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Infantile Acrocyanosis - Types, Causes, Symptoms, Diagnosis, and Treatment

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Infantile acrocyanosis is a condition that can affect newborns, and It is characterized by a bluish discoloration of the skin, usually on the hands and feet.

Medically reviewed by

Dr. Veerabhadrudu Kuncham

Published At April 6, 2023
Reviewed AtApril 6, 2023

Introduction:

Infantile acrocyanosis is a benign skin condition that typically affects newborns. It is characterized by a bluish tint on the baby’s face, ears, hands, and feet. This discoloration is caused by narrowing the blood vessels, resulting in poor circulation. Infantile acrocyanosis is usually harmless and disappears within a few weeks of birth. However, in rare cases, it can be a sign of an underlying medical issue and may require further testing or treatment.

What Are the Types of Infantile Acrocyanosis?

Acrocyanosis is characterized by blue discoloration of the extremities, primarily the hands and feet. It is caused by reduced circulation in the affected areas. There are two types of acrocyanosis: primary and secondary.

  • Primary Acrocyanosis: It is a common condition that usually affects newborns and resolves without treatment within the first few weeks of life. It occurs when the baby is exposed to cold temperatures in the delivery room, causing their circulation to slow down temporarily. They can result in bluish discoloration of the hands, feet, and occasionally the ears and nose.

  • Secondary Acrocyanosis: It is caused by an underlying medical condition, such as Raynaud’s disease, peripheral vascular disease, or diabetes. Symptoms of secondary acrocyanosis may last for months or years and can be accompanied by other signs and symptoms, such as numbness or tingling in the affected area. Treatment depends on the underlying cause.

What Causes Infantile Acrocyanosis?

Infantile Acrocyanosis is a condition that typically occurs when there is an increased release of catecholamines due to intense cold or emotional distress. This increased release of catecholamines results in vasoconstriction, or narrowing of the blood vessels, which leads to blue discoloration of the skin. In addition to intense cold or emotional distress, other potential causes of infantile Acrocyanosis include:

  • Hypothyroidism: Low thyroid hormone levels can constrict blood vessels, which can cause infantile acrocyanosis.

  • Congenital Heart Defects: Congenital heart defects can also cause infantile acrocyanosis by decreasing the amount of oxygen in the blood circulating the body.

  • Anemia: Anemia can lead to low levels of hemoglobin in the blood, which can cause vasoconstriction (the narrowing of blood vessels caused by the contraction of small muscles in their walls) and leads to infantile acrocyanosis.

  • Genetic Predisposition: Infantile acrocyanosis can also be caused by a genetic predisposition.

What Are the Symptoms of Infantile Acrocyanosis?

Infantile Acrocyanosis is a condition that is characterized by blue-tinged skin on the hands, feet, and ears. Symptoms of this condition include:

  • Blueness in the skin and nail beds.

  • Coldness to the touch.

  • Occasionally a bluish tint to the mucous membranes.

The affected area may also feel numb or have a tingling sensation. This condition is more common in newborns and infants, although it can occur in children up to two years of age.

The symptoms of infantile acrocyanosis may vary from person to person, but generally, the bluish tint to the skin is the most noticeable symptom. Other symptoms may include coldness to the touch and a tingling or numb sensation in the affected areas. The blue discoloration usually disappears within an hour or two without any treatment. However, it is important to note that medical attention should be sought while this condition is not serious and usually resolves without treatment if the blueness persists or worsens.

How to Diagnose Infantile Acrocyanosis?

A physical examination and testing can make the diagnosis of infantile acrocyanosis.

  • Physical Examination: During the physical examination, the doctor will look for signs of blue-tinged skin around the baby’s extremities, especially their hands, feet, ears, and nose.

  • Testing: Besides a physical examination, the doctor may order tests to confirm a diagnosis of infantile Acrocyanosis. These tests may include the following:

    • A complete blood count (CBC) to rule out any other underlying conditions; an arterial blood gas test to measure oxygen levels in the blood

    • An electrocardiogram (ECG) checks for any irregularities in the heartbeat.

How Is Infantile Acrocyanosis Treated?

Treatment of infantile acrocyanosis typically involves making lifestyle changes to reduce the risk of developing the condition. These may include wearing warm clothing, avoiding cold environments, and keeping the baby’s hands and feet warm at all times. In addition, some parents may use topical creams or ointments designed to dilate the blood vessels in the area.

In cases where the symptoms become severe or persist for long periods, medical treatment may be necessary. They can include medications such as antihistamines or corticosteroids designed to reduce inflammation.

In some cases, phototherapy (or light therapy) may be recommended. This process exposes the child’s skin to ultraviolet light, which helps reduce inflammation and improve circulation.

In cases where the cause of acrocyanosis is found to be due to an underlying medical condition, treatment of that condition may be necessary. That may involve medications or surgery, depending on the diagnosis.

It is important to note that acrocyanosis usually resolves itself without treatment within a few months. However, it is still important to speak with a doctor if parents are concerned about their child’s symptoms. The doctor will be able to evaluate the situation and provide appropriate advice.

What Is the Prognosis of Infantile Acrocyanosis?

Infantile acrocyanosis is generally a benign condition with no long-term implications and resolves spontaneously within a few months. It is not associated with any underlying medical condition or physical disability. The prognosis for infantile acrocyanosis is excellent, and most babies will outgrow it without any long-term issues. However, if the symptoms persist for over three months, the doctor may recommend further testing to rule out other underlying medical conditions.

Conclusion

Infantile acrocyanosis is a condition that usually resolves itself within a few weeks or months. Therefore, it is not harmful and does not require any medical intervention. However, the symptoms persist over a few weeks or are severe. In that case, seeking medical attention is important to rule out any underlying medical conditions. Infantile acrocyanosis can be easily managed and treated with prompt diagnosis and proper treatment.

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Dr. Veerabhadrudu Kuncham
Dr. Veerabhadrudu Kuncham

Pediatrics

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