds for a minimum of six weeks.
- Avoid strenuous activities like weightlifting and heavy physical exercises for at least six weeks. 
- Drink plenty of fluids.

14.

What Is the Right Position for Nephrectomy?

A nephrectomy is a surgical procedure to remove the kidney. The patient is placed at the corner of the operating table. For laparoscopic nephrectomy procedures, the supine position is considered first for IV access and induction of general anesthesia. Hence, the patient is allowed to lie on the side for this procedure. 
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Dr. Yash Kathuria
Dr. Yash Kathuria

Family Physician

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