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Radionuclides: What Is It, Types, and Uses

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A radionuclide is a chemical element in an unstable state that emits radiation as it breaks and becomes more stable.

Written by

Dr. Kinjal Shah

Medically reviewed by

Dr. Rajesh Deshwal

Published At October 25, 2023
Reviewed AtOctober 25, 2023

What Are Radionuclides?

Radionuclides are the name for radioactive elements. A radionuclide is an atom with an unstable nucleus, which is a nucleus with the extra energy that may be transferred to an atomic electron or a newly formed radiation particle inside the nucleus. Some are produced artificially, either on purpose or as a consequence of nuclear processes, while others are produced naturally in the environment.

Half-lives are used to estimate the rate at which each radionuclide emits radiation. The amount of time it takes for half of the radioactive atoms present to decay is known as the radioactive half-life. As a radioisotope changes into another radioisotope, the process is known as radioactive decay, and radiation of some kind is released. The half-lives of certain radionuclides range from a few seconds to millions of years.

What Are the Types of Radionuclides?

While radionuclides come in various forms, they may be generally divided into two groups: natural and manmade.

  • Natural Radionuclides: Natural radionuclides are radioactive isotopes created by the radioactive decay of primordial isotopes that existed when the Earth formed and are found in the environment. These radionuclides can be found in the water, food, and air. Natural radionuclides include, for instance:

  1. Uranium-238 (U-238): Radium-226 and radon-222 are two daughter products of the naturally occurring radioactive element uranium-238 (U-238 disintegration). It is a substantial source of background radiation and may be found in water, rocks, and soil.

  2. Thorium-232 (Th-232):Radium-228 and radon-220 are two daughter products produced during the radioactive decay of thorium-232 (Th-232). It is a substantial source of background radiation and may be found in soil and rocks.

  3. Potassium-40 (K-40): All living things, including humans, contain potassium-40 (K-40), a radioactive isotope of the element. It contributes significantly to background radiation from natural sources and emits beta and gamma rays.

  4. Carbon-14 (C-14): C-14 is a naturally occurring radioactive carbon isotope produced in the high atmosphere by cosmic rays. To ascertain the age of old things, carbon dating is utilized.

  5. Radon-222 (Rn-222):Radium-226 decay produces the radioactive gas known as radon-222 (Rn-222). It may build up in poorly ventilated buildings and is the second greatest cause of lung cancer after smoking.

  • Man-Made Radionuclides: Artificial radionuclides usually referred to as man-made radionuclides, are radioactive isotopes that are produced by nuclear processes in reactors or particle accelerators but do not exist naturally. However, they are frequently developed for usage in industrial, scientific, and medical settings. Man-made radionuclides include, for instance:

  1. Technetium-99m (Tc-99m):The most widely used radionuclide in medical imaging is technetium-99m (Tc-99m), which is created in a nuclear reactor by hitting molybdenum-98 with neutrons.

  2. Iodine-131 (I-131): It is created in a nuclear reactor by hitting tellurium-130 with neutrons, and it is used to treat thyroid cancer and hyperthyroidism.

  3. Cobalt-60 (Co-60): Co-60 is made by hitting cobalt-59 with neutrons in a nuclear reactor and is utilized in industrial applications and cancer treatment.

  4. Fluorine-18 (F-18):It is created by blasting oxygen-18 with protons in a particle accelerator. F-18 is utilized in PET imaging to assess metabolic activities in the body.

  5. Strontium-89 (Sr-89): It is created in a nuclear reactor by hitting yttrium-89 with neutrons. It is used to treat bone pain in patients with bone metastases.

  6. Carbon-11 (C-11): It is created by blasting nitrogen-14 with protons in a particle accelerator. It is utilized in PET imaging to analyze biological processes.

What Are the Uses of Radionuclides?

Radioactive isotopes, referred to as radionuclides, have a wide range of applications in several industries. Among the widespread applications for radionuclides are:

  1. Medical Imaging: Radionuclides are often employed in medical imaging to detect and track disorders. To learn more about the composition and operation of the body, radiopharmaceuticals, or substances marked with a radionuclide, are given to patients and then detected by imaging technology. For instance, Technetium-99m is employed in several imaging procedures, including lung, heart, and bone examinations.

  2. Cancer Treatment: Certain radionuclides target cancer cells with radiation during cancer treatment. For instance, Yttrium-90 and Lutetium-177 are used to treat neuroendocrine tumors, whereas Iodine-131 is used to treat thyroid cancer.

  3. Uses in Industry: Radionuclides are used in industry for various purposes, including monitoring fluid flow, gauging the thickness of materials, and finding leaks in pipelines. For instance, Americium-241 is used in smoke detectors to ionize air particles when smoke is present.

  4. Food Irradiation: Radionuclides can be used to disinfect food and lengthen its shelf life through food irradiation. Irradiation eliminates bacteria, viruses, and other dangerous microbes without significantly altering the food's flavor or nutritional value.

  5. Research: Radionuclides are frequently used to understand biological processes better and create novel medications for disorders. For instance, Fluorine-18 is used in positron emission tomography (PET) imaging to examine glucose metabolism in the brain. Likewise, carbon-14 is used to research carbon fixation in plants.

  6. Biochemistry and Genetics: Radionuclides identify molecules and make it possible to trace chemical and physiological processes occurring in live organisms, such as DNA replication or amino acid transport in biochemistry and genetics.

In conclusion, radionuclides continue to play a crucial part in advancing science and technology. They have a variety of purposes in medicine, business, and research. But, to ensure the advantages outweigh the hazards, their usage must be carefully controlled.

What Are the Risks of Radionuclides?

Radioactively unstable atoms produce ionizing radiation as a kind of energy. If these are discharged or distributed in an unregulated way, there may be concerns for both human health and the environment. Radionuclide dangers include, among others:

  1. Radiation Exposure: Ionizing radiation is emitted by radionuclides, which can harm DNA, cells, and tissues. Excessive exposure levels can cause cancer, radiation illness, and even death.

  2. Contamination: Radionuclides can contaminate several elements of the environment, including the air, water, soil, and food. Once released, they have the potential to travel great distances on the wind and water, enter the food chain, and then build up in both animals and people.

  3. Long-Lasting Effects: Some radionuclides have lengthy half-lives, so they can continue to be radioactive for hundreds or even thousands of years. This increases the danger of long-term exposure since whatever pollution they may have created can last very long.

  4. Accidents: Radionuclide-related mishaps, including nuclear reactor meltdowns or radioactive material leaks, may harm human health and the environment. These occurrences can potentially discharge significant radiation levels, harming the ecosystem long term and having immediate negative health impacts.

  5. Nuclear Weapons: Nuclear weapons utilize radionuclides and provide a danger to international security. Nuclear weapons usage has the potential to result in extensive damage and long-term health consequences.

Conclusion

Radionuclides provide substantial benefits in areas like medicine, energy generation, and scientific study, despite the fact that they pose serious threats to human health and the environment. For instance, radionuclides are employed in cancer therapy and diagnostic imaging, enabling clinicians to diagnose and treat diseases more accurately. Moreover, they are utilized in nuclear power plants, which offer a dependable energy source that emits fewer greenhouse gasses than fossil fuels. Moreover, radionuclides are essential for scientific inquiry since they enable us to comprehend the basic characteristics of matter and the universe's beginnings. One can keep utilizing radionuclides for numerous beneficial purposes by further studying and developing new uses.

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Dr. Rajesh Deshwal
Dr. Rajesh Deshwal

HIV/AIDS specialist

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